Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Narasimhan J. Venkatachari"'
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7470 (2009)
Dendritic cells (DC) play a pivotal role in transmission and dissemination of HIV-1. Earlier studies reported that DC present at the site of infection trap virus particles via DC-SIGN and transfer the virus to the interacting naïve T cells. This pro
Externí odkaz:
https://doaj.org/article/f5334681bcaf4a99a3ed0457b7b1964a
Autor:
Charles R. Rinaldo, Ziv Bar-Joseph, Siddhartha Jain, Ansuman Chattopadhyay, Leah A Walker, James T. Becker, Ned Sacktor, Velpandi Ayyavoo, Andrew J. Levine, Shalmali Bivalkar-Mehla, Narasimhan J. Venkatachari, Ann B. Ragin, Eric C. Seaberg, Eileen M. Martin
Publikováno v:
AIDS. 31:623-633
OBJECTIVE HIV-1 viral proteins and host inflammatory factors have a direct role in neuronal toxicity in vitro; however, the contribution of these factors in vivo in HIV-1-associated neurocognitive disorder (HAND) is not fully understood. We applied n
Autor:
Phalguni Gupta, Narasimhan J. Venkatachari, Feng Han, Nicholas S. Giacobbi, Nicolas Sluis-Cremer, Benni Vargas, Anwesha Sanyal
Signaling pathways play a key role in HIV-1 latency. In this study, we used the 24ST1NLESG cell line of HIV-1 latency to screen a library of structurally diverse, medicinally active, cell permeable kinase inhibitors, which target a wide range of sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92ee024163fe8dfacd0eb4883784919
https://europepmc.org/articles/PMC6355603/
https://europepmc.org/articles/PMC6355603/
Autor:
Narasimhan J. Venkatachari, Ziv Bar-Joseph, Siddhartha Jain, Velpandi Ayyavoo, Joel P. Arrais
Publikováno v:
Bioinformatics
Motivation: Most methods for reconstructing response networks from high throughput data generate static models which cannot distinguish between early and late response stages. Results: We present TimePath, a new method that integrates time series and
Autor:
Ming Ding, Jennifer M. Zerbato, Bruce K. Patterson, Nicolas Sluis-Cremer, Phalguni Gupta, Anwesha Sanyal, Amanda Chargin, Narasimhan J. Venkatachari, Nicholas S. Giacobbi, Deena Ratner, Yue Chen, Charles R. Rinaldo, Robbie B. Mailliard
Publikováno v:
Nature medicine
Although antiretroviral therapy can suppress HIV-1 infection to undetectable levels of plasma viremia, integrated latent HIV-1 genomes that encode replication competent virus persist in resting CD4+ T cells. This latent HIV-1 reservoir represents a m
Autor:
Vinay K. Pathak, Chawaree Chaipan, Wei-Shau Hu, Narasimhan J. Venkatachari, Kari A. Dilley, Tobias Paprotka, Krista A. Delviks-Frankenberry
Publikováno v:
Journal of Virology. 85:4888-4897
Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus recently isolated from human prostate cancer and peripheral blood mononuclear cells (PBMCs) of patients with chronic fatigue syndrome (CFS). We and others have shown that host
Autor:
Narasimhan J. Venkatachari, Jianbo Chen, Yeshitila N Friew, Chawaree Chaipan, Vinay K. Pathak, Krista A. Delviks-Frankenberry, Jessica L. Smith, Ryan C. Burdick, Wei-Shau Hu
Publikováno v:
Journal of Virology. 84:10241-10253
Recent studies have shown that APOBEC3G (A3G), a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, is localized to cytoplasmic mRNA-processing bodies (P bodies). However, the functional relevance of A3G colocalization with
Inhibition of Xenotropic Murine Leukemia Virus-Related Virus by APOBEC3 Proteins and Antiviral Drugs
Autor:
Chawaree Chaipan, Tobias Paprotka, Narasimhan J. Venkatachari, Vinay K. Pathak, Ryan C. Burdick, Krista A. Delviks-Frankenberry, Wei-Shau Hu
Publikováno v:
Journal of Virology. 84:5719-5729
Xenotropic murine leukemia virus-related virus (XMRV), a gammaretrovirus, has been isolated from human prostate cancer tissue and from activated CD4 + T cells and B cells of patients with chronic fatigue syndrome, suggesting an association between XM
Publikováno v:
Current HIV Research. 7:169-177
HIV-1 exploits the cellular machinery to replicate in the host cells by targeting a wide range of host factors at different stages of its life cycle. HIV-1 also induces detrimental effects in the infected and uninfected bystander cells resulting in d
Publikováno v:
Journal of Virology. 82:7189-7200
Human immunodeficiency virus type 1 (HIV-1) infection has been implicated in impairing various aspects of NK cell function in viremic condition, and several viral factors contribute to these defects. Here, we evaluated the effect of HIV-1 Vpr on NK c