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pro vyhledávání: '"Narasim Kasthurikrishnan"'
Autor:
Matthew L. Jorgensen, Bryan Li, Chiu Charles K, Richard A. Buzon, Stephen T. Colgan, Narasim Kasthurikrishnan
Publikováno v:
Tetrahedron Letters. 45:6887-6890
A short, efficient, and highly diastereoselective synthesis of 5-[(1S)-N-Boc-amino-(2S)-(3-fluorophenyl)ethyl]-dihydrofuran-2-one (1) is described. Use of phthalic anhydride as thiolate scavenger effectively preserves the chiral integrity of the α-a