Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Narcyz Knap"'
Autor:
Claudia Musial, Narcyz Knap, Renata Zaucha, Paulina Bastian, Giampaolo Barone, Giosuè Lo Bosco, Fabrizio Lo-Celso, Lucyna Konieczna, Mariusz Belka, Tomasz Bączek, Antonella Marino Gammazza, Alicja Kuban-Jankowska, Francesco Cappello, Stephan Nussberger, Magdalena Gorska-Ponikowska
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102395- (2022)
Lung cancer is one of the most common cancers worldwide, causing nearly one million deaths each year. Herein, we present the effect of 2-methoxyestradiol (2-ME), the endogenous metabolite of 17β-estradiol (E2), on non-small cell lung cancer (NSCLC)
Externí odkaz:
https://doaj.org/article/499a3a75f7f3413b953812e55fd813a7
Autor:
Magdalena Gorska-Ponikowska, Agata Ploska, Dagmara Jacewicz, Michal Szkatula, Giampaolo Barone, Giosuè Lo Bosco, Fabrizio Lo Celso, Aleksandra M Dabrowska, Alicja Kuban-Jankowska, Monika Gorzynik-Debicka, Narcyz Knap, Lech Chmurzynski, Lawrence Wawrzyniec Dobrucki, Leszek Kalinowski, Michal Wozniak
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
2-methoxyestradiol (2-ME) is a physiological anticancer compound, metabolite of 17β-estradiol. Previously, our group evidenced that from mechanistic point of view one of anticancer mechanisms of action of 2-ME is specific induction and nuclear hijac
Externí odkaz:
https://doaj.org/article/dde580077c8249e19636bedf5e9a7eea
Autor:
Malgorzata Halon‐Golabek, Andzelika Borkowska, Jan J. Kaczor, Wieslaw Ziolkowski, Damian J. Flis, Narcyz Knap, Kajetan Kasperuk, Jedrzej Antosiewicz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 3, Pp 557-569 (2018)
Abstract Background Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not b
Externí odkaz:
https://doaj.org/article/bfa4cc2778d143ea9e8da409b832f588
Autor:
Dagmara Jacewicz, Aleksandra Dabrowska, Dariusz Wyrzykowski, Joanna Pranczk, Michal Wozniak, Jolanta Kubasik-Juraniec, Narcyz Knap, Kamila Siedlecka, Alexander J. Neuwelt, Lech Chmurzynski
Publikováno v:
Sensors, Vol 10, Iss 1, Pp 280-291 (2009)
The direct and accurate estimation of nitric dioxide levels is an extremely laborious and technically demanding procedure in the molecular diagnostics of inflammatory processes. The aim of this work is to demonstrate that a stop-flow technique utiliz
Externí odkaz:
https://doaj.org/article/59f0dba8a5dc45da8684037903ea8d59
Autor:
Alexander J. Neuwelt, Y. Jeffrey Wu, Narcyz Knap, Marcin Losin, Edward A. Neuwelt, Michael A. Pagel, Steven Warmann, Joerg Fuchs, Piotr Czauderna, Michal Wozniak
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 10, Pp 1003-1011 (2009)
Background/Aims: Acetaminophen overdose causes hepatotoxicity mediated by toxic metabolites generated through the cytochrome P450 enzyme. The objective of this study was to investigate whether acetaminophen (AAP) can enhance cisplatin (CDDP) cytotoxi
Externí odkaz:
https://doaj.org/article/e7d837ca44f141b6be0fe106e8127282
Autor:
Magdalena Gorska, Antonella Marino Gammazza, Michal Aleksander Zmijewski, Claudia Campanella, Francesco Cappello, Tomasz Wasiewicz, Alicja Kuban-Jankowska, Agnieszka Daca, Alicja Sielicka, Urszula Popowska, Narcyz Knap, Jakub Antoniewicz, Takashi Wakabayashi, Michal Wozniak
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71135 (2013)
Osteosarcoma is one of the most malignant tumors of childhood and adolescence that is often resistant to standard chemo- and radio-therapy. Geldanamycin and geldanamycin analogs have been recently studied as potential anticancer agents for osteosarco
Externí odkaz:
https://doaj.org/article/f82aff0e2b464c539e76049802cccbb9
Autor:
Alicja Kuban-Jankowska, Jack A Tuszynski, Philip Winter, Magdalena Gorska, Narcyz Knap, Michal Wozniak
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52495 (2012)
Hydrogen peroxide induces oxidation and consequently inactivation of many protein tyrosine phosphatases. It was found that hydrogen peroxide, in the presence of carboxylic acids, was efficiently activated to form even more potent oxidant - peroxy aci
Externí odkaz:
https://doaj.org/article/adf6ddcd969d42ac88d4b352b029f390
Autor:
Jedrzej Antosiewicz, Agata Wronska, Andzelika Borkowska, Katarzyna Kaczor, Narcyz Knap, Anna Herman-Antosiewicz, Wieslaw Ziolkowski
Publikováno v:
European Journal of Nutrition
Purpose Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases and also promotes neuronal death in various neurodegenerative diseases. There is evidence that iron can mediate homocysteine (Hcy) toxicity. Thus, the aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780e8025565a529f498a1f61a8d517da
http://europepmc.org/articles/PMC7987610
http://europepmc.org/articles/PMC7987610
Autor:
Lech Chmurzyński, Giampaolo Barone, Agata Płoska, Aleksandra Dabrowska, Michal Szkatula, Alicja Kuban-Jankowska, Dagmara Jacewicz, Fabrizio Lo Celso, Narcyz Knap, Michal Wozniak, Magdalena Gorska-Ponikowska, Lawrence W. Dobrucki, Giosuè Lo Bosco, Monika Gorzynik-Debicka, Leszek Kalinowski
Publikováno v:
Redox Biology, Vol 32, Iss, Pp-(2020)
Redox Biology
Redox Biology
2-methoxyestradiol (2-ME) is a physiological anticancer compound, metabolite of 17β-estradiol. Previously, our group evidenced that from mechanistic point of view one of anticancer mechanisms of action of 2-ME is specific induction and nuclear hijac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0452055dfbf00ffda95246a17f21cdbf
http://www.sciencedirect.com/science/article/pii/S2213231720302366
http://www.sciencedirect.com/science/article/pii/S2213231720302366
Autor:
Jedrzej Antosiewicz, Kajetan Kasperuk, Jan J. Kaczor, Andzelika Borkowska, Narcyz Knap, Damian Jozef Flis, Malgorzata Halon-Golabek, Wieslaw Ziolkowski
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 9:557-569
Background Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not been studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd3964a876a2bb2dbbe4ec9d87cfa4bc
https://doi.org/10.1002/jcsm.12283
https://doi.org/10.1002/jcsm.12283