Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Narikazu, Uzawa"'
Autor:
Mitsunobu Otsuru, Nobuhiro Yamakawa, Tadaaki Kirita, Shin-ichi Yamada, Hiroshi Kurita, Takuma Kugimoto, Hiroyuki Harada, Takumi Hasegawa, Masaya Akashi, Akinori Takeshita, Narikazu Uzawa, Masahiro Umeda, Souichi Yanamoto, Tomohiro Yamada
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 3, Pp 1628-1637 (2024)
Background/purpose: For unresectable recurrent/metastatic head and neck cancer, pembrolizumab alone or pembrolizumab combined with cisplatin and 5-fluorouracil is the first-line therapy, depending on the PD-L1 combined positive score (CPS). However,
Externí odkaz:
https://doaj.org/article/d2f24cf1cb3f4a29b711a1dcdb09c99c
Clinical relationships between the intratumoral microbiome and risk factors for head and neck cancer
Autor:
Masakazu Hamada, Kyoko Nishiyama, Ryota Nomura, Tatsuya Akitomo, Chieko Mitsuhata, Yoshiaki Yura, Kazuhiko Nakano, Michiyo Matsumoto-Nakano, Narikazu Uzawa, Hiroaki Inaba
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39284- (2024)
A bioinformatic analysis is a promising approach to understand the relationship between the vast tumor microbiome and cancer development. In the present study, we studied the relationships between the intratumoral microbiome and classical clinical ri
Externí odkaz:
https://doaj.org/article/e93cdcbd94e94d90855a63d5c367babd
Autor:
Kaori Oya, Akinori Takeshita, Kanta Wakamori, Misa Song, Hayato Kimura, Katsutoshi Hirose, Hiroaki Shimamoto, Sunao Sato, Kazuhide Matsunaga, Narikazu Uzawa, Satoru Toyosawa
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Background Cementoblastoma is a rare odontogenic tumor characterized by the formation of osteocementum-like tissue on a tooth root directly by neoplastic cementoblasts. Although it is categorized as benign, it has a high potential for growth
Externí odkaz:
https://doaj.org/article/29ebbef0b29a4073b3fd98e2d218c4b2
Autor:
Kanako Tokuda, Shiou-Ling Lu, Zidi Zhang, Yumiko Kato, Siyu Chen, Kazuya Noda, Katsutoshi Hirose, Yu Usami, Narikazu Uzawa, Shinya Murakami, Satoru Toyosawa, Mitsunori Fukuda, Ge-Hong Sun-Wada, Yoh Wada, Takeshi Noda
Publikováno v:
Cell Structure and Function, Vol 48, Iss 2, Pp 223-239 (2023)
Osteoclasts play a crucial role in bone homeostasis by forming resorption pits on bone surfaces, resulting in bone resorption. The osteoclast expression of Rab38 protein is highly induced during differentiation from macrophages. Here we generated mic
Externí odkaz:
https://doaj.org/article/e7d62b5bd39e4e2782739301d81a6565
Publikováno v:
Journal of Dental Sciences, Vol 18, Iss 3, Pp 991-996 (2023)
Background/purpose: In lower third molar (LM3) surgery, panoramic radiography (PAN) is important for the initial assessment of the anatomical association between LM3 and the inferior alveolar nerve (IAN). This study aimed to develop a deep learning m
Externí odkaz:
https://doaj.org/article/fcf2e07528a14eb1aa48e196ce7b8dc0
Autor:
Takayuki Kosaka, Masahiro Wada, Suzuna Akema, Yuichi Nishimura, Kazuhide Matsunaga, Narikazu Uzawa, Kazunori Ikebe
Publikováno v:
International Journal of Implant Dentistry, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Background The extensive loss of teeth and surrounding tissues due to mandibulectomy for an oral tumor not only impacts negatively on appearance, but also often causes various functional disorders, decreasing quality of life (QOL). In the pr
Externí odkaz:
https://doaj.org/article/1c34ad9a97f6481a9183c8813e4ec439
Autor:
Shota Ishihara, Kenji Hata, Katsutoshi Hirose, Tatsuo Okui, Satoru Toyosawa, Narikazu Uzawa, Riko Nishimura, Toshiyuki Yoneda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Metabolic reprogramming is a malignant phenotype of cancer. Cancer cells utilize glycolysis to fuel rapid proliferation even in the presence of oxygen, and elevated glycolysis is coupled to lactate fermentation in the cancer microenvironment
Externí odkaz:
https://doaj.org/article/cfb73f1b70b14fa58f27af5a6bfb900e
Autor:
Masakazu Hamada, Hiroaki Inaba, Kyoko Nishiyama, Sho Yoshida, Yoshiaki Yura, Michiyo Matsumoto-Nakano, Narikazu Uzawa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15456 (2023)
The tumor microbiome, a relatively new research field, affects tumor progression through several mechanisms. The Cancer Microbiome Atlas (TCMA) database was recently published. In the present study, we used TCMA and The Cancer Genome Atlas and examin
Externí odkaz:
https://doaj.org/article/0cdeb8d428c54bcf903a5f05ef412be9
Publikováno v:
FEBS Open Bio, Vol 12, Iss 2, Pp 460-469 (2022)
The transcription factor, hypoxia‐inducible factor‐1α (HIF‐1α), has previously been shown to upregulate the expression of hypoxia‐related genes, including erythropoietin (EPO). However, the role of hypoxia‐inducible factor‐1α in morpho
Externí odkaz:
https://doaj.org/article/3267a8e1d1e048d9b270982c40120f54
Autor:
Masakazu Hamada, Hiroaki Inaba, Kyoko Nishiyama, Sho Yoshida, Yoshiaki Yura, Michiyo Matsumoto-Nakano, Narikazu Uzawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Autophagy-related genes (ARGs) have been implicated in the initiation and progression of malignant tumor promotion. To investigate the dynamics of expression of genes, including ARGs, head and neck squamous cell carcinoma (HNSCC) cells were
Externí odkaz:
https://doaj.org/article/50ccf741aa1c4cac93bd87c7a353cb38