Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Narat J. Eungdamrong"'
Autor:
Narat J. Eungdamrong, Zongyou Guo, Angela M. Christiano, Claire A. Higgins, Wenhan Lee, Brian M. Gillette, Samuel K. Sia
Publikováno v:
Experimental Biology and Medicine. 239:1215-1224
The tremendous cost of drug development is often attributed to the long time interval between identifying lead compounds in preclinical studies to assessing clinical efficacy in randomized clinical trials. Many candidate molecules show promise in cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3d5a8e1425e75a3bc5a8dad88c0a0f
https://doi.org/10.1177/1535370214538747
https://doi.org/10.1177/1535370214538747
Autor:
Anthony Hasseldine, Prahlad T. Ram, Avi Ma'ayan, J. Jeremy Rice, Robert D. Blitzer, Narat J. Eungdamrong, Elizabeth A. Grace, Benjamin J. Dubin-Thaler, Susana R. Neves, Ravi Iyengar, Gustavo Stolovitzky, Aaron Kershenbaum, Sherry L. Jenkins, Gehzi Weng
Publikováno v:
Science. 309:1078-1083
We developed a model of 545 components (nodes) and 1259 interactions representing signaling pathways and cellular machines in the hippocampal CA1 neuron. Using graph theory methods, we analyzed ligand-induced signal flow through the system. Specifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d212d14fd202af532684c60dd886bd67
https://doi.org/10.1126/science.1108876
https://doi.org/10.1126/science.1108876
Autor:
Lakshmi A. Devi, Tracy Nguyen, Narat J. Eungdamrong, Ivone Gomes, J. Dedrick Jordan, Wasif Ali, John Cijiang He, Trever G. Bivona, Ravi Iyengar, Mark R. Philips
Publikováno v:
Journal of Biological Chemistry. 280:11413-11421
The G(alpha)o/i-coupled CB1 cannabionoid receptor induces neurite outgrowth in Neuro-2A cells. The mechanisms of signaling through G(alpha)o/i to induce neurite outgrowth were studied. The expression of G(alpha)o/i reduces the stability of its direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a74f3093292a4cb53f251cdab92da7d
https://doi.org/10.1074/jbc.m411521200
https://doi.org/10.1074/jbc.m411521200
Autor:
Narat J. Eungdamrong, Ravi Iyengar
Publikováno v:
Trends in Cell Biology. 14:661-669
Cellular components interact with each other to form networks that process information and evoke biological responses. A deep understanding of the behavior of these networks requires the development and analysis of mathematical models. In this articl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a8f56e282331fb1c4f39c662f2e30d
https://doi.org/10.1016/j.tcb.2004.10.007
https://doi.org/10.1016/j.tcb.2004.10.007
Autor:
Narat J. Eungdamrong, Ravi Iyengar
Publikováno v:
Bioinformatics-From Genomes to Therapies
Cell signaling pathways interact with one another to form networks in mammalian systems. Such networks are complex in their organization and exhibit emergent properties such as bistability and ultrasensitivity. Analysis of signaling networks requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554b081067afda66d2f0795cc7149587
https://doi.org/10.1016/j.biolcel.2004.03.004
https://doi.org/10.1016/j.biolcel.2004.03.004
Autor:
James L. McGrath, Charles I. Fisher, Scot C. Kuo, Lakshminarayanan Mahadevan, Fay Peng, Timothy J. Mitchison, Narat J. Eungdamrong
Publikováno v:
Current Biology. 13(4):329-332
The intracellular movement of the bacterial pathogen Listeria monocytogenes has helped identify key molecular constituents of actin-based motility (recent reviews [1–4]). However, biophysical as well as biochemical data are required to understand h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4da23adec3f13245539691d14ed4b4
Autor:
Ronald E. Gordon, Hong Li, Avi Ma'ayan, Gomathi Jayaraman, Simon Hardy, John Cijiang He, Narat J. Eungdamrong, Peter Y. Chuang, Huabao Xiong, Yibang Chen, Ravi Iyengar, Wei Fang, Mohit Jain, Evren U. Azeloglu, Susana R. Neves
Publikováno v:
Science Signaling. 7
Podocytes are kidney cells with specialized morphology that is required for glomerular filtration. Diseases, such as diabetes, or drug exposure that causes disruption of the podocyte foot process morphology results in kidney pathophysiology. Proteomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631e6e82f45dc9f05a86b3e2d3680274
https://doi.org/10.1126/scisignal.2004621
https://doi.org/10.1126/scisignal.2004621
Autor:
Narat J. Eungdamrong, Ravi Iyengar
Publikováno v:
Biophysical Journal. (3):808-815
Imaging experiments have shown that cell signaling components such as Ras can be activated by growth factors at distinct subcellular locations. Trafficking between these subcellular locations is a regulated dynamic process. The effects of trafficking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466c0b9f4533a329cd0cd7456eae28cf
Autor:
Gibran Shaikh, Andrew G. Franks, Renee Fruchter, Narat J. Eungdamrong, Kathryn L. Myers, Hyun Soo Lee
Publikováno v:
JAAD Case Reports
Bullous lupus erythematosus is an autoantibody-mediated subepidermal blistering disease that occurs in patients with systemic lupus erythematosus (SLE).1 Erythema gyratum repens (EGR) is a clinical diagnosis characterized by a wood grain pattern of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be44f6355e997ea7256f0c6b8c1dae8