Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice

Autor: Vasou, Andri, Paulus, Christina, Narloch, Janina, Gage, Zoe O., Rameix-Welti, Marie-Anne, Eleouet, Jean-François, Nevels, Michael, Randall, Richard E., Adamson, Catherine S.

Publikováno v: Antiviral Research
Antiviral Research, Elsevier Masson, 2018, 150, pp.79-92. ⟨10.1016/j.antiviral.2017.10.012⟩

Viral interferon (IFN) antagonists are a diverse class of viral proteins that counteract the host IFN response, which is important for controlling viral infections. Viral IFN antagonists are often multifunctional proteins that perform vital roles in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e77249d9ee2c4236debf368b32bdc604
https://hal.inrae.fr/hal-02627518/document

Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice.

Autor: Vasou A; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom., Paulus C; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom., Narloch J; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom., Gage ZO; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom., Rameix-Welti MA; UMR INSERM U1173 2I, UFR des Sciences de la Santé Simone Veil-UVSQ, 78180, Montigny-Le-Bretonneux, France; AP-HP, Laboratoire de Microbiologie, Hôpital Ambroise Paré, 92104, Boulogne-Billancourt, France., Eléouët JF; Unité de Virologie et Immunologie Moléculaires (UR892), INRA, Université Paris-Saclay, 78352, Jouy-en-Josas, France., Nevels M; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom., Randall RE; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom., Adamson CS; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, United Kingdom. Electronic address: csa21@st-andrews.ac.uk.

Publikováno v: Antiviral research [Antiviral Res] 2018 Feb; Vol. 150, pp. 79-92. Date of Electronic Publication: 2017 Oct 14.