Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Narayan Prasad, Parajuli"'
Autor:
Narayan Prasad Parajuli, Andrew Emmerich, Chandra Sekhar Mandava, Michael Y. Pavlov, Suparna Sanyal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Thermorubin is a ribosome-targeting antibiotic. Here, using fast-kinetics and cryoEM, the authors reveal that thermorubin primarily blocks ribosome-recycling by tethering the ribosomal subunits besides impeding translation elongation and termination
Externí odkaz:
https://doaj.org/article/2e861c4a662d405581bb5cc5e7be1422
Autor:
Roshan Pandit, Balkrishna Awal, Sumesh Shreekhanda Shrestha, Govardhan Joshi, Basista Prasad Rijal, Narayan Prasad Parajuli
Publikováno v:
Interdisciplinary Perspectives on Infectious Diseases, Vol 2020 (2020)
Urinary tract infections (UTI) represent the most common bacterial infections among patients visiting outpatient clinics of healthcare centers in Nepal. However, treatment of such infections is compounded by emergence and spread of multidrug-resistan
Externí odkaz:
https://doaj.org/article/9d7a86c2df1942a5a03b93a6f2cad397
Autor:
Narayan Prasad Parajuli, Subhash Prasad Acharya, Shyam Kumar Mishra, Keshab Parajuli, Basista Prasad Rijal, Bharat Mani Pokhrel
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 6, Iss 1, Pp 1-9 (2017)
Abstract Background Healthcare associated infections (HCAI) and antimicrobial resistance are principal threats to the patients of intensive care units and are the major determining factors for patient outcome. They are associated with increased morbi
Externí odkaz:
https://doaj.org/article/a3d5b176891448c3af03353b9ccbccf1
Autor:
Narayan Prasad Parajuli, Pooja Maharjan, Hridaya Parajuli, Govardhan Joshi, Deliya Paudel, Sujan Sayami, Puspa Raj Khanal
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 6, Iss 1, Pp 1-7 (2017)
Abstract Background Emergence of Extended-spectrum beta-lactamase producing Escherichia coli causing urinary tract infections (UTI) among pediatric patients is an increasing problem worldwide. However, very little is known about pediatric urinary tra
Externí odkaz:
https://doaj.org/article/1d28e1d1c5544d3d9e30f87c6decb1cf
Publikováno v:
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2017 (2017)
Bloodstream infections (BSIs) are among the significant causes of morbidity and mortality for patients of all age groups. However, very little is known about the trends of bacterial bloodstream infections and antimicrobial susceptibilities among pedi
Externí odkaz:
https://doaj.org/article/53ea9648f8eb48ad8e58513ee8be3b0c
Publikováno v:
International Journal of Microbiology, Vol 2017 (2017)
Enteric fever continues to be an important public health problem especially in developing countries of the tropical region including Nepal. In this study, we aimed to investigate the incidence of enteric fever associated with Salmonella enterica and
Externí odkaz:
https://doaj.org/article/f57eeecfe5ae4f60b0e6d8a86072d58f
Autor:
Narayan Prasad Parajuli, Govardhan Joshi, Bashu Dev Pardhe, Jyotsna Shakya, Anjeela Bhetwal, Shreena Shakya, Roshan Pandit, Sumesh Shreekhanda Shrestha, Puspa Raj Khanal
Publikováno v:
Case Reports in Infectious Diseases, Vol 2017 (2017)
Shigellosis is an acute infectious disease characterized as severe bloody diarrhea (dysentery) and is accountable for a significant burden of morbidity and mortality especially in children under the age of 5 years. Antimicrobial therapy is required i
Externí odkaz:
https://doaj.org/article/11f651649e9a4f43bc16bdd78156dcca
Publikováno v:
Journal of Pathogens, Vol 2017 (2017)
Pyogenic wound infections are one of the most common clinical entities caused and aggravated by the invasion of pathogenic organisms. Prompt and aggressive antimicrobial therapy is needed to reduce the burden and complications associated with these i
Externí odkaz:
https://doaj.org/article/8b1b2ba67c6e4baf87837e223c4ac88b
Autor:
Bashu Dev Pardhe, Sumitra Ghimire, Jyotsna Shakya, Sabala Pathak, Shreena Shakya, Anjeela Bhetwal, Puspa Raj Khanal, Narayan Prasad Parajuli
Publikováno v:
Biochemistry Research International, Vol 2017 (2017)
Cardiovascular disease (CVD) is one of the leading causes of death worldwide which is more prevalent in women after menopause. Hormonal changes associated with menopause are accountable for dyslipidemic pattern that causes CVD and associated complica
Externí odkaz:
https://doaj.org/article/f61734a39665403ebf27f512b4469709
Autor:
Arindam, De Tarafder, Narayan Prasad, Parajuli, Soneya, Majumdar, Betül, Kaçar, Suparna, Sanyal
Publikováno v:
Molecular Biology and Evolution
It has been hypothesized that early enzymes are more promiscuous than their extant orthologs. Whether or not this hypothesis applies to the translation machinery, the oldest molecular machine of life, is not known. Efficient protein synthesis relies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6608b54b26607c227bed6e37d31fe80
https://pubmed.ncbi.nlm.nih.gov/33871630
https://pubmed.ncbi.nlm.nih.gov/33871630