Zobrazeno 1 - 10
of 713
pro vyhledávání: '"Narla, Mohandas"'
Autor:
Bin Hu, Han Gong, Ling Nie, Ji Zhang, Yanan Li, Dandan Liu, Huifang Zhang, Haihang Zhang, Lu Han, Chaoying Yang, Maohua Li, Wenwen Xu, Yukio Nakamura, Lihong Shi, Mao Ye, Christopher D. Hillyer, Narla Mohandas, Long Liang, Yue Sheng, Jing Liu
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Lysine succinylation (Ksu) has recently emerged as a protein modification that regulates diverse functions in various biological processes. However, the systemically and precise role of lysine succinylation in erythropoiesis remains to be fully eluci
Externí odkaz:
https://doaj.org/article/f81da794426a468c8181758571cf6adc
Autor:
Serge Cedrick Toya Mbiandjeu, Angela Siciliano, Alessandro Mattè, Enrica Federti, Massimiliano Perduca, Davide Melisi, Immacolata Andolfo, Angela Amoresano, Achille Iolascon, Maria Teresa Valenti, Francesco Turrini, Michele Bovi, Arianna Pisani, Antonio Recchiuti, Domenico Mattoscio, Veronica Riccardi, Luca Dalle Carbonare, Carlo Brugnara, Narla Mohandas, Lucia De Franceschi
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 454 (2024)
Aging is characterized by increased oxidation and reduced efficiency of cytoprotective mechanisms. Nuclear factor erythroid-2-related factor (Nrf2) is a key transcription factor, controlling the expression of multiple antioxidant proteins. Here, we s
Externí odkaz:
https://doaj.org/article/6113bcf2028948f886726cd52fe80fab
Autor:
Alessandro Matte, Anand B. Wilson, Federica Gevi, Enrica Federti, Antonio Recchiuti, Giulia Ferri, Anna Maria Brunati, Mario Angelo Pagano, Roberta Russo, Christophe Leboeuf, Anne Janin, Anna Maria Timperio, Achille Iolascon, Elisa Gremese, Lenny Dang, Narla Mohandas, Carlo Brugnara, Lucia De Franceschi
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Hereditary spherocytosis (HS) is the most common, nonimmune, hereditary, chronic hemolytic anemia after hemoglobinopathies. The genetic defects in membrane function causing HS lead to perturbation of the RBC metabolome, with altered glycolysis. In mi
Externí odkaz:
https://doaj.org/article/dca369d1197d4e2db25239462d156007
Autor:
Bérengère Koehl, Cédric Vrignaud, Mahmoud Mikdar, Thankam S Nair, Lucy Yang, Seyve Landry, Guy Laiguillon, Claudine Giroux‐Lathuile, Sophie Anselme‐Martin, Hanane El Kenz, Olivier Hermine, Narla Mohandas, Jean Pierre Cartron, Yves Colin, Olivier Detante, Raphaël Marlu, Caroline Le Van Kim, Thomas E Carey, Slim Azouzi, Thierry Peyrard
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp 1-14 (2023)
Abstract Blood phenotypes are defined by the presence or absence of specific blood group antigens at the red blood cell (RBC) surface, due to genetic polymorphisms among individuals. The recent development of genomic and proteomic approaches enabled
Externí odkaz:
https://doaj.org/article/f2d7a59490f64da5ad7587622cbb7e66
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Hematopoiesis requires finely tuned regulation of gene expression at each stage of development. The regulation of gene transcription involves not only individual transcription factors (TFs) but also transcription complexes (TCs) composed of
Externí odkaz:
https://doaj.org/article/ea65abb666e34417b71d6f2b495b0d9c
Autor:
Maisha Khair Nima, Angana Mukherjee, Saiful Arefeen Sazed, Muhammad Riadul Haque Hossainey, Ching Swe Phru, Fatema Tuj Johora, Innocent Safeukui, Anjan Saha, Afsana Alamgir Khan, Aung Swi Prue Marma, Russell E. Ware, Narla Mohandas, Barbara Calhoun, Rashidul Haque, Wasif Ali Khan, Mohammad Shafiul Alam, Kasturi Haldar
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Emerging resistance to artemisinin drugs threatens the elimination of malaria. Resistance is widespread in South East Asia (SEA) and Myanmar. Neighboring Bangladesh, where 90% of infections occur in the Chittagong Hill Tracts (CHTs), lacks r
Externí odkaz:
https://doaj.org/article/793f8d0f3d01417f81e2313a98837877
Autor:
Dorota Szpak, Chloe Turpin, Utku Goreke, Katarzyna Bialkowska, Kamila M. Bledzka, Dmitriy Verbovetskiy, Narla Mohandas, Umut A. Gurkan, Jun Qin, Edward F. Plow, Elzbieta Pluskota
Publikováno v:
Blood Advances. 7:1739-1753
Kindlin-3 (K3) is critical for the activation of integrin adhesion receptors in hematopoietic cells. In humans and mice, K3 deficiency is associated with impaired immunity and bone development, bleeding, and aberrant erythrocyte shape. To delineate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9044a4660faf3cf35f8417e551bdcd
https://doi.org/10.1182/bloodadvances.2022008498
https://doi.org/10.1182/bloodadvances.2022008498
Autor:
Anupama Narla, Narla Mohandas
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/39774952f5f7477c854b87bf613f4bc3
Autor:
Lubica Draberova, Helena Draberova, Lucie Potuckova, Ivana Halova, Monika Bambouskova, Narla Mohandas, Petr Draber
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Protein 4.1R, a member of the 4.1 family, functions as a bridge between cytoskeletal and plasma membrane proteins. It is expressed in T cells, where it binds to a linker for activation of T cell (LAT) family member 1 and inhibits its phosphorylation
Externí odkaz:
https://doaj.org/article/dc4978373d5f4c5f85f88b83a51492d6
Autor:
Abdullah Mahmood Ali, Yumin Huang, Ronald Feitosa Pinheiro, Fumin Xue, Jingping Hu, Nicholas Iverson, Daniela Hoehn, Diego Coutinho, Jehanzeb Kayani, Brian Chernak, Joseph Lane, Christopher Hillyer, Naomi Galili, Joseph Jurcic, Narla Mohandas, Xiuli An, Azra Raza
Publikováno v:
Blood Advances, Vol 2, Iss 12, Pp 1393-1402 (2018)
Abstract: Anemia is the defining feature in most patients with myelodysplastic syndromes (MDS), yet defects in erythropoiesis have not been well characterized. We examined freshly obtained bone marrow (BM) samples for stage-specific abnormalities dur
Externí odkaz:
https://doaj.org/article/53545c28418145669201fd7942148022