Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Narendran G-Dayanan"'
Autor:
Charles Giardina, Dennis L. Wright, Daniel W. Rosenberg, Santosh Keshipeddy, Narendran G-Dayanan, Masako Nakanishi, Eric W. Scocchera, Lauren E. Harrison, Marina Bleiler, Michael J. Bond
AK3 compounds are mitotic arrest agents that induce high levels of γH2AX during mitosis and apoptosis following release from arrest. We synthesized a potent AK3 derivative, AK306, that induced arrest and apoptosis of the HCT116 colon cancer cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e92d574068b140615bb01bbbeac9ec
https://doi.org/10.1158/1541-7786.c.6540373.v1
https://doi.org/10.1158/1541-7786.c.6540373.v1
Autor:
Charles Giardina, Dennis L. Wright, Daniel W. Rosenberg, Santosh Keshipeddy, Narendran G-Dayanan, Masako Nakanishi, Eric W. Scocchera, Lauren E. Harrison, Marina Bleiler, Michael J. Bond
S1: Results from AK306 testing on the NCI60 cancer cell line panel. Testing was done by the National Institutes of Health Developmental Therapeutics Program. S2: AK3-BODIPY arrests YAMC cells in mitosis at 600 and 800 nM. YAMCs were treated with comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40366d33a0cf6e0b72e472e57e097950
https://doi.org/10.1158/1541-7786.22512910.v1
https://doi.org/10.1158/1541-7786.22512910.v1
Autor:
Cecilia Gutierrez-Perez, Charles Puerner, Jane T. Jones, Sandeep Vellanki, Elisa M. Vesely, Mark A. Xatse, Andre F. C. Viera, Carissa P. Olsen, Keren O. Attiku, Steven Cardinale, Steven M. Kwasny, Narendran G-Dayanandan, Timothy J. Opperman, Robert A. Cramer
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against
Externí odkaz:
https://doaj.org/article/6c6f0dfdb29846f4968aadcda7933aa2
Autor:
Narendran G-Dayanan, Santosh Keshipeddy, Marina Bleiler, Eric W. Scocchera, Masako Nakanishi, Charles Giardina, Michael J Bond, Daniel W. Rosenberg, Lauren E Harrison, Dennis L. Wright
Publikováno v:
Molecular Cancer Research. 16:1361-1372
AK3 compounds are mitotic arrest agents that induce high levels of γH2AX during mitosis and apoptosis following release from arrest. We synthesized a potent AK3 derivative, AK306, that induced arrest and apoptosis of the HCT116 colon cancer cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a549e1806565af658a22e2a5ce11ad67
https://doi.org/10.1158/1541-7786.mcr-18-0178
https://doi.org/10.1158/1541-7786.mcr-18-0178
Autor:
Behnoush Hajian, Eric Scocchera, Santosh Keshipeddy, Narendran G-Dayanandan, Carolyn Shoen, Jolanta Krucinska, Stephanie Reeve, Michael Cynamon, Amy C Anderson, Dennis L Wright
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161740 (2016)
Mycobacterium tuberculosis continues to cause widespread, life-threatening disease. In the last decade, this threat has grown dramatically as multi- and extensively-drug resistant (MDR and XDR) bacteria have spread globally and the number of agents t
Externí odkaz:
https://doaj.org/article/efa43d29055a4aac8d2f815c84430a91