Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nariman, Salakhutdinov"'
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1618 (2023)
Usnic acid is a well-known secondary lichen metabolite exhibiting a broad spectrum of biological activity. Previously it was shown that the reaction of usnic acid with various amines resulted in enamine-bond formation instead of the C(11)=O carbonyl
Externí odkaz:
https://doaj.org/article/b525048e92404e7da05a99e42a8e9064
Autor:
Stela Dragomanova, Velichka Andonova, Konstantin Volcho, Nariman Salakhutdinov, Reni Kalfin, Lyubka Tancheva
Publikováno v:
Life, Vol 13, Iss 10, p 2086 (2023)
The investigation of monoterpenes as natural products has gained significant attention in the search for new pharmacological agents due to their ability to exhibit a wide range in biological activities, including antifungal, antibacterial, antioxidan
Externí odkaz:
https://doaj.org/article/65354d348daf4d3aafa3c0f6d7ebe651
Autor:
Elmira Gibadullina, Margarita Neganova, Yulia Aleksandrova, Hoang Bao Tran Nguyen, Alexandra Voloshina, Mikhail Khrizanforov, Thi Thu Nguyen, Ekaterina Vinyukova, Konstantin Volcho, Dmitry Tsypyshev, Anna Lyubina, Syumbelya Amerhanova, Anna Strelnik, Julia Voronina, Daut Islamov, Rakhmetulla Zhapparbergenov, Nurbol Appazov, Beauty Chabuka, Kimberley Christopher, Alexander Burilov, Nariman Salakhutdinov, Oleg Sinyashin, Igor Alabugin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12637 (2023)
The utility of sterically hindered phenols (SHPs) in drug design is based on their chameleonic ability to switch from an antioxidant that can protect healthy tissues to highly cytotoxic species that can target tumor cells. This work explores the biol
Externí odkaz:
https://doaj.org/article/1071746952fa40ceb533c9ed9f0a574a
Autor:
Yulia Aleksandrova, Aldar Munkuev, Evgenii Mozhaitsev, Evgenii Suslov, Dmitry Tsypyshev, Kirill Chaprov, Roman Begunov, Konstantin Volcho, Nariman Salakhutdinov, Margarita Neganova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9743 (2023)
Novel monoterpene-based hydroxamic acids of two structural types were synthesized for the first time. The first type consisted of compounds with a hydroxamate group directly bound to acyclic, monocyclic and bicyclic monoterpene scaffolds. The second
Externí odkaz:
https://doaj.org/article/5a6ee81fa940424db659a0af1b6a9b93
Autor:
Yulia Aleksandrova, Kirill Chaprov, Alexandra Podturkina, Oleg Ardashov, Ekaterina Yandulova, Konstantin Volcho, Nariman Salakhutdinov, Margarita Neganova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5842 (2023)
Parkinson’s disease is the second most common neurodegenerative disease. Unfortunately, there is still no definitive disease-modifying therapy. In our work, the antiparkinsonian potential of trans-epoxide (1S,2S,3R,4S,6R)-1-methyl-4-(prop-1-en-2-yl
Externí odkaz:
https://doaj.org/article/88b7955197d2449ca9111be49f214f3c
Autor:
Darya Pon`kina, Sergey Kuranov, Mikhail Khvostov, Nataliya Zhukova, Yulia Meshkova, Mariya Marenina, Olga Luzina, Tatyana Tolstikova, Nariman Salakhutdinov
Publikováno v:
Molecules, Vol 28, Iss 1, p 396 (2023)
Free fatty acid receptor-1 (FFAR1) is one of the possible therapeutic targets in the search for new hepatoprotective drugs. FFAR1 agonists were found to have hypolipidemic, antifibrotic, anti-inflammatory, antiproliferative and antioxidant effects in
Externí odkaz:
https://doaj.org/article/67cb3c41eb75465ab1fb6d55ecc853e9
Autor:
Sergey Kuranov, Mariya Marenina, Dmitriy Ivankin, Mikhail Blokhin, Sergey Borisov, Tatyana Khomenko, Olga Luzina, Mikhail Khvostov, Konstantin Volcho, Tatyana Tolstikova, Nariman Salakhutdinov
Publikováno v:
Molecules, Vol 27, Iss 24, p 8663 (2022)
Natural and synthetic coumarins are often considered privileged scaffolds for obtaining pharmacological agents with hypoglycemic activity. Chemical modification of coumarins often leads to antidiabetic agents with greater efficacy. In the present wor
Externí odkaz:
https://doaj.org/article/90b30d32a34f48f0a43503a8e40e6201
Autor:
Darya Pon`kina, Sergey Kuranov, Nataliya Zhukova, Yulia Meshkova, Mikhail Khvostov, Olga Luzina, Tatyana Tolstikova, Nariman Salakhutdinov
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 1 (2022)
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease caused by impaired lipid and carbohydrate metabolism, and is characterized by fatty degeneration, necrosis, inflammation, and fibrosis of hepatocytes. There are currently no approved
Externí odkaz:
https://doaj.org/article/d1f8b7323d4d47139b0fc732a3100d35
Autor:
Stela Dragomanova, Maria Lazarova, Aldar Munkuev, Evgeniy Suslov, Konstantin Volcho, Nariman Salakhutdinov, Amina Bibi, Jóhannes Reynisson, Elina Tzvetanova, Albena Alexandrova, Almira Georgieva, Diamara Uzunova, Miroslava Stefanova, Reni Kalfin, Lyubka Tancheva
Publikováno v:
Molecules, Vol 27, Iss 17, p 5456 (2022)
Alzheimer’s disease (AD) is a neurodegenerative disease associated with memory impairment and other central nervous system (CNS) symptoms. Two myrtenal–adamantane conjugates (MACs) showed excellent CNS potential against Alzheimer’s models. Adam
Externí odkaz:
https://doaj.org/article/b8e868069d7749d88d7c9e5385a7429f
Autor:
Neganova, Yulia Aleksandrova, Aldar Munkuev, Evgenii Mozhaitsev, Evgenii Suslov, Dmitry Tsypyshev, Kirill Chaprov, Roman Begunov, Konstantin Volcho, Nariman Salakhutdinov, Margarita
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9743
Novel monoterpene-based hydroxamic acids of two structural types were synthesized for the first time. The first type consisted of compounds with a hydroxamate group directly bound to acyclic, monocyclic and bicyclic monoterpene scaffolds. The second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9adbd39822cf4dc4efd6f848fa07b49e