Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Narendra N, Tandon"'
Autor:
Arend Bonen, Xiao-Xia Han, Narendra N. Tandon, Jan F.C. Glatz, James Lally, Laelie A. Snook, Joost J. F.P. Luiken
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 4, Pp 740-748 (2009)
There is doubt whether spontaneously hypertensive rats (SHR; North American strain) are null for fatty acid translocase (FAT/CD36). Therefore, we examined whether FAT/CD36 is expressed in heart, muscle, liver and adipose tissue in SHR. Insulin resist
Externí odkaz:
https://doaj.org/article/63781b0538d545c0aac19a006c3b8342
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 528-542 (2007)
This study investigates the role of the cytoplasmic C terminus of fatty acid translocase (FAT/CD36) in localization of the molecule to the plasma membrane, its insertion into lipid rafts, and its ability to enhance long-chain fatty acid uptake in tra
Externí odkaz:
https://doaj.org/article/d01e83b67ca9451091c39287786e32ed
Autor:
Huzoor Akbar, Xun Shang, Rehana Perveen, Mark Berryman, Kevin Funk, James F Johnson, Narendra N Tandon, Yi Zheng
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22117 (2011)
Cdc42 and Rac1, members of the Rho family of small GTPases, play critical roles in actin cytoskeleton regulation. We have shown previously that Rac1 is involved in regulation of platelet secretion and aggregation. However, the role of Cdc42 in platel
Externí odkaz:
https://doaj.org/article/dda3a05306704fe591e828d8574bfc82
Publikováno v:
Transfusion. 53:100S-106S
BACKGROUND: Uncontrolled hemorrhage is responsible for ~80% of the potentially survivable deaths in combat and over 40% of early mortality in the under 65 age group in the United States. Providing an easily used infusible hemostatic agent to first re
Autor:
Sergio Grinstein, Nicolas Touret, Hirotaka Kuwata, William S. Trimble, Narendra N. Tandon, Richard F. Collins
Publikováno v:
Journal of Biological Chemistry. 284:30288-30297
The class B scavenger receptor CD36 has numerous ligands that include modified forms of low density lipoprotein, fibrillar amyloid, apoptotic cells, and Plasmodium falciparum-infected red blood cells, linking this molecule to atherosclerosis, Alzheim
Autor:
Arend Bonen, Carley R. Benton, Graham P. Holloway, Joost J.F.P. Luiken, Lawrence L. Spriet, Narendra N. Tandon, Jan F. C. Glatz, S. E. Campbell, Yuko Yoshida
Publikováno v:
The Journal of Physiology. 586:1755-1766
Peroxisome proliferator-activated receptors (PPARs) alter the expression of genes involved in regulating lipid metabolism. Rosiglitazone, a PPARγ agonist, induces tissue-specific effects on lipid metabolism; however, its mode of action in skeletal m
Autor:
Narendra N. Tandon, Arend Bonen, A. Brianne Thrush, David J. Dyck, Graham P. Holloway, George J. F. Heigenhauser, Lawrence L. Spriet
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 292:E1782-E1789
A reduction in fatty acid oxidation has been associated with lipid accumulation and insulin resistance in the skeletal muscle of obese individuals. We examined whether this decrease in fatty acid oxidation was attributable to a reduction in muscle mi
Autor:
Xiaoqi Gong, Hisao Takizawa, Keiji Okuyama, Michinori Tanaka, Narendra N. Tandon, Masuhiro Yoshitake, Sang Le, Yutaka Matsumoto, Jun-ichi Kambayashi, Simon Lockyer
Publikováno v:
Thrombosis Research. 119:319-329
Recent progress in the understanding of thrombus formation has suggested an important role for glycoprotein (GP) VI in this process. To clarify the exact role in detail, it is necessary to use specific, high affinity inhibitory antibodies. However, p
Autor:
Adrian Chabowski, Jorge Calles-Escandon, John C. Chatham, Narendra N. Tandon, Jan F. C. Glatz, Joost J. F. P. Luiken, Arend Bonen
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 291:E675-E682
An increased rate of fatty acid transport into skeletal muscle has been has been linked to the accumulation of intramuscular lipids and insulin resistance, and red muscles are more susceptible than white muscles in developing fatty acid-mediated insu
Publikováno v:
FEBS Letters. 580:3617-3623
Protein-mediated LCFA transport across plasma membranes is highly regulated by the fatty acid transporters FAT/CD36 and FABPpm. Physiologic stimuli (insulin stimulation, AMP kinase activation) induce the translocation of one or both transporters to t