Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nardus Mollentze"'
Autor:
Timothée Poisot, Marie-Andrée Ouellet, Nardus Mollentze, Maxwell J. Farrell, Daniel J. Becker, Liam Brierley, Gregory F. Albery, Rory J. Gibb, Stephanie N. Seifert, Colin J. Carlson
Publikováno v:
Patterns, Vol 4, Iss 6, Pp 100738- (2023)
Summary: Predicting host-virus interactions is fundamentally a network science problem. We develop a method for bipartite network prediction that combines a recommender system (linear filtering) with an imputation algorithm based on low-rank graph em
Externí odkaz:
https://doaj.org/article/e02f1f1e867240659707eee8533d0e1b
Autor:
Elena Sugrue, Arthur Wickenhagen, Nardus Mollentze, Muhamad Afiq Aziz, Vattipally B Sreenu, Sven Truxa, Lily Tong, Ana da Silva Filipe, David L Robertson, Joseph Hughes, Suzannah J Rihn, Sam J Wilson
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010973 (2022)
HIV-1 transmission via sexual exposure is an inefficient process. When transmission does occur, newly infected individuals are colonized by the descendants of either a single virion or a very small number of establishing virions. These transmitted fo
Externí odkaz:
https://doaj.org/article/312eb46f19e0404c960c54ff41b6efb3
Publikováno v:
eLife, Vol 11 (2022)
Transmission of SARS-CoV-2 from humans to other species threatens wildlife conservation and may create novel sources of viral diversity for future zoonotic transmission. A variety of computational heuristics have been developed to pre-emptively ident
Externí odkaz:
https://doaj.org/article/33d30546932b482bb5f605539676305e
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001390 (2021)
Determining which animal viruses may be capable of infecting humans is currently intractable at the time of their discovery, precluding prioritization of high-risk viruses for early investigation and outbreak preparedness. Given the increasing use of
Externí odkaz:
https://doaj.org/article/7b610add7e994491b0b4d404eb5c74b2
Autor:
Andrew E Shaw, Suzannah J Rihn, Nardus Mollentze, Arthur Wickenhagen, Douglas G Stewart, Richard J Orton, Srikeerthana Kuchi, Siddharth Bakshi, Mila Rodriguez Collados, Matthew L Turnbull, Joseph Busby, Quan Gu, Katherine Smollett, Connor G G Bamford, Elena Sugrue, Paul C D Johnson, Ana Filipe Da Silva, Alfredo Castello, Daniel G Streicker, David L Robertson, Massimo Palmarini, Sam J Wilson
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001352 (2021)
Antiviral defenses can sense viral RNAs and mediate their destruction. This presents a challenge for host cells since they must destroy viral RNAs while sparing the host mRNAs that encode antiviral effectors. Here, we show that highly upregulated int
Externí odkaz:
https://doaj.org/article/93c6a324bb0649b4bf2748908f349e90
Autor:
Laura M. Bergner, Nardus Mollentze, Richard J. Orton, Carlos Tello, Alice Broos, Roman Biek, Daniel G. Streicker
Publikováno v:
Viruses, Vol 13, Iss 2, p 252 (2021)
The contemporary surge in metagenomic sequencing has transformed knowledge of viral diversity in wildlife. However, evaluating which newly discovered viruses pose sufficient risk of infecting humans to merit detailed laboratory characterization and s
Externí odkaz:
https://doaj.org/article/a3935416752c499d951ddf245c8f1605
Autor:
Diana K. Meza, Nardus Mollentze, Alice Broos, Carlos Tello, William Valderrama, Sergio Recuenco, Jorge E. Carrera, Carlos Shiva, Nestor Falcon, Mafalda Viana, Daniel G. Streicker
The pathogen transmission dynamics in bat reservoirs underpin efforts to reduce risks to human health and enhance bat conservation, but are notoriously challenging to resolve. For vampire bat rabies, the geographical scale of enzootic cycles, whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583e4a9922af68042e408c83b3ca5150
https://eprints.gla.ac.uk/277082/1/277082.pdf
https://eprints.gla.ac.uk/277082/1/277082.pdf
Autor:
Sarah Guth, Nardus Mollentze, Katia Renault, Daniel G. Streicker, Elisa Visher, Mike Boots, Cara E. Brook
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(14)
Significance The clear need to mitigate zoonotic risk has fueled increased viral discovery in specific reservoir host taxa. We show that a combination of viral and reservoir traits can predict zoonotic virus virulence and transmissibility in humans,
Autor:
Rory Gibb, Gregory F. Albery, Nardus Mollentze, Evan A. Eskew, Liam Brierley, Sadie J. Ryan, Stephanie N. Seifert, Colin J. Carlson
Publikováno v:
Biology Letters
Host-virus association data underpin research into the distribution and eco-evolutionary correlates of viral diversity and zoonotic risk across host species. However, current knowledge of the wildlife virome is inherently constrained by historical di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8802c9784b0f0a12e67ed9955ade5c
https://eprints.gla.ac.uk/262031/1/262031.pdf
https://eprints.gla.ac.uk/262031/1/262031.pdf