Výsledky vyhledávání - "Naresh C. Sahoo"

A novel mechanism for ERK-dependent regulation of IL4 transcription during human Th2-cell differentiation

Autor: Parul Tripathi, Henna Kallionpää, Kanury V. S. Rao, Riitta Lahesmaa, Ubaid Ullah, Naresh C. Sahoo, Amita Suneja

Publikováno v: Immunology and Cell Biology; Vol 90
Immunology and Cell Biology

We demonstrate that the mitogen-activated protein kinases extracellular signal-regulated kinase (ERK)-1 and ERK-2 have a central role in mediating T-cell receptor-dependent induction of IL4 expression in human CD4(+) T cells. Significantly, this invo

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Regulation of Transcript Elongation through Cooperative and Ordered Recruitment of Cofactors

Autor: Kanury V. S. Rao, Manish Sharma, Anuja A. George, Badri Nath Singh, Naresh C. Sahoo

Publikováno v: Journal of Biological Chemistry. 282:20887-20896

We studied the regulation of murine CD80, a gene whose basal transcriptional status was characterized by the presence of a stalled RNA polymerase II complex on the promoter-proximal region. Stimulus-induced activation of productive elongation involve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0d2efdd27abc44ad4adb6c178102e5
https://doi.org/10.1074/jbc.m701420200

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Transcription regulation from a TATA and INR-less promoter: spatial segregation of promoter function

Autor: Badri Nath Singh, Naresh C. Sahoo, Manish Sharma, Anuja A. George, Kanury V. S. Rao

Publikováno v: The EMBO Journal. 25:811-821

The mode of regulation of class II genes that lack the known core promoter elements is presently unclear. Here, we studied one such example, the murine CD80 gene. An unusual mechanism was revealed wherein the pre-initiation complex (PIC) first assemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4a11dbbffd29878f696fdb682c470d
https://doi.org/10.1038/sj.emboj.7600966

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Dynamic Regulation of Nucleosome for Detection of CD80 Gene Expression in Murine

Autor: K Vivehananthan, Naresh C. Sahoo, Manish Sharma, Kvs Ram Rao

Publikováno v: Journal of Food and Agriculture. 3

The basic building blocks of chromatin are referred to as the nucleosome. Nucleosomes play major role in transcriptional regulation, ranging from repression through occlusion of binding sites for transcription factors, to activation through spatial j

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::faeab71d417b4dc07c96f65967aa67c4
https://doi.org/10.4038/jfa.v3i1-2.5166

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Signal thresholds and modular synergy during expression of costimulatory molecules in B lymphocytes

Autor: Naresh C. Sahoo, Krishnamurthy Natarajan, Kanury V. S. Rao

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 167(1)

We analyzed intracellular pathways modulating surface densities of CD80 and CD86 in B cells activated through ligation of the Ag receptor, and the adhesion molecule CD54. Whereas B cell Ag receptor (BCR) cross-linking alone stimulated increased expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64535565a64b198487a0780080807a9
https://pubmed.ncbi.nlm.nih.gov/11418639

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Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

Autor: Naresh C. Sahoo, Kanury V. S. Rao, Venkatasamy Manivel, Dinakar M. Salunke

Publikováno v: Immunity. 13(5)

Although affinity maturation constitutes an integral part of T-dependent humoral responses, its structural basis is less well understood. We compared the physicochemical properties of antigen binding of several independent antibody panels derived fro

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https://pubmed.ncbi.nlm.nih.gov/11114374

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A novel 70-kDa Triton X-114-soluble antigen of Plasmodium falciparum that contains interspecies-conserved epitopes

Autor: Pradeep Das, Vijaya Dhanda, Lalit K. Das, Balwan Singh, Pratima Ray, Fred A.S. Kironde, Kailash P. Patra, Naresh C. Sahoo, Seema Paliwal, Hui Wen Ma

Publikováno v: Experimental parasitology. 83(3)

M a , H. W., R ay , P., D handa , V., D as , P. K., P aliwal , S., S ahoo , N., P atra , K. P., D as , L. K., S ingh , B., and K ironde , F. A. S. 1996. A novel 70-kDa Triton X-114-soluble antigen of Plasmodium falciparum that contains interspecies-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a67fbf803f7db8be52b01adbcab194
https://pubmed.ncbi.nlm.nih.gov/8823249

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Serum antibody immunoglobulin G of mice convalescent from Plasmodium yoelii infection inhibits growth of Plasmodium falciparum in vitro: blood stage antigens of P. falciparum involved in interspecies cross-reactive inhibition of parasite growth

Autor: Naresh C. Sahoo, Pratima Ray, F. A. S. Kironde, Balwan Singh

Publikováno v: Scopus-Elsevier

We demonstrated that antibodies in the serum of BALB/c mice convalescent from Plasmodium yoelii infection inhibit the in vitro growth of Plasmodium falciparum. Blood stage P. falciparum antigens that cross-react with the convalescent-phase mouse seru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed6dc87b7986dd37fd03b88f61390c8
https://europepmc.org/articles/PMC186518/

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