Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Narkunaraja Shanmugam"'
Publikováno v:
ACS Applied Bio Materials. 4:8433-8442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0464b7f2e00952dfbd62c772b9d6c2cd
https://doi.org/10.1021/acsabm.1c00963
https://doi.org/10.1021/acsabm.1c00963
Publikováno v:
ACS applied bio materials. 4(12)
Inflammation is one of the basic pathophysiologically important components in many life-threatening diseases. Metallic nanoparticles play a crucial role in biomedical applications. The present study was aimed at investigating the ameliorative effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eaa73583f78247780a4c49ce27a99d2a
https://pubmed.ncbi.nlm.nih.gov/35005949
https://pubmed.ncbi.nlm.nih.gov/35005949
Publikováno v:
Cell and tissue research. 389(2)
There is a major unmet need for the development of effective therapies for diabetes induced inflammation. Increased adenosine-uridine rich elements (AREs) containing mRNAs of inflammatory molecules are reported in inflamed monocytes. Destabilizing th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8d1478d34524888a23e8b8e0dfc9c7
https://pubmed.ncbi.nlm.nih.gov/35604451
https://pubmed.ncbi.nlm.nih.gov/35604451
Publikováno v:
European journal of pharmacology. 920
Altered mRNA metabolism is a feature of many inflammatory diseases. Post transcriptional regulation of interferon-γ-inducible protein (IP)-10 has been uncharacterized in diabetes conditions. RNA-affinity capture method and RNA immuno-precipitation r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416684df9b82c17d58768f40183a4523
https://pubmed.ncbi.nlm.nih.gov/34914972
https://pubmed.ncbi.nlm.nih.gov/34914972
Publikováno v:
Journal of Nanoscience and Nanotechnology. 18:3077-3086
Diabetes, a chronic metabolic disorder associated with significantly accelerated rates of inflammation. Gold nanoparticle plays a crucial role in biomedical applications. We described the development of hetero-functionalized gold nanoparticles (hfAuN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::556b146ab0014969bf21f43f85884b0c
https://doi.org/10.1166/jnn.2018.14648
https://doi.org/10.1166/jnn.2018.14648
Publikováno v:
Journal of Leukocyte Biology. 92:1055-1067
MDA changed cytokine/chemokines mRNA profiles in lymphocytes; increased cytokines expression is via oxidative stress, p38MAPK, and PKC pathways. Diabetes is an inflammatory disease promoted by alterations in immune cell function. Animal study indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc95ed27788c179ed89c03c723f93bcd
https://doi.org/10.1189/jlb.1211617
https://doi.org/10.1189/jlb.1211617
Publikováno v:
Journal of Biological Chemistry. 283:36221-36233
Advanced glycation end products play major roles in diabetic complications. They act via their receptor RAGE to induce inflammatory genes such as cyclooxygenase-2 (COX-2). We examined the molecular mechanisms by which the RAGE ligand, S100b, induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8afe6cb4632ca664e9a08cc368b0ce
https://doi.org/10.1074/jbc.m806322200
https://doi.org/10.1074/jbc.m806322200
Autor:
Jiing Kuan Yee, Narkunaraja Shanmugam, Rama Natarajan, David Hawkins, Feng Miao, Marpadga A. Reddy, Bing Ren, Yan Li
Publikováno v:
Journal of Biological Chemistry. 283:26771-26781
Nuclear factor κ-B (NF-κB)-regulated inflammatory genes, such as TNF-α (tumor necrosis factor-α), play key roles in the pathogenesis of inflammatory diseases, including diabetes and the metabolic syndrome. However, the nuclear chromatin mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9975854c5b99b941cce7cd45f4a9eb0
https://doi.org/10.1074/jbc.m802800200
https://doi.org/10.1074/jbc.m802800200
Publikováno v:
Cellularmolecular biology letters. 20(4)
Malondialdehyde (MDA) is a highly reactive endogenous product of thromboxane synthesis in the prostagland and lipid peroxidation by reactive oxygen species. Elevated MDA levels occur in diabetes and atherosclerotic plaques. The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b33871af12bdff34db1efdb0243297
https://pubmed.ncbi.nlm.nih.gov/26305464
https://pubmed.ncbi.nlm.nih.gov/26305464
Publikováno v:
Diabetes. 52:1256-1264
Monocyte activation and adhesion to the endothelium play important roles in inflammatory and cardiovascular diseases. These processes are further aggravated by hyperglycemia, leading to cardiovascular complications in diabetes. We have previously sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3780274444dc28e8038b90eff5bf655d
https://doi.org/10.2337/diabetes.52.5.1256
https://doi.org/10.2337/diabetes.52.5.1256