Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Narendra Padhan"'
Autor:
Xiujuan Li, Björn Redfors, Miguel Sáinz-Jaspeado, Shujing Shi, Pernilla Martinsson, Narendra Padhan, Margareta Scharin Täng, Jan Borén, Malin Levin, Lena Claesson-Welsh
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
AimThe acute phase of myocardial infarction (MI) is accompanied by edema contributing to tissue damage and disease outcome. Here, we aimed to identify the mechanism whereby vascular endothelial growth factor (VEGF)-A induces myocardial edema in the a
Externí odkaz:
https://doaj.org/article/86ee85b548794f66853e0d403d60833f
Autor:
Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Narendra Padhan, Jimmy Larsson, Maria Karoutsou, Kenneth Ban, Jacek R. Wiśniewski, Per Artursson, Liqun He, Mats Hellström, Tobias Sjöblom
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background The Ras pathway genes KRAS, BRAF, or ERBBs have somatic mutations in ~ 60% of human colorectal carcinomas. At present, it is unknown whether the remaining cases lack mutations activating the Ras pathway or whether they have acquir
Externí odkaz:
https://doaj.org/article/e59e8395c9b944bfa4183f634a16c9e7
Autor:
Narendra Padhan, Junhong Yan, Annegret Boge, Elaine Scrivener, Helgi Birgisson, Agata Zieba, Mats Gullberg, Masood Kamali-Moghaddam, Lena Claesson-Welsh, Ulf Landegren
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Detection and quantification of proteins and their post-translational modifications are crucial to decipher functions of complex protein networks in cell biology and medicine. Capillary isoelectric focusing together with antibody-based detec
Externí odkaz:
https://doaj.org/article/5fd5a922af6646128a84ed14eb0a59b9
Autor:
Xiujuan Li, Narendra Padhan, Elisabet O. Sjöström, Francis P. Roche, Chiara Testini, Naoki Honkura, Miguel Sáinz-Jaspeado, Emma Gordon, Katie Bentley, Andrew Philippides, Vladimir Tolmachev, Elisabetta Dejana, Radu V. Stan, Dietmar Vestweber, Kurt Ballmer-Hofer, Christer Betsholtz, Kristian Pietras, Leif Jansson, Lena Claesson-Welsh
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Signals through VEGF receptor 2 (VEGFR2) increase vascular permeability, promoting cancer progression. Here the authors show that a point mutation in VEGFR2 preventing its auto-phosphorylation leads to reduced metastatic spread and improved response
Externí odkaz:
https://doaj.org/article/b507e4a16cf547ee96f8120a0c5f0330
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96202 (2014)
The diversity of functions carried out by EF hand-containing calcium-binding proteins is due to various interactions made by these proteins as well as the range of affinity levels for Ca²⁺ displayed by them. However, accurate methods are not avail
Externí odkaz:
https://doaj.org/article/c66ac7c97e114588b575c33bd0ceddb1
Autor:
Sònia Tugues, Francis Roche, Oriol Noguer, Anna Orlova, Sujata Bhoi, Narendra Padhan, Peter Akerud, Satoshi Honjo, Ram Kumar Selvaraju, Massimiliano Mazzone, Vladimir Tolmachev, Lena Claesson-Welsh
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107483 (2014)
Histidine-rich glycoprotein (HRG) is implicated in tumor growth and metastasis by regulation of angiogenesis and inflammation. HRG is produced by hepatocytes and carried to tissues via the circulation. We hypothesized that HRG's tissue distribution a
Externí odkaz:
https://doaj.org/article/e3f723a623e34db3b807cc79329701a1
Autor:
Ludmila Elfineh, Ulf Martens, Ida-Maria Sintorn, Shimei Wee, Narendra Padhan, Sathishkumar Baskaran, Linnéa Schmidt, Maria Häggblad, Karin Forsberg-Nilsson, Bengt Westermark, Patrik Johansson, Ingrid Lönnstedt, Michael Andäng, Lydia C. Green, Lene Uhrbom, Sven Nelander, Lena Claesson-Welsh, Bo Lundgren, Damian J. Matuszewski, Cecilia Krona
Publikováno v:
Oncotarget
Glioblastoma multiforme (GBM, astrocytoma grade IV) is the most common malignant primary brain tumor in adults. Addressing the shortage of effective treatment options for this cancer, we explored repurposing of existing drugs into combinations with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a090c37376c7b084e8c6c8b00ddb8f5
https://doi.org/10.18632/oncotarget.12298
https://doi.org/10.18632/oncotarget.12298
Autor:
Narendra Padhan
Publikováno v:
J Vis Exp
Immunoblotting has become a routine technique in many laboratories for protein characterization from biological samples. The following protocol provides an alternative strategy, capillary isoelectric focusing (cIEF), with many advantages compared to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a1a7b35b8860249e4d282f75fb8e70
https://doi.org/10.3791/56794-v
https://doi.org/10.3791/56794-v
Autor:
Snehangshu Kundu, Ali, Muhammad, Handin, Niklas, Narendra Padhan, Larsson, Jimmy, Karoutsou, Maria, Ban, Kenneth, Wiśniewski, Jacek, Artursson, Per, Liqun He, Hellström, Mats, Sjöblom, Tobias
and Tables S1–S10 with legends. (PDF 9090 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5b616449ebc7a3d604b9f0336e2dc9
Publikováno v:
Cellular Microbiology. 15:2020-2033
Summary The genome of Entamoeba histolytica encodes several calcium binding proteins and those characterized thus far have been shown to participate predominantly in phagocytosis and endocytosis. Our study showed that EhCaBP6 has two EF-hand domains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88966a6c3d988fa02e63e5f6b259134e
https://doi.org/10.1111/cmi.12167
https://doi.org/10.1111/cmi.12167