Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Narsa Machireddy"'
Autor:
Chandra Mohan Tamatam, Lalith Kumar Venkareddy, Aparna Ankireddy, Narsa Machireddy, Sekhart P. Reddy
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 698 (2024)
Bronchopulmonary dysplasia (BPD) is a chronic condition affecting preterm infants, characterized by lung alveolar simplification/hypoalveolarization and vascular remodeling. The nuclear factor erythroid 2 like 2 (Nfe2l2, or Nrf2) plays a critical rol
Externí odkaz:
https://doaj.org/article/726ccc2d7823414b83a81e6e95ff8608
Publikováno v:
medRxiv
BackgroundPatients with sepsis-induced acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) commonly suffer from severe pulmonary thrombosis, but clinical trials of anti-coagulant therapies in sepsis and ARDS patients have failed. ARDS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61eebdad95a0ab394d9b97f349cfefff
https://europepmc.org/articles/PMC10081399/
https://europepmc.org/articles/PMC10081399/
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48792cd5370349a63a70074b7cef3927
https://doi.org/10.1096/fasebj.2022.36.s1.r2448
https://doi.org/10.1096/fasebj.2022.36.s1.r2448
Autor:
Bin Liu, Yi Peng, Dan Yi, Narsa Machireddy, Daoyin Dong, Karina Ramirez, Jingbo Dai, Rebecca Vanderpool, Maggie M. Zhu, Zhiyu Dai, You-Yang Zhao
Publikováno v:
European Respiratory Journal. 60:2102643
BackgroundNitrative stress is a characteristic feature of the pathology of human pulmonary arterial hypertension. However, the role of nitrative stress in the pathogenesis of obliterative vascular remodelling and severe pulmonary arterial hypertensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80bd68b23949e057120dafb28f6fc2a9
https://doi.org/10.1183/13993003.02643-2021
https://doi.org/10.1183/13993003.02643-2021
Autor:
Xiaojia Huang, Xianming Zhang, Narsa Machireddy, Gökhan M. Mutlu, Yun Fang, David Wu, You-Yang Zhao
Aging is a major risk factor of high incidence and increased mortality of acute respiratory distress syndrome (ARDS) and COVID-19. We repot that aging impairs the intrinsic FoxM1-dependent endothelial regeneration and vascular repair program and caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d3d7d67911de872ed252ae75f6523b
https://doi.org/10.1101/2021.04.29.442061
https://doi.org/10.1101/2021.04.29.442061
Publikováno v:
Circulation. 142
Introduction: Lung thrombosis (LT) and endothelial cell (EC) death are positively associated with mortality in sepsis-induced acute lung injury (ALI) patients, but anti-coagulants have failed in clinical trials of sepsis. Hypothesis: We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::936f238639ce2d334ebca68118b21b27
https://doi.org/10.1161/circ.142.suppl_3.12651
https://doi.org/10.1161/circ.142.suppl_3.12651
Autor:
Bin, Liu, Yi, Peng, Dan, Yi, Narsa, Machireddy, Daoyin, Dong, Karina, Ramirez, Jingbo, Dai, Rebecca, Vanderpool, Maggie M, Zhu, Zhiyu, Dai, You-Yang, Zhao
Publikováno v:
The European respiratory journal. 60(6)
Nitrative stress is a characteristic feature of the pathology of human pulmonary arterial hypertension. However, the role of nitrative stress in the pathogenesis of obliterative vascular remodelling and severe pulmonary arterial hypertension remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::009f1b5afb099d79499a306beeca755d
https://pubmed.ncbi.nlm.nih.gov/36549689
https://pubmed.ncbi.nlm.nih.gov/36549689
Autor:
Colin E. Evans, Roberto Machado, Xianming Zhang, Maggie M. Zhu, Narsa Machireddy, You Yang Zhao, Zhiyu Dai, Yi Peng
Publikováno v:
American journal of respiratory and critical care medicine. 198(11)
Rationale: Pulmonary arterial hypertension (PAH) is a devastating disease characterized by progressive vasoconstriction and obliterative vascular remodeling that leads to right heart failure (RHF) and death. Current therapies do not target vascular r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc6e9dbb2ed0a1cce37d1c63c92cb17
https://pubmed.ncbi.nlm.nih.gov/30001500
https://pubmed.ncbi.nlm.nih.gov/30001500
Autor:
Maggie M. Zhu, Yi Peng, Hua Jin, Narsa Machireddy, You Yang Zhao, Xianming Zhang, Zhijian Qian, Zhiyu Dai
Publikováno v:
American journal of respiratory and critical care medicine. 198(6)
Angioproliferative vasculopathy is a hallmark of pulmonary arterial hypertension (PAH). However, little is known about how endothelial cell (EC) and smooth muscle cell (SMC) crosstalk regulates the angioproliferative vascular remodeling.To investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4986e4a0df4b7e266a2621e72be6ed4e
https://pubmed.ncbi.nlm.nih.gov/29694238
https://pubmed.ncbi.nlm.nih.gov/29694238
Autor:
Dhananjaya V. Kalvakolanu, Michelle Vaz, Sekhar P. Reddy, Pavan Adiseshaiah, Narsa Machireddy
Publikováno v:
Journal of Cellular Physiology. 216:405-412
We and others have shown a persistently high induction of Fra-1 transcription factor (a dimeric partner of AP-1) levels by respiratory carcinogens in pulmonary epithelial cells. Fra-1 is frequently overexpressed in various human tumors and cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a73c44ed7da6c7c2296ae8867c6b28
https://doi.org/10.1002/jcp.21410
https://doi.org/10.1002/jcp.21410