Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Narayanan K. Narayanan"'
Autor:
Muhammed Majeed, Narayanan K. Narayanan, Lakshmi Mundkur, Priji Prakasan, Kalyanam Nagabhushanam
Publikováno v:
Nutraceuticals, Vol 3, Iss 3, Pp 329-352 (2023)
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease showing an exponential increase in its prevalence all over the world. High blood glucose level is one of the main clinical signs of the disease. Although several classes of drugs are avai
Externí odkaz:
https://doaj.org/article/ecf6551af5ca4cd6adee7620ad98135d
Publikováno v:
Phytotherapy Research
A double‐blind, placebo‐controlled human trial was conducted to evaluate the safety and efficacy of a standardized oral supplementation of Boswellin®, a novel extract of Boswellia serrata extract (BSE) containing 3‐acetyl‐11‐keto‐β‐bo
Autor:
Hideki Mori, George Miller, Kazuhiro Kunimasa, Bhagavathi A. Narayanan, Upender Manne, Mari Mori, Kazuki Nakamura, Amit K. Tiwari, Narayanan K. Narayanan, Yukio Yamori
Publikováno v:
Cancer Medicine
Melinjo (Gnetum gnemon L.) seed extract (MSE) and its active ingredient gnetin C (GC), a resveratrol dimer, have been shown to possess a broad spectrum of pharmacological activities. In this study, we investigated the antitumor activity of MSE and GC
Autor:
Bhagavathi A. Narayanan, Amit K. Tiwari, Jesika S. Faridi, Ritu Malla, Narayanan K. Narayanan, Charles R. Ashby
Publikováno v:
Biochemical and Biophysical Research Communications. 463:161-166
Dysregulation of PI3K-AKT-mTOR pathway has been reported in various pathologies, such as cancer and insulin resistance. The proline-rich AKT substrate of 40-kDa (PRAS40), also known as AKT substrate 1 (AKT1S1), lies at the crossroads of these cascade
Publikováno v:
International Journal of Cancer. 125:1-8
Increasing interest in the use of phytochemicals to reduce prostate cancer led us to investigate 2 potential agents, curcumin and resveratrol as preventive agents. However, there is concern about the bioavailability of these agents pertinent to the p
Autor:
Bhagavathi A. Narayanan, Narayanan K. Narayanan, Maarten C. Bosland, Bandaru S. Reddy, Dominick Nargi, Lori Horton
Publikováno v:
The Prostate. 69:133-141
BACKGROUND Prostate tissue microenvironment is susceptible to several risk factors including carcinogens, dietary factors, hormones, cytokines and growth factors that could induce chronic inflammation. Because of the difference in the serum levels an
Publikováno v:
Journal of Postgenomics Drug & Biomarker Development.
Autor:
Piyush Trivedi, Narayanan K. Narayanan, Esther A. Suswam, Crystal Lee, Satyanarayana R. Pondugula, Joshua Moore, Kodye L. Abbott, Chandrabose Karthikeyan, Roopali Mittal, Amit K. Tiwari, Upender Manne
Publikováno v:
Bioorganicmedicinal chemistry. 23(3)
Naturally occurring condensed quinolines have anticancer properties. In efforts to find active analogues, we designed and synthesized eight polycyclic heterocycles with a pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinoline framework (IND series). The com
Autor:
Bhagavathi A. Narayanan, Narayanan K. Narayanan, Dhimant Desai, Bandaru S. Reddy, Brian Pittman
Publikováno v:
Carcinogenesis. 25:2443-2449
Epidemiological and preclinical studies suggest that diets that are rich in n-3 polyunsaturated fatty acids (PUFAs) and selenium (Se) reduce the risk of colon cancer. Studies conducted in our laboratory have indicated that synthetic organoselenium 1,
Publikováno v:
Clinical Cancer Research. 10:7727-7737
Purpose: Epidemiologic studies have revealed a decreased risk of colon cancer among people who have regularly taken cyclooxygenase (COX)-2 inhibitors such as aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Whereas the selective COX-2