Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Narin Osman"'
Autor:
Danielle Kamato, Mai Gabr, Hirushi Kumarapperuma, Zheng J. Chia, Wenhua Zheng, Suowen Xu, Narin Osman, Peter J. Little
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14425 (2022)
Aims: G protein-coupled receptor (GPCR) transactivation of kinase receptors greatly expands the actions attributable to GPCRs. Thrombin, via its cognate GPCR, protease-activated receptor (PAR)-1, transactivates tyrosine and serine/threonine kinase re
Externí odkaz:
https://doaj.org/article/74d33d8769ce4905af5a3d3926bfa928
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Thyroid hormones (THs) are ancient hormones that not only influence the growth, development and metabolism of vertebrates but also affect the metabolism of (at least some) bacteria. Synthesized in the thyroid gland (or follicular cells in fish not ha
Externí odkaz:
https://doaj.org/article/939b8d2fcc774e9a93b6bfbeb1573d82
Autor:
Danielle Kamato, Venkata Vijayanand Bhaskarala, Nitin Mantri, Tae Gyu Oh, Dora Ling, Reearna Janke, Wenhua Zheng, Peter J Little, Narin Osman
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180842 (2017)
G protein coupled receptor (GPCR) signalling covers three major mechanisms. GPCR agonist engagement allows for the G proteins to bind to the receptor leading to a classical downstream signalling cascade. The second mechanism is via the utilization of
Externí odkaz:
https://doaj.org/article/2fa9de4c2e5542f6b4915ee6da16b059
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
Age-related macular degeneration (AMD) is a retinal disease evident after the age of 50 that damages the macula in the centre of retina. It leads to a loss of central vision with retained peripheral vision but eventual blindness occurs in many cases.
Externí odkaz:
https://doaj.org/article/b2b51303e35f4acc82941774d2d96b10
Vascular wall proteoglycan synthesis and structure as a target for the prevention of atherosclerosis
Publikováno v:
Vascular Health and Risk Management, Vol Volume 3, Pp 117-124 (2007)
Peter J Little1, 2, 3, Mandy L. Ballinger1, Narin Osman1,31Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, Australia; Monash University, Departments of 2Medicine and 3Immunology, Central and Eastern Clinical School, Al
Externí odkaz:
https://doaj.org/article/d23c360c50904f8fb99efe6f16379fa6
Publikováno v:
Vascular Health and Risk Management, Vol Volume 1, Pp 199-208 (2005)
Soniya Survase1,2, Melanie E Ivey1,2, Julie Nigro1,2, Narin Osman1, Peter J Little1,2,31Cell Biology of Diabetes Laboratory, Baker Heart Research Institute, Melbourne, VIC, Australia; 2Monash University, Department of Medicine (Alfred Hospital), Melb
Externí odkaz:
https://doaj.org/article/66973f4856a34be3b783209d91d9440a
Publikováno v:
The Scientific World Journal, Vol 5, Pp 515-520 (2005)
Externí odkaz:
https://doaj.org/article/7a63e3b4dc444937bcc3993a184a48db
Publikováno v:
The Scientific World Journal, Vol 5, Pp 521-526 (2005)
Externí odkaz:
https://doaj.org/article/ce0b39bad18e4710af4ce74d0e0e38ef
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1527 (2017)
The discovery of the BRAFV600E mutation led to the development of vemurafenib (PLX4032), a selective BRAF inhibitor specific to the kinase, for the treatment of metastatic melanomas. However, initial success of the drug was dampened by the developmen
Externí odkaz:
https://doaj.org/article/304544ceb4564cc19b0f2a1ec61f9c55
Publikováno v:
Journal of Cell Communication and Signaling. 13:539-548
Protease activated receptors (PARs) transactivate both epidermal growth factor receptors (EGFR) and transforming growth factor (TGF)-β receptors (TGFBR1) in vascular smooth muscle leading to the increased expression of genes (CHST11 and CHSY1) which