Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Narayan P. S. Cheruvu"'
Autor:
Aniruddha C. Amrite, Pi-Wan Cheng, Rajagopal N. Aravalli, Uday B. Kompella, Sneha Sundaram, Narayan P. S. Cheruvu
Publikováno v:
Clinical Research and Regulatory Affairs. 21:1-28
Lung gene therapy is a promising therapeutic approach for several difficult to treat disorders such as cystic fibrosis, α1‐antitrypsin deficiency, and cancers. Although several gene therapy protocols have proven success in preclinical studies, whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfe14c8125b8dc4ca4dee6dba070e95
https://doi.org/10.1081/crp-120039559
https://doi.org/10.1081/crp-120039559
Publikováno v:
AAPS Advances in the Pharmaceutical Sciences Series ISBN: 9781461482468
Pharmaco-Imaging in Drug and Biologics Development
Pharmaco-Imaging in Drug and Biologics Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b1687a9a3dde5d83077d72d000b809a
https://doi.org/10.1007/978-1-4614-8247-5
https://doi.org/10.1007/978-1-4614-8247-5
Publikováno v:
Pharmaco-Imaging in Drug and Biologics Development ISBN: 9781461482468
Today’s revolution in imaging technologies in the biomedical sciences has raised much needed hope for improved diagnostics, therapeutics, and the eventual cure of many debilitating illnesses. Imaging itself has become the seed technology that has f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::536234dfa9c75cde73b491a47eba4c56
https://doi.org/10.1007/978-1-4614-8247-5_13
https://doi.org/10.1007/978-1-4614-8247-5_13
Transscleral retinal delivery of celecoxib, an anti-inflammatory and anti-VEGF agent, is restricted by its poor solubility and binding to the melanin pigment in choroid-RPE. The purpose of this study was to develop soluble prodrugs of celecoxib with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec0b00c2974c50c947740724f3f0f6d
https://europepmc.org/articles/PMC3311925/
https://europepmc.org/articles/PMC3311925/
Age-related macular degeneration (AMD) and diabetic retinopathy (DR) are two major causes of blindness. In these disorders, growth factors such as vascular endothelial growth factor (VEGF) are upregulated, leading to either enhanced vascular permeabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf841542f49b076388b48def64835f3
https://europepmc.org/articles/PMC2858240/
https://europepmc.org/articles/PMC2858240/
Autor:
Ashim K. Mitra, Viral Kansara, Paul Missel, Narayan P. S. Cheruvu, Sridhar Duvvuri, Aniruddha C. Amrite, Uday B. Kompella, James E. Chastain
The purpose of this study was to evaluate partitioning into and transport across posterior segment tissues (sclera, retinal pigment epithelium (RPE)-choroid) of AL-4940, the active metabolite of angiostatic cortisene anecortave acetate (AL-3789).Tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd760b3821e4ea334bdd81040549270
https://europepmc.org/articles/PMC3158576/
https://europepmc.org/articles/PMC3158576/
Publikováno v:
Pharmaceutical research. 26(2)
To investigate the effects of diabetes on transscleral retinal delivery of celecoxib in albino and pigmented rats.Albino (Sprague Dawley-SD) and pigmented (Brown Norway-BN) rats were made diabetic by a single intraperitoneal injection of streptozotoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20628a70558d44e2ac6ac6aadfa219c
https://pubmed.ncbi.nlm.nih.gov/18987961
https://pubmed.ncbi.nlm.nih.gov/18987961
Publikováno v:
Molecular Pharmaceutics. 12:2558-2558
Transscleral retinal delivery of celecoxib, an anti-inflammatory and anti-VEGF agent, is restricted by its poor solubility and binding to the melanin pigment in choroid-RPE. The purpose of this study was to develop soluble prodrugs of celecoxib with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef9186977a7d9b1f5f2ef3e36ee798f
https://doi.org/10.1021/acs.molpharmaceut.5b00366
https://doi.org/10.1021/acs.molpharmaceut.5b00366
Celecoxib, a potent cyclooxygenase (COX)-2 inhibitor is currently being used as an anti-inflammatory agent for the treatment of rheumatoid arthritis and osteoarthritis. It also is under investigation for the treatment of various malignant and premali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24d5053a0660d6314ca0be1f58c8d15
https://europepmc.org/articles/PMC3324981/
https://europepmc.org/articles/PMC3324981/
Publikováno v:
Pharmaceutical research. 21(7)
To compare the systemic delivery of deslorelin following intratracheal administration of different deslorelin formulations. The formulations included dry powders of deslorelin, large-porous deslorelin-poly(lactide-co-glycolide) (PLGA) particles, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357a15a5c807aa6e6a42efe915337118
https://pubmed.ncbi.nlm.nih.gov/15290850
https://pubmed.ncbi.nlm.nih.gov/15290850