Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Naresh Pavurala"'
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 12, Iss 6, Pp 532-541 (2017)
Polysaccharide-based polymers were used to produce nanoparticles of poorly soluble antiviral drugs using a rapid precipitation process. The structure-property relationships of four novel cellulose acetate-based polymers were studied for their solubil
Externí odkaz:
https://doaj.org/article/8aec95075d4b42fca4e1f33ac815efe4
Publikováno v:
Chemical Engineering Research and Design. 190:10-19
Publikováno v:
Current Pharmaceutical Analysis. 18:694-703
Background: Transdermal drug delivery systems (TDS) are widely used to deliver a number of different drug therapeutics. The design delivery can be impacted by excipients and, more broadly, organic solvents. Organic or residual solvents are routinely
Autor:
Adil Mohammad, Naresh Pavurala, Wei-Lee Wu, Xiaochuan Yang, Thomas F. O’Connor, David Acevedo
Publikováno v:
CrystEngComm. 23:972-985
Pharmaceutical crystallization has an impact on the properties of active pharmaceutical ingredients as it determines the purity, crystal size distribution and polymorphs, among other attributes. Focused beam reflectance measurement (FBRM) is a common
Autor:
Yiqing C. Liu, David Acevedo, Thomas F. O’Connor, Xiaochuan Yang, Zoltan K. Nagy, Wei-Lee Wu, Sean Naimi, Naresh Pavurala
Publikováno v:
Crystal Growth & Design. 20:5235-5250
Using process modeling to understand process dynamics and potentially explore the design space of a crystallization process is difficult because of its complex nature with many factors at play, suc...
Autor:
Sara Mattson, Diaa Shakleya, Muhammad Ashraf, Patrick J. Faustino, Sonal Mazumder, Naresh Pavurala
Publikováno v:
International journal of pharmaceutics. 588
The purpose of this investigation was to systematically assess the effect of residual solvents on the physical properties of a silicone adhesive-based transdermal system (TDS) containing n-heptane and o-xylene as residual solvents. The processing tem
Autor:
Haiou Qu, Marilyn N. Martinez, Vasanthakumar Sekar, Muhammad Ashraf, Xiaoming Xu, Jiang Wang, Raafat Fahmy, Celia N. Cruz, Naresh Pavurala, Yixuan Dong
Publikováno v:
International Journal of Pharmaceutics. 544:254-264
The aim of the present study was to investigate the relationship between formulation/process variables versus the critical quality attributes (CQAs) of cyclosporine ophthalmic ointments and to explore the feasibility of using an in vitro approach to
Autor:
Celia N. Cruz, Xiaochuan Yang, Thomas F. O’Connor, Zoltan K. Nagy, Naresh Pavurala, Wei-Lee Wu, Adil Mohammad, David Acevedo
Publikováno v:
Organic Process Research & Development. 22:156-165
Crystallization has a significant impact on the properties of the active pharmaceutical ingredient (API) since it is the final step in the manufacturing of the drug substance and determines particle size distribution, purity, shape, and polymorphs. M
Publikováno v:
Journal of Drug Delivery Science and Technology. 41:269-279
Rheumatoid Arthritis is a destructive illness and results in damage of joints and cartilages, followed by loss of function. Curcumin proved to be more effective in alleviating the symptoms of rheumatoid arthritis like tenderness and swelling of joint
Autor:
Adil Mohammad, David Acevedo, Mark J. Goldman, Alexander L. Brayton, Xiaochuan Yang, Thomas F. O’Connor, Shuaili Li, Fan He, Robert J. Fisher, Huiquan Wu, Celia N. Cruz, Ryan Shaw, Naresh Pavurala
Publikováno v:
Organic Process Research & Development. 21:1021-1033
Continuous manufacturing (CM) is an emerging technology in the pharmaceutical manufacturing sector, and the understanding of the impact on product quality is currently evolving. As the final purification and isolation step, crystallization has a sign