Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nari Ryu"'
Autor:
Min-A Kim, Nari Ryu, Hye-Min Kim, Ye-Ri Kim, Byeonghyeon Lee, Tae-Jun Kwon, Jinwoong Bok, Un-Kyung Kim
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 197-204 (2019)
Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to the different cell type-specific functions. Adeno-associated virus (AAV) is an efficient in vivo gene transfer vector, and it has demonstra
Externí odkaz:
https://doaj.org/article/b7c1714cb9374824b6a5cf08af193951
Autor:
Ye-Ri Kim, Jeong-In Baek, Sung Hwan Kim, Min-A Kim, Byeonghyeon Lee, Nari Ryu, Kyung-Hee Kim, Deok-Gyun Choi, Hye-Min Kim, Michael P. Murphy, Greg Macpherson, Yeon-Sik Choo, Jinwoong Bok, Kyu-Yup Lee, Jeen-Woo Park, Un-Kyung Kim
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 544-555 (2019)
Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) is a major NADPH-producing enzyme which is essential for maintaining the mitochondrial redox balance in cells. We sought to determine whether IDH2 deficiency induces mitochondrial dysfun
Externí odkaz:
https://doaj.org/article/d71b374266564676820b6c5f775c1afa
Publikováno v:
Gene. 703:83-90
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has ushered in a new era of gene therapy. In this study, we aimed to demonstrate precise CRISPR/Cas9-mediated genome editing of the splicing mutation c.919-2A > G in intro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdc1858a2cfc970d1d5640813dd567c
https://doi.org/10.1016/j.gene.2019.03.020
https://doi.org/10.1016/j.gene.2019.03.020
Autor:
Un-Kyung Kim, Nari Ryu, Tae-Jun Kwon, Min-A Kim, Byeonghyeon Lee, Jinwoong Bok, Hye-Min Kim, Ye-Ri Kim
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 197-204 (2019)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to the different cell type-specific functions. Adeno-associated virus (AAV) is an efficient in vivo gene transfer vector, and it has demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa613e9a30295941d09c96f8aaf0d0a
http://www.sciencedirect.com/science/article/pii/S2329050119300051
http://www.sciencedirect.com/science/article/pii/S2329050119300051
Autor:
Jinwoong Bok, Ji-Hyun Ma, Kyu-Yup Lee, Jae Young Choi, Jinsei Jung, Min-A Kim, Ye-Ri Kim, Philine Wangemann, Nari Ryu, Sung Huhn Kim, Un-Kyung Kim, Chuan-Jen Hsu
Publikováno v:
Theranostics
Rationale: Mutations of SLC26A4 that abrogate pendrin, expressed in endolymphatic sac, cochlea and vestibule, are known to cause autosomal recessive sensorineural hearing loss with enlargement of the membranous labyrinth. This is the first study to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69635f50c56806c6c7690e6abc34c496
https://doi.org/10.7150/thno.38032
https://doi.org/10.7150/thno.38032
Autor:
Byeonghyeon Lee, Jeong-In Baek, Kyu-Yup Lee, Won Jong Kim, Dongsik Park, Min-A Kim, Kyung-Hee Kim, Ye-Ri Kim, Un-Kyung Kim, Nari Ryu
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 14:2095-2102
The-state-of-art CRISPR/Cas9 is one of the most powerful among the approaches being developed to rescue fundamental causes of gene-based inheritable diseases. Several strategies for delivering such genome editing materials have been developed, but th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8802205ab5fe14727a06b513f7a78f21
https://doi.org/10.1016/j.nano.2018.06.009
https://doi.org/10.1016/j.nano.2018.06.009
Autor:
Hong-Joon Park, Jinwoong Bok, Byeonghyeon Lee, Seokwon Lee, Chan Ik Park, Tae-Jun Kwon, Kyu-Yup Lee, Jeong-In Baek, Un-Kyung Kim, Nari Ryu
Publikováno v:
Gene. 627:233-238
Hereditary hearing loss (HHL) is a common genetically heterogeneous disorder, which follows Mendelian inheritance in humans. Because of this heterogeneity, the identification of the causative gene of HHL by linkage analysis or Sanger sequencing have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb94d659650fad927f706f0ed42c59c
https://doi.org/10.1016/j.gene.2017.06.040
https://doi.org/10.1016/j.gene.2017.06.040
Autor:
Nari Ryu1, Borum Sagong1, Hong-Joon Park2, Min-A Kim1,3, Kyu-Yup Lee4, Jae Young Choi5, Un-Kyung Kim1,3 kimuk@knu.ac.kr
Publikováno v:
BMC Medical Genetics. 1/22/2016, Vol. 17, p1-6. 6p.
Autor:
Sung Hwan Kim, Kyung-Hee Kim, Ye-Ri Kim, Greg Macpherson, Hye-Min Kim, Min-A Kim, Kyu-Yup Lee, Nari Ryu, Jeong-In Baek, Un-Kyung Kim, Byeonghyeon Lee, Deok-Gyun Choi, Michael P. Murphy, Yeon-Sik Choo, Jeen-Woo Park, Jinwoong Bok
Publikováno v:
Redox Biology
Redox Biology, Vol 20, Iss, Pp 544-555 (2019)
Redox Biology, Vol 20, Iss, Pp 544-555 (2019)
Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) is a major NADPH-producing enzyme which is essential for maintaining the mitochondrial redox balance in cells. We sought to determine whether IDH2 deficiency induces mitochondrial dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7483e151e78b0d6ef0d79fd33ed338
https://pubmed.ncbi.nlm.nih.gov/30508699
https://pubmed.ncbi.nlm.nih.gov/30508699
Publikováno v:
BMC MEDICAL GENETICS(17)
BMC Medical Genetics
BMC Medical Genetics
Background: One of the causes of sensorineural hearing loss (SNHL) is degeneration of the inner hair cells in the organ of Corti in the cochlea. The SLC17A8 (solute carrier family 17, member 8) gene encodes vesicular glutamate transporter 3 (VGLUT3),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec023d5cb43abb4500990473a2beb1ee
http://open-repository.kisti.re.kr/cube/handle/open_repository/484539.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/484539.do
