Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Naoyuki Tahara"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Mutations in the SALL4 gene cause human syndromes with defects in multiple organs. Sall4 expression declines rapidly in post-gastrulation mouse embryos, and our understanding of the requirement of Sall4 in animal development is still limited
Externí odkaz:
https://doaj.org/article/ada8956bffef4fcd98ae5fa82504f6bc
Autor:
June Baik, Alessandro Magli, Naoyuki Tahara, Scott A. Swanson, Naoko Koyano-Nakagawa, Luciene Borges, Ron Stewart, Daniel J. Garry, Yasuhiko Kawakami, James A. Thomson, Rita C. R. Perlingeiro
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
How both BMP and Wnt signalling pathways regulate lineage specification early in development is unclear. Here, the authors show that endoglin via Jdp2, an AP-1 family member, modulates BMP and Wnt signalling to commit mesodermal progenitors to a haem
Externí odkaz:
https://doaj.org/article/2ffd9d9f384f4d06b3c823151dd71c1e
Autor:
Bhairab N Singh, Naoyuki Tahara, Yasuhiko Kawakami, Satyabrata Das, Naoko Koyano-Nakagawa, Wuming Gong, Mary G Garry, Daniel J Garry
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189010 (2017)
Remodeling of the primitive vasculature is necessary for the formation of a complex branched vascular architecture. However, the factors that modulate these processes are incompletely defined. Previously, we defined the role of microRNAs (miRNAs) in
Externí odkaz:
https://doaj.org/article/5f952302b3da4393b3be6148dfa367d4
Autor:
Shinichi Hayashi, Ryutaro Akiyama, Julia Wong, Naoyuki Tahara, Hiroko Kawakami, Yasuhiko Kawakami
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006138 (2016)
Gli3 is a major regulator of Hedgehog signaling during limb development. In the anterior mesenchyme, GLI3 is proteolytically processed into GLI3R, a truncated repressor form that inhibits Hedgehog signaling. Although numerous studies have identified
Externí odkaz:
https://doaj.org/article/7813bbfc08724ed2ae4a3dd532c1a096
Autor:
Yasuhiko Kawakami, Yasumasa Bessho, Hiroko Kawakami, Naoyuki Tahara, Ryutaro Akiyama, Justin Wang
Publikováno v:
Dev Biol
Zebrafish have a remarkable ability to regenerate the myocardium after injury by proliferation of pre-existing cardiomyocytes. Fibroblast growth factor (FGF) signaling is known to play a critical role in zebrafish heart regeneration through promotion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa27dde04e0b56643c6ddc422b951cec
https://doi.org/10.1016/j.ydbio.2020.12.019
https://doi.org/10.1016/j.ydbio.2020.12.019
Autor:
Yasuhiko Kawakami, Junji Itou, Paul Cavanah, Christine E. Salomon, Naoyuki Tahara, Yudi Rusman, Jessica Williams
Publikováno v:
Dev Dyn
BACKGROUND: The regeneration of larvae zebrafish fin emerged as a new model of regeneration in the last decade. In contrast to genetic tools to study fin regeneration, chemical probes to modulate and interrogate regeneration processes are not well de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769fecbfb7c547ace1506e686a944cf6
https://doi.org/10.1002/dvdy.244
https://doi.org/10.1002/dvdy.244
Autor:
Pier Paolo Pandolfi, Katherine Q. Chen, Naoyuki Tahara, Sho Kawakami, Yasuhiko Kawakami, Ryuichi Nishinakamura, Hiroko Kawakami, Aaron Anderson
Publikováno v:
Genetics
The vertebrate limb serves as an experimental paradigm to study mechanisms that regulate development of the stereotypical skeletal elements. In this study, we simultaneously inactivated Sall4 using Hoxb6Cre and Plzf in mouse embryos, and found that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdf37c62741a9b5c4e0f6f9a13f6555
https://europepmc.org/articles/PMC7198279/
https://europepmc.org/articles/PMC7198279/
Autor:
Hiroko Kawakami, Naoyuki Tahara, Julia Wong, Yasuhiko Kawakami, Ryutaro Akiyama, Joshua W.M. Theisen, Daniel J. Garry
Publikováno v:
Developmental Biology. 434:74-83
Isl1 is required for two processes during hindlimb development: initiation of the processes directing hindlimb development in the lateral plate mesoderm and configuring posterior hindlimb field in the nascent hindlimb buds. During these processes, Is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8171655a3aa1df7ed2d49e0b86c56e
https://doi.org/10.1016/j.ydbio.2017.11.013
https://doi.org/10.1016/j.ydbio.2017.11.013
Autor:
Hiroko Kawakami, Daniel J. Garry, Wuming Gong, Yasuhiko Kawakami, Aaron Anderson, Pruthvi Shah, Shinichi Hayashi, Malina Yamashita Peterson, Katherine Q. Chen, Ryuichi Nishinakamura, Naoyuki Tahara, Yasushi Nakagawa
Publikováno v:
Development
Bi-potential neuromesodermal progenitors (NMPs) produce both neural and paraxial mesodermal progenitors in the trunk and tail during vertebrate body elongation. We show that Sall4, a pluripotency-related transcription factor gene, has multiple roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab2c96584423f35f292fccb5e9b3a0e
https://doi.org/10.1242/dev.177659
https://doi.org/10.1242/dev.177659
Autor:
Hiroko Kawakami, Xiaodan Yu, Merissa Olmer, Anindya Bagchi, Shinichi Hayashi, Yasuhiko Kawakami, Naoyuki Tahara, Ryutaro Akiyama, Martin Lotz
Publikováno v:
Journal of Orthopaedic Research. 35:1671-1682
Increasing evidence supports the idea that bone morphogenetic proteins (BMPs) regulate cartilage maintenance in the adult skeleton. The aim of this study is to obtain insight into the regulation of BMP activities in the adult skeletal system. We anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a2c1281eaf09c73ccc00fefa9ff5b50
https://doi.org/10.1002/jor.23463
https://doi.org/10.1002/jor.23463