Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Narayanaperumal Pravin"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6085 (2022)
Alzheimer’s disease (AD) is multifactorial, progressive and the most predominant cause of cognitive impairment and dementia worldwide. The current “one-drug, one-target” approach provides only symptomatic relief to the condition but is unable t
Externí odkaz:
https://doaj.org/article/e42477cc6cc8458aa6f6f67dc8cdb3d7
Autor:
Rakesh Kumar, Namrata Singh, Per Nilsson, Samir K. Maji, Ambuja Navalkar, Pardeep Kumar, Ganesh M. Mohite, Ashutosh Kumar, Maheswaran Shanmugam, Makoto Shimozawa, Rajlaxmi Panigrahi, Shalini Tripathi, Shaffi Manchanda, Jan Johansson, Laxmikant G. Gadhe, Narayanaperumal Pravin
Publikováno v:
Journal of Neurochemistry. 156:1003-1019
Protein aggregation into amyloid fibrils is a key feature of a multitude of neurodegenerative diseases such as Alzheimer's, Parkinson's, and Prion disease. To detect amyloid fibrils, fluorophores with high sensitivity and better efficiency coupled wi
Autor:
Nattamai Bhuvanesh, Vijayan Viswanathan, Narayanaperumal Pravin, Raju Senthil Kumar, Dharmasivam Mahendiran, Aziz Kalilur Rahiman, Devadasan Velmurugan
Publikováno v:
ChemistrySelect. 3:7100-7111
A series of six new bis(thiosemicarbazone)copper(I) complexes of the type [Cu(L1–6)2Cl] (1−6) were synthesized and characterized. The complexes adopted trigonal planar ′Y′ shaped geometry coordinating through two thione sulphur atoms of two l
Autor:
Narayanaperumal Pravin, Natarajan Raman, Ponnukalai Ponya Utthra, Vellaichamy Muniyandi, Ganesan Kumaravel
Publikováno v:
Energy and Environment Focus. 6:184-192
Publikováno v:
Journal of Molecular Structure. 1123:162-170
Eight transition metal complexes were designed to achieve maximum biological efficacy. They were characterized by elemental analysis and various other spectroscopic techniques. The monomeric complexes were found to espouse octahedral geometry and non
Autor:
Dharmasivam Mahendiran, Balasubramanian Rajkapoor, Narayanaperumal Pravin, Sekar Vinoth Kumar, Raju Senthil Kumar
Publikováno v:
Journal of Applied Pharmaceutical Science. :199-209
Indigofera linnaei Ali., has been widely used in folk medicine to treat inflammation, liver disorders and swelling of stomach. Earlier studies showed that methanolic extract of Indigofera linnaei (MEIL) possess antioxidant, free radical scavenging, a
Publikováno v:
International Journal of Biological Macromolecules. 79:837-855
The serendipitous discovery of the anticancer drug cisplatin cemented medicinal inorganic chemistry as an independent discipline in 1960s. DNA and protein kinases are one of the major intracellular targets of many anticancer drugs. It is thus highly
Publikováno v:
Journal of Molecular Structure. 1086:56-63
A new tridentate ligand, (E)-(2-((2-hydroxybenzylidene)amino)phenyl)(phenyl)methanone and its four metal(II) chelates have been designed and synthesized. They were structurally characterized by elemental analysis, FT IR, UV–vis, 1H NMR, 13C NMR, ma
Publikováno v:
Journal of Molecular Structure. 1081:477-485
Four new metallonucleases of the composition [MLCl] (where M = Cu(II), Ni(II), Zn(II) and Co(II); L = Knoevenagel condensate Schiff base, obtained by the condensation reaction of 1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione with p- nit
Impact of metallonucleases on DNA interactions: Structural validation and in-vitro antibiogram assay
Publikováno v:
Inorganic Chemistry Communications. 46:60-64
Four novel complexes were synthesized using 2-aminobenzophenone Schiff base precursor and characterized by various analytical techniques. FT-IR results demonstrate that the Schiff base ligand, obtained by the condensation of 2-aminobenzophenone with