Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Naresh Babu V. Sepuri"'
Autor:
Noble Kumar Talari, Ushodaya Mattam, Niroj Kumar Meher, Arun Kumar Paripati, Kalyankar Mahadev, Thanuja Krishnamoorthy, Naresh Babu V. Sepuri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
How the liver mitochondria seamlessly regulate lipogenesis and lipid oxidation is unknown. Here, the authors report two functionally distinct populations of mitochondria, cytoplasmic and lipid droplet-associated mitochondria, and demonstrate that the
Externí odkaz:
https://doaj.org/article/26a5ccc1719244d08a9ef1f7ea54dbe9
Autor:
Venkata Ramana Thiriveedi, Ushodaya Mattam, Prasad Pattabhi, Vandana Bisoyi, Noble Kumar Talari, Thanuja Krishnamoorthy, Naresh Babu V. Sepuri
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101725- (2020)
Human MIA40, an intermembrane space (IMS) import receptor of mitochondria harbors twin CX9C motifs for stability while its CPC motif is known to facilitate the import of IMS bound proteins. Site-directed mutagenesis complemented by MALDI on in vivo h
Externí odkaz:
https://doaj.org/article/774bd0baec2c45848b29a61f383f5322
Publikováno v:
The FEBS Journal. 288:5737-5754
Mitochondrial dysfunction mediated by CCCP (carbonyl cyanide m-chlorophenyl hydrazone), an inhibitor of mitochondrial oxidative phosphorylation, evokes the integrated stress response (ISR), which is analyzed here by eIF2α phosphorylation and express
The transcription factor NF-κB regulates a large array of genes of immune and inflammatory responses. Deregulated NF-κB signalling is implicated in the pathogenesis and broad spectrum of human inflammatory disorders and malignancies. The mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6af14043667e417e92369eb204468b58
https://doi.org/10.21203/rs.3.rs-941317/v1
https://doi.org/10.21203/rs.3.rs-941317/v1
Autor:
Amita Pal, Arun Kumar Paripati, Pallavi Deolal, Arpan Chatterjee, Pushpa Rani Prasad, Priyanka Adla, Naresh Babu V. Sepuri
Publikováno v:
Journal of Biological Chemistry. 298:102533
Mitochondrial morphology and dynamics maintain mitochondrial integrity by regulating its size, shape, distribution, and connectivity, thereby modulating various cellular processes. Several studies have established a functional link between mitochondr
Autor:
Ushodaya Mattam, Mohammed Fareed, Kalyankar Mahadev, Naresh Babu V. Sepuri, Sathya Velmurugan, Noble Kumar Talari, Venkata Ramana Thiriveedi
Publikováno v:
Exp Ther Med
Aging leads to the diminished pulsatile secretion of hypothalamic gonadotropin-releasing hormone (GnRH). Kisspeptin (Kp), the upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis, regulates GnRH synthesis and release through its cognat
Autor:
Arun Kumar Paripati, Thanuja Krishnamoorthy, Adinarayana Marada, Srinivasu Karri, Swati Singh, Lalitha Guruprasad, Naresh Babu V. Sepuri, Dorairajan Balasubramanian
Publikováno v:
Mitochondrion. 46:140-148
Perturbations in mitochondrial redox levels oxidize nucleotide exchanger Mge1, compromising its ability to bind to the Hsp70, while the Mxr2 enzyme reduces the oxidized Mge1. However, the effects of persistent oxidative stress on Mge1 structure and f
Autor:
Katyayani Mallick, Arcy Billoria, Fareed Mohammed, Naresh Babu V. Sepuri, Ushodaya Mattam, Arpan Chatterjee, Deepika Rathore, Lekha Gandhi, Musturi Venkataramana, Deepti Maisnam, V. S. V. Prasad, Chaitanya Gandikota
Publikováno v:
J Virol
Dengue virus infections, which have been reported in nearly 140 countries, pose a significant threat to human health. The genome of dengue virus encodes three structural and seven nonstructural (NS) proteins along with two untranslated regions, one e