Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Narciso Olvera"'
Autor:
Benjamin Margolis, Fanny Dao, Michael Licciardi, Selim Misirlioglu, Narciso Olvera, Sitharam Ramaswami, Douglas A. Levine
Publikováno v:
Gynecologic Oncology Reports, Vol 37, Iss , Pp 100850- (2021)
Objective: We sought to characterize the variability of CCNE1 amplification among metastatic sites of CCNE1 amplified high grade serous carcinoma (HGSC) cases to investigate the feasibility of targeting this alteration for therapeutic purposes. Metho
Externí odkaz:
https://doaj.org/article/253cd004ef4a448a9d04ad11dff63453
Autor:
Jennifer Ducie, Fanny Dao, Michael Considine, Narciso Olvera, Patricia A. Shaw, Robert J. Kurman, Ie-Ming Shih, Robert A. Soslow, Leslie Cope, Douglas A. Levine
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profi
Externí odkaz:
https://doaj.org/article/5da5d07cf2c84f32a259855428b75840
Autor:
Jill H. Tseng, Maria Bisogna, Lien N. Hoang, Narciso Olvera, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Anil K. Sood, Douglas A. Levine, Petar Jelinic
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Uterine carcinosarcomas (UCSs) are highly aggressive malignancies associated with poor prognoses and limited treatment options. These tumors are hypothesized to develop from the endometrial adenocarcinoma (EAC) through epithelial-mesenchymal
Externí odkaz:
https://doaj.org/article/39afe2c454444995b3b4910c761be8ac
Autor:
Joyce N. Barlin, Qin C. Zhou, Mario M. Leitao, Maria Bisogna, Narciso Olvera, Karin K. Shih, Anders Jacobsen, Nikolaus Schultz, William D. Tap, Martee L. Hensley, Gary K. Schwartz, Jeff Boyd, Li-Xuan Qin, Douglas A. Levine
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 2, Pp 183-189 (2015)
The molecular etiology of uterine leiomyosarcoma (ULMS) is poorly understood, which accounts for the wide disparity in outcomes among women with this disease. We examined and compared the molecular profiles of ULMS and normal myometrium (NL) to ident
Externí odkaz:
https://doaj.org/article/374091b1a94448208ed2e446f68586cf
Publikováno v:
BioTechniques, Vol 43, Iss 1, Pp 41-48 (2007)
Externí odkaz:
https://doaj.org/article/c391f788e29f446dad9f5f4c8053cf57
Autor:
Bhavana Pothuri, Mario M Leitao, Douglas A Levine, Agnès Viale, Adam B Olshen, Crispinita Arroyo, Faina Bogomolniy, Narciso Olvera, Oscar Lin, Robert A Soslow, Mark E Robson, Kenneth Offit, Richard R Barakat, Jeff Boyd
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10358 (2010)
BackgroundThe high mortality rate associated with epithelial ovarian carcinoma (EOC) reflects diagnosis commonly at an advanced stage, but improved early detection is hindered by uncertainty as to the histologic origin and early natural history of th
Externí odkaz:
https://doaj.org/article/0a051a1d3a2641e4a0d8b50c277be9a9
Autor:
Amnon A, Berger, Emily A, Kawaler, Fanny, Dao, Selim, Misirlioglu, Ernesto Arostegui, Fernandez, Narciso, Olvera, Elke, Van Oudenhove, Deborah, DeLair, Douglas A, Levine
Publikováno v:
Gynecologic Oncology. 167:323-333
Treatment options and associated biomarkers for advanced and recurrent disease are limited. Endometrial cancers (ECs) with CTNNB1 exon 3 mutations appear to have preferential response to bevacizumab, an anti-angiogenesis treatment, though the mechani
Autor:
David B. Solit, Douglas A. Levine, Neal Rosen, Chris Sander, Barry S. Taylor, Adriana Heguy, David R. Spriggs, Elisa de Stanchina, Tari A. King, Carol Aghajanian, Qing-Bai She, Ellen V. Stevens, Narciso Olvera, Manickam Janikariman, Stefano Scarperi, Dilip D. Giri, Rita A. Sakr, Maggie L. Westfal, Nikolaus Schultz, Aphrothiti J. Hanrahan
PDF file - 356K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1386149fd58db0ee79952590e836216f
https://doi.org/10.1158/2159-8290.22529192
https://doi.org/10.1158/2159-8290.22529192
Autor:
Benjamin G. Neel, Robert A. Weinberg, Douglas A. Levine, Fanny Dao, Narciso Olvera, Cynthia A. Loomis, Connor J.R. Foster, Wei Wei, Shengqing Gu, Igor Dolgalev, Hao Ran, Sonia Iyer, Shuang Zhang
Supplementary data includes suppl methods, FigS1-8, Table S1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e556f12c5f6a29171d95995c5f98c40
https://doi.org/10.1158/2159-8290.22536016.v1
https://doi.org/10.1158/2159-8290.22536016.v1
Autor:
Douglas A. Levine, Colin B. Begg, Jaya M. Satagopan, Magali Cavatore, Narciso Olvera, Liliana Villafania, Faina Bogomolniy, Qin Zhou, Li-Xuan Qin
Randomization and blocking have the potential to prevent the negative impacts of nonbiologic effects on molecular biomarker discovery. Their use in practice, however, has been scarce. To demonstrate the logistic feasibility and scientific benefits of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114c053033ef91c8e09e8ee8f29f8381
https://doi.org/10.1158/1078-0432.c.6522912
https://doi.org/10.1158/1078-0432.c.6522912