Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Narese/8"'
Autor:
Sarah Adi Eisdorfer, Morya Ifrach, Stefan Ilic, Dan Vilenchik, Ariel Afek, Barak Akabayov, Adam Soffer, Hallel Schussheim
Publikováno v:
Nucleic Acids Research
DNA–protein interactions play essential roles in all living cells. Understanding of how features embedded in the DNA sequence affect specific interactions with proteins is both challenging and important, since it may contribute to finding the means
Autor:
Douglas J. Hartman, Zengbiao Qi, Hatice U. Osmanbeyoglu, Harinder Singh, Xiaojun Ma, Ashwin Somasundaram
Publikováno v:
Nucleic Acids Research
The identity and functions of specialized cell types are dependent on the complex interplay between signaling and transcriptional networks. Recently single-cell technologies have been developed that enable simultaneous quantitative analysis of cell-s
Autor:
Yves Mély, Hoang Ngoan Le, Steve Vincent, Janah Shaya, Benoît Y. Michel, Ludovic Richert, Vincent Guérineau, Alain Burger, Guillaume Barnoin
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (12), pp.e72-e72. ⟨10.1093/nar/gkab237⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (12), pp.e72-e72. ⟨10.1093/nar/gkab237⟩
The sensitivity of FRET-based sensing is usually limited by the spectral overlaps of the FRET donor and acceptor, which generate a poor signal-to-noise ratio. To overcome this limitation, a quenched donor presenting a large Stokes shift can be combin
Autor:
Tunca Doğan, Heval Atas, Ahmet Sureyya Rifaioglu, Maria Jesus Martin, Rabie Saidi, Rengul Cetin-Atalay, Hermann Zellner, Volkan Atalay, Vishal Joshi, Andrew Nightingale, Esra Nalbat, Ahmet Atakan, Vladimir Volynkin
Publikováno v:
Nucleic Acids Research
Systemic analysis of available large-scale biological/biomedical data is critical for studying biological mechanisms, and developing novel and effective treatment approaches against diseases. However, different layers of the available data are produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea230a7cafb20eeaf699870685fc865
https://hdl.handle.net/20.500.12508/1859
https://hdl.handle.net/20.500.12508/1859
Publikováno v:
Nucleic Acids Research
Classification of high-throughput genomic data is a powerful method to assign samples to subgroups with specific molecular profiles. Consensus partitioning is the most widely applied approach to reveal subgroups by summarizing a consensus classificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa7d72cdb6b1dfe6f7bf5b4e2530891
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/92399
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/92399
Publikováno v:
Nucleic Acids Research
In order to uncover the meanings of ‘book of life’, 155 different biological language models (BLMs) for DNA, RNA and protein sequence analysis are discussed in this study, which are able to extract the linguistic properties of ‘book of life’.
Autor:
Rei Kajitani, Takehiko Itoh, Atsushi Toyoda, Yasuhiro Gotoh, Dai Yoshimura, Hideki Noguchi, Yoshitoshi Ogura, Tomomi Kuwahara, Miki Okuno, Tetsuya Hayashi
Publikováno v:
Nucleic Acids Research
De novo metagenome assembly is effective in assembling multiple draft genomes, including those of uncultured organisms. However, heterogeneity in the metagenome hinders assembly and introduces interspecies misassembly deleterious for downstream analy
Publikováno v:
Nucleic Acids Research
In vitro aptamer isolation methods can yield hundreds of potential candidates, but selecting the optimal aptamer for a given application is challenging and laborious. Existing aptamer characterization methods either entail low-throughput analysis wit
Publikováno v:
Nucleic Acids Research
Mass spectrometry (MS)-based quantitative proteomics experiments frequently generate data with missing values, which may profoundly affect downstream analyses. A wide variety of imputation methods have been established to deal with the missing-value
Autor:
Peng Xu, Benjamin Demaree, Frederick F. Twigg, Cyrus Modavi, Benjamin Liang, Adam R. Abate, Chen Sun, Wenjun Zhang
Publikováno v:
Nucleic acids research, vol 48, iss 8
Nucleic Acids Research
Nucleic Acids Research
Microbial biosynthetic gene clusters are a valuable source of bioactive molecules. However, because they typically represent a small fraction of genomic material in most metagenomic samples, it remains challenging to deeply sequence them. We present