Zobrazeno 1 - 10
of 1 284
pro vyhledávání: '"Nariman F."'
Autor:
Kirill V. Odarenko, Aleksandra V. Sen’kova, Oksana V. Salomatina, Oleg V. Markov, Nariman F. Salakhutdinov, Marina A. Zenkova, Andrey V. Markov
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Soloxolone amides are semisynthetic triterpenoids that can cross the blood-brain barrier and inhibit glioblastoma growth both in vitro and in vivo. Here we investigate the impact of these compounds on processes associated with glioblastoma invasivene
Externí odkaz:
https://doaj.org/article/8bda56d571fa47af9a22c1eedf902d68
Autor:
Arseny D. Moralev, Oksana V. Salomatina, Ivan V. Chernikov, Nariman F. Salakhutdinov, Marina A. Zenkova, Andrey V. Markov
Publikováno v:
ACS Omega, Vol 8, Iss 51, Pp 48813-48824 (2023)
Externí odkaz:
https://doaj.org/article/97f53e210b5b4b3c8c867f70daf22953
Autor:
Arseny D. Moralev, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Andrey V. Markov
Publikováno v:
Molecules, Vol 29, Iss 20, p 4939 (2024)
Multidrug resistance (MDR) remains a significant challenge in cancer therapy, primarily due to the overexpression of transmembrane drug transporters, with P-glycoprotein (P-gp) being a central focus. Consequently, the development of P-gp inhibitors h
Externí odkaz:
https://doaj.org/article/99f440c0327c4dca97ff2cc2a61798c4
Autor:
Daria S. Gorina, Anastasiya V. Lastovka, Artem D. Rogachev, Alexandra V. Podturkina, Alla V. Pavlova, Oleg V. Ardashov, Nikolai S. Li-Zhulanov, Tatyana G. Tolstikova, Konstantin P. Volcho, Nariman F. Salakhutdinov
Publikováno v:
Molecules, Vol 29, Iss 18, p 4498 (2024)
The novel antiparkinsonian agent PA-96 is the focus of our research. PA-96 supported the survival of cultured naïve dopamine neurons, alleviated motor deficits in MPTP and haloperidol-based mice models of Parkinson’s disease, and increased the den
Externí odkaz:
https://doaj.org/article/cb86bc19e3b945f88ff2fa89d8714c39
Autor:
Nikolai S. Li-Zhulanov, Artem D. Rogachev, Yuri V. Gatilov, Konstantin P. Volcho, Nariman F. Salakhutdinov
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1780 (2024)
The reaction of (−)-nopol mesylate with piperazine in acetonitrile under reflux, afforded symmetric 1,4-bis(2-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl)piperazine in a good yield. The compound was fully characterized and its structure
Externí odkaz:
https://doaj.org/article/cf5e49e7de0341da9716ea28d2a53644
Autor:
Kseniya S. Kovaleva, Olga I. Yarovaya, Irina A. Chernyshova, Alexandra L. Zakharenko, Sergey V. Cheresiz, Amirhossein Azimirad, Andrey G. Pokrovsky, Olga I. Lavrik, Nariman F. Salakhutdinov
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1743 (2023)
New imidazolidine-2,4,5-triones with norabietic, nordehydroabietic, and adamantane substituents were synthesized by reacting oxalyl chloride and the corresponding ureas, providing good yields. Bioisosteric replacement of the ureide group with a parab
Externí odkaz:
https://doaj.org/article/762c351df9fd453b962ba98d14d82149
Autor:
Svetlana V. Belenkaya, Iuliia A. Merkuleva, Olga I. Yarovaya, Varvara Yu Chirkova, Elena A. Sharlaeva, Daniil V. Shanshin, Ekaterina A. Volosnikova, Sergey Z. Vatsadze, Mikhail V. Khvostov, Nariman F. Salakhutdinov, Dmitriy Shcherbakov
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/d70b4ae2479f41fb94be18a79decf063
Autor:
Mikhail E. Blokhin, Sergey O. Kuranov, Mikhail V. Khvostov, Vladislav V. Fomenko, Olga A. Luzina, Natalia A. Zhukova, Cham Elhajjar, Tatiana G. Tolstikova, Nariman F. Salakhutdinov
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 3, Pp 2230-2247 (2023)
Metabolic syndrome is a complex of abnormalities involving impaired glucose and lipid metabolism, which needs effective pharmacotherapy. One way to reduce lipid and glucose levels associated with this pathology is the simultaneous activation of nucle
Externí odkaz:
https://doaj.org/article/11da43e749494af6a90f1d0a03313e03
Autor:
Irina V. Ilyina, Nikolai S. Li-Zhulanov, Yuri V. Gatilov, Konstantin P. Volcho, Alexander Yu. Sidorenko, Vladimir E. Agabekov, Nariman F. Salakhutdinov
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1734 (2023)
The development of highly efficient methods for the synthesis of chemical products by using renewable raw materials is one of the topical areas of medicinal chemistry. The paper presents the synthesis of (2aR,2a1S,5aR,9bR)-4-isopropyl-7,8-dimethoxy-2
Externí odkaz:
https://doaj.org/article/b8bb8144a711483d9c48e071fe747f13
Autor:
Svetlana V. Belenkaya, Iuliia A. Merkuleva, Olga I. Yarovaya, Varvara Yu. Chirkova, Elena A. Sharlaeva, Daniil V. Shanshin, Ekaterina A. Volosnikova, Sergey Z. Vatsadze, Mikhail V. Khvostov, Nariman F. Salakhutdinov, Dmitriy N. Shcherbakov
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Despite the long history of use and the knowledge of the genetics and biochemistry of E. coli, problems are still possible in obtaining a soluble form of recombinant proteins in this system. Although, soluble protein can be obtained both in the cytop
Externí odkaz:
https://doaj.org/article/46c0a4c44b8147dfae40d0e507f092ef