Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Narjis Fatima"'
Publikováno v:
FACETS, Vol 7, Iss , Pp 792-808 (2022)
The CLOCK gene is a core component of the circadian clock and regulates various aspects of metabolism. Therefore, any variation that affects the function/expression of the CLOCK gene may contribute to the manifestation of metabolic disorders such as
Externí odkaz:
https://doaj.org/article/4d3a6cb97f5442948bb43d06edd38311
Autor:
Narjis Fatima, Yandong Shen, Kyle Crassini, Edwin J. Iwanowicz, Henk Lang, Donald S. Karanewsky, Richard I. Christopherson, Stephen P. Mulligan, Oliver G. Best
Publikováno v:
eJHaem, Vol 2, Iss 1, Pp 81-93 (2021)
Abstract Despite advances in therapy, a significant proportion of patients with chronic lymphocytic leukemia (CLL) relapse with drug resistant disease. Novel treatment approaches are required, particularly for high risk disease. The imipridones repre
Externí odkaz:
https://doaj.org/article/0664da1a27014eaf8dc8331aa7119ac2
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225056 (2019)
Natural flora is the richest source of novel therapeutic agents due to their immense chemical diversity and novel biological properties. In this regard, eighteen natural products belonging to different chemical classes were evaluated for their thymid
Externí odkaz:
https://doaj.org/article/617e92d9a07b4f01a09245991783e8ac
Autor:
M. Iqbal Choudhary, Mahwish Siddiqui, Atia-tul-Wahab, Sammer Yousuf, Narjis Fatima, Malik S. Ahmad, Hani Choudhry
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
In search of selective and effective anti-cancer agents, eight metabolites of anti-cancer steroid, drostanolone enanthate (1), were synthesized via microbial biotransformation. Enzymes such as reductase, oxidase, dehydrogenase, and hydrolase from Cep
Externí odkaz:
https://doaj.org/article/22a10d63726446e0bd0c093c4e0be91d
Autor:
Mahwish Siddiqui, Malik Shoaib Ahmad, Atia-Tul- Wahab, Sammer Yousuf, Narjis Fatima, Nimra Naveed Shaikh, Atta-Ur- Rahman, M Iqbal Choudhary
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171476 (2017)
Seven metabolites were obtained from the microbial transformation of anabolic-androgenic steroid mibolerone (1) with Cunninghamella blakesleeana, C. echinulata, and Macrophomina phaseolina. Their structures were determined as 10β,17β-dihydroxy-7α,
Externí odkaz:
https://doaj.org/article/e53385c960924071ac155295f0bf3bfe
Autor:
Engin Erzin, Syeda Narjis Fatima
Publikováno v:
Speech Communication. 132:70-82
Emotional dependencies play a crucial role in understanding complexities of dyadic interactions. Recent studies have shown that affect recognition tasks can benefit by the incorporation of a particular interaction’s context, however, the investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20120af7b2de4da912b0622b1a3e7bf
https://doi.org/10.1016/j.specom.2021.05.010
https://doi.org/10.1016/j.specom.2021.05.010
Autor:
Kyle Crassini, Narjis Fatima, Edwin Iwanowicz, Oliver Giles Best, Yandong Shen, Richard I. Christopherson, Donald S. Karanewsky, Henk Lang, Stephen P. Mulligan
Publikováno v:
eJHaem. 2:81-93
Despite advances in therapy, a significant proportion of patients with chronic lymphocytic leukemia (CLL) relapse with drug resistant disease. Novel treatment approaches are required, particularly for high risk disease. The imipridones represent a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2809a1c9e92e16c99a61092bd0059409
https://doi.org/10.1002/jha2.160
https://doi.org/10.1002/jha2.160
Autor:
Narjis Fatima, Yandong Shen, Kyle Crassini, Edwin J. Iwanowicz, Henk Lang, Donald S. Karanewsky, Richard I Christopherson, Stephen P Mulligan, O. Giles Best
Despite advances in treatment, a significant proportion of patients with chronic lymphocytic leukaemia (CLL) will relapse with drug-resistant disease.Recent studies demonstrate that the imipridones ONC-201 and ONC-212 and the more potent TR-compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f13f551dcc5277809bd4feabf23a7cca
https://doi.org/10.1101/2022.03.07.483345
https://doi.org/10.1101/2022.03.07.483345
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 41(3)
In mammals, AMPylation of cellular proteins is carried out by Huntingtin yeast-interacting protein E, and pseudokinase SelO. Lysates from mouse B16-F10 melanoma cells have been fractionated by immuno-precipitation using magnetic Dynabeads coated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe3aea9c2efed20da195a8a5c08432e
https://pubmed.ncbi.nlm.nih.gov/34738868
https://pubmed.ncbi.nlm.nih.gov/34738868
Autor:
Suneet Sandhu, O. Giles Best, Stephen P. Mulligan, Narjis Fatima, Richard I. Christopherson, Kyle Crassini, Yandong Shen
Publikováno v:
Leukemia & Lymphoma. 60:1632-1643
Several key pathways mediate signaling via the B-cell receptor, including the mitogen-activated protein kinase-ERK1/2 pathway. However, inhibition of MEK1/2, a key component of the MAPK-ERK1/2 signaling cascade, results in paradoxical activation of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ace7fbefaf9b177fc9c914a1d28bf9
https://doi.org/10.1080/10428194.2018.1542148
https://doi.org/10.1080/10428194.2018.1542148