Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Nariyoshi Shinomiya"'
Autor:
Yuya Shirai, Akiyoshi Nakayama, Yusuke Kawamura, Yu Toyoda, Masahiro Nakatochi, Seiko Shimizu, Nariyoshi Shinomiya, Yukinori Okada, Hirotaka Matsuo, Japan Gout Genomics Consortium (Japan Gout)
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 6, Pp 534-539 (2022)
Objective The effects of coffee consumption on serum uric acid (SUA) levels and gout risk are controversial. There have hitherto been no reports based on Mendelian randomization (MR) analysis of its effects that consider pleiotropy. Here, we evaluate
Externí odkaz:
https://doaj.org/article/cea811b638814fe29f677f03354ce3e4
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The dual-use risk of infectious disease research using enhanced potential pandemic pathogens (ePPP), particularly gain-of-function (GOF) research, has been debated since 2011. As of now, research is supported on the condition that the research plan i
Externí odkaz:
https://doaj.org/article/4729599452474de09a08ea47c1ed9025
Autor:
Yu Toyoda, Yusuke Kawamura, Akiyoshi Nakayama, Keito Morimoto, Seiko Shimizu, Yuki Tanahashi, Takashi Tamura, Takaaki Kondo, Yasufumi Kato, Kimiyoshi Ichida, Hiroshi Suzuki, Nariyoshi Shinomiya, Yasushi Kobayashi, Tappei Takada, Hirotaka Matsuo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Dysfunctional missense variant of organic anion transporter 10 (OAT10/SLC22A13), rs117371763 (c.1129C>T; p.R377C), is associated with a lower susceptibility to gout. OAT10 is a urate transporter; however, its physiological role in urate handling rema
Externí odkaz:
https://doaj.org/article/ea97d17ed7d34b7ca38d72bf4f4c0f3e
Autor:
Masashi Arake, Hiroyuki Ohta, Aki Tsuruhara, Yasushi Kobayashi, Nariyoshi Shinomiya, Hiroaki Masaki, Yuji Morimoto
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Measurement of event-related potentials (ERPs) in simulated and real environments is advantageous for understanding cognition and behavior during practice of goal-directed activities. Recently, instead of using task-irrelevant “probe stimuli” to
Externí odkaz:
https://doaj.org/article/9336a26daed84084a6797e5d50e764bf
Publikováno v:
Frontiers in Political Science, Vol 4 (2022)
Genome editing technologies are increasingly coming under scrutiny, based on various social value judgments in biomedical research, clinical care, and public health. A central cause of this sociotechnical tension is that these technologies are capabl
Externí odkaz:
https://doaj.org/article/a2f53b7d6d6544889ed4f797b7340274
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 380 (2022)
In recent years, there has been increasing evidence that gut microbiota is associated with the onset and exacerbation of various diseases, such as gastrointestinal cancer. For instance, it is well known that local inflammation of the intestinal tract
Externí odkaz:
https://doaj.org/article/722f418ce1304a0d84754b4ff9c58cec
Autor:
Masayuki Sakiyama, Hirotaka Matsuo, Hirofumi Nakaoka, Yusuke Kawamura, Makoto Kawaguchi, Toshihide Higashino, Akiyoshi Nakayama, Airi Akashi, Jun Ueyama, Takaaki Kondo, Kenji Wakai, Yutaka Sakurai, Ken Yamamoto, Hiroshi Ooyama, Nariyoshi Shinomiya
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Background Gout is a common disease resulting from hyperuricemia which causes acute arthritis. A recent genome-wide association study (GWAS) of gout identified three new loci for gout in Han Chinese: regulatory factor X3 (RFX3), potassium vo
Externí odkaz:
https://doaj.org/article/3fdd0a2def0c4ba9a6ed1afd843b8632
Autor:
Keita Kouzu, Hironori Tsujimoto, Yusuke Ishibashi, Hanae Shinada, Isawo Oikawa, Yoji Kishi, Nariyoshi Shinomiya, Hideki Ueno
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 24, p 5966 (2021)
The current study investigated the impact of preoperative fall risk assessment score (FRAS) on long-term prognoses in patients with esophageal cancer (EC). A total of 161 patients with EC who underwent curative surgery were classified into a high-ris
Externí odkaz:
https://doaj.org/article/780cdb7c535747df8126c8a5fa736e4c
Autor:
Yusuke Kawamura, Akiyoshi Nakayama, Seiko Shimizu, Yu Toyoda, Yuichiro Nishida, Asahi Hishida, Sakurako Katsuura-Kamano, Kenichi Shibuya, Takashi Tamura, Makoto Kawaguchi, Satoko Suzuki, Satoko Iwasawa, Hiroshi Nakashima, Rie Ibusuki, Hirokazu Uemura, Megumi Hara, Kenji Takeuchi, Tappei Takada, Masashi Tsunoda, Kokichi Arisawa, Toshiro Takezaki, Keitaro Tanaka, Kimiyoshi Ichida, Kenji Wakai, Nariyoshi Shinomiya, Hirotaka Matsuo
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 1012 (2021)
Background: Renal hypouricemia (RHUC) is characterized by a low serum uric acid (SUA) level and high fractional excretion of uric acid (FEUA). Further studies on FEUA in hypouricemic individuals are needed for a more accurate diagnosis of RHUC. Metho
Externí odkaz:
https://doaj.org/article/374df1a21f18430bb1805654d36a9794
Publikováno v:
Medicines, Vol 8, Iss 8, p 45 (2021)
There has been increasing evidence that a local inflammatory response stimulates tumor cells to acquire metastatic potential, and the concept of inflammatory oncotaxis has been spreading in recent years. However, the interaction between microbial inf
Externí odkaz:
https://doaj.org/article/3e1f502928bc49a79e166cecac96b31c