Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Narges, Aghaallaei"'
Autor:
Bianca Walter, Sophie Hirsch, Laurence Kuhlburger, Aaron Stahl, Leonard Schnabel, Silas Wisser, Lara A. Haeusser, Foteini Tsiami, Sarah Plöger, Narges Aghaallaei, Advaita M Dick, Julia Skokowa, Christian Schmees, Markus Templin, Katja Schenke-Layland, Marcos Tatagiba, Sven Nahnsen, Daniel J. Merk, Ghazaleh Tabatabai
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background The DNA damage response (DDR) is a physiological network preventing malignant transformation, e.g. by halting cell cycle progression upon DNA damage detection and promoting DNA repair. Glioblastoma are incurable primary tumors of
Externí odkaz:
https://doaj.org/article/facd8d65569547ca88e803ac3908a694
Autor:
Larissa Doll, Narges Aghaallaei, Claudia Lengerke, Cornelia Zeidler, Karl Welte, Julia Skokowa, Baubak Bajoghli
Publikováno v:
HemaSphere, Vol 7, p e69758f3 (2023)
Externí odkaz:
https://doaj.org/article/0998c5acdfa0430593af8d5ae2f26bd2
Publikováno v:
HemaSphere, Vol 7, p e25600fc (2023)
Externí odkaz:
https://doaj.org/article/35ea6f56fa6746d4bd94d4360f2bf2c3
Autor:
Julia Skokowa, Birte Hernandez Alvarez, Murray Coles, Malte Ritter, Masoud Nasri, Jérémy Haaf, Narges Aghaallaei, Yun Xu, Perihan Mir, Ann-Christin Krahl, Katherine W. Rogers, Kateryna Maksymenko, Baubak Bajoghli, Karl Welte, Andrei N. Lupas, Patrick Müller, Mohammad ElGamacy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Skokowa et al. reconstruct the fold of a granulopoietic cytokine, resulting in de novo, hyperstable, highly active proteins with therapeutic potential for treating several neutropenia disorders.
Externí odkaz:
https://doaj.org/article/68deee8b6ece4f268cc8599f9cf0df38
Autor:
Narges Aghaallaei, Rashi Agarwal, Joergen Benjaminsen, Katharina Lust, Baubak Bajoghli, Joachim Wittbrodt, Carmen G. Feijoo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Organized intestinal mucosal immune response appears to be restricted to tetrapods. In teleost fish, there is no evidence for the existence of a particular intestinal region that facilitates the interaction of antigen-presenting cells (APCs) and T ce
Externí odkaz:
https://doaj.org/article/d7733bfe9d6e446384013d795e247b0a
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Severe congenital neutropenia (CN) is a rare heterogeneous group of diseases, characterized by a granulocytic maturation arrest. Autosomal recessive mutations in the HAX1 gene are frequently detected in affected individuals. However, the precise role
Externí odkaz:
https://doaj.org/article/df6abd2cbb374869b7db564f38bcbe21
Autor:
Masoud Nasri, Malte Ritter, Perihan Mir, Benjamin Dannenmann, Narges Aghaallaei, Diana Amend, Vahagn Makaryan, Yun Xu, Breanna Fletcher, Regine Bernhard, Ingeborg Steiert, Karin Hahnel, Jürgen Berger, Iris Koch, Brigitte Sailer, Katharina Hipp, Cornelia Zeidler, Maksim Klimiankou, Baubak Bajoghli, David C. Dale, Karl Welte, Julia Skokowa
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
A Autosomal-dominant ELANE mutations are the most common cause of severe congenital neutropenia. Although the majority of congenital neutropenia patients respond to daily granulocyte colony stimulating factor, approximately 15 % do not respond to thi
Externí odkaz:
https://doaj.org/article/69e87326290b4238bf136d667edcfb2f
Autor:
Gerlinde Doenz, Sebastian Dorn, Narges Aghaallaei, Baubak Bajoghli, Elisabeth Riegel, Michaela Aigner, Holger Bock, Birgit Werner, Thomas Lindhorst, Thomas Czerny
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene inactivation in vivo. We recently introduced phosphonic ester modified peptide nucleic acids (PNA) for in vivo loss-of-fun
Externí odkaz:
https://doaj.org/article/ebcc5c44420f40ddbd3a7bce3da58446
Autor:
Narges Aghaallaei, Baubak Bajoghli
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T-cell development is coupled with a highly ordered migratory pattern. Lymphoid progenitors must follow a precise journey; starting from the hematopoietic tissue, they move toward the thymus and then migrate into and out of distinct thymic microenvir
Externí odkaz:
https://doaj.org/article/10ede3b5dd584dff89b287fd1279061c
Publikováno v:
Haematologica
Severe congenital neutropenia is a rare heterogeneous group of diseases, characterized by an arrest of granulocyte maturation. Autosomal recessive mutations in the HAX1 gene are frequently detected in affected individuals. However, the precise role o