Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Naoyuki Iso-O"'
Autor:
Naoyuki Iso-o, Keisuke Komatsuya, Fuyuki Tokumasu, Noriko Isoo, Tomohiro Ishigaki, Hiroshi Yasui, Hiroshi Yotsuyanagi, Masumi Hara, Kiyoshi Kita
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Malaria parasites cannot multiply in host erythrocytes without cholesterol because they lack complete sterol biosynthesis systems. This suggests parasitized red blood cells (pRBCs) need to capture host sterols, but its mechanism remains unknown. Here
Externí odkaz:
https://doaj.org/article/35b4fa923b6744ca8196c1975c19e9bb
Autor:
Makoto Kurano, Masumi Hara, Koichi Tsuneyama, Koji Okamoto, Naoyuki Iso-O, Teruhiko Matsushima, Kazuhiko Koike, Kazuhisa Tsukamoto
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 11, Pp 2275-2285 (2012)
Niemann-Pick C1-like 1 protein (NPC1L1), a transporter crucial in intestinal cholesterol absorption, is expressed in human liver but not in murine liver. To elucidate the role of hepatic NPC1L1 on lipid metabolism, we overexpressed NPC1L1 in murine l
Externí odkaz:
https://doaj.org/article/7447357244564a1cacfb3b61ca739c16
Autor:
Yoshitaka Shiratori, Takashi Aoyagi, Tatsuru Yokoi, Seiji Nishide, Kentaro Kikuchi, Minoru Yoshida, Naoyuki Iso-O, Takahiro Kimura, Nobuaki Suzuki, Noriyuki Hayami, Tadashi Kohyama, Shinji Takahashi, Masumi Hara
Publikováno v:
Kansenshogaku Zasshi
We report the case of an 85-year-old woman who was transported to our hospital by ambulance with progressively worsening dyspnea and hypoxia She had no history of contact with any patient with coronavirus disease 2019 (COVID-19) The peripheral arteri
Autor:
Kengo Suzuki, Naoyuki Iso-O, Ayaka Nakashima, Tomoyuki Nariyama, Katsuyuki Matsui, Mizuki Yamano, Motoka Yagame, Yoshikuni Nagayama
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0237086 (2020)
PLoS ONE, Vol 15, Iss 8, p e0237086 (2020)
Paramylon is a novel β-glucan that is stored by Euglena gracilis Z, which is a unicellular photosynthesizing green alga with characteristics of both animals and plants. Recent studies have indicated that paramylon functions as an immunomodulator or
Autor:
Takaharu Yamada, Seigo Ito, Masumi Hara, Naoyuki Iso-O, Sonoka Hara, Anna Sugiura, Atsuko Takai, Kazuhisa Tsukamoto, Hideyuki Takeuchi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Background and Aims: Familial hypercholesterolemia (FH) is a high risk of developing premature coronary artery disease even in heterozygotes. It is reported that the diagnostic rate in Japan and the United States is extremely low compared with the Ne
Publikováno v:
The Biochemical journal. 475(12)
Apolipoprotein M (apoM) is a carrier and a modulator of sphingosine 1-phosphate (S1P), an important multifunctional bioactive lipid. Since peroxisome proliferator-activated receptor γ (PPARγ) is reportedly associated with the function and metabolis
Autor:
Naoyuki Iso-O, Hiroki Maeda, Masashi Oka, Mikitaka Iguchi, Takao Maekita, Kazuki Ueda, Kosaku Moribata, Izumi Inoue, Manabu Kawai, Kimihiko Yanaoka, Masao Ichinose, Jun Kato, Kiyokazu Shirai, Hironao Yasuoka, Hiroki Yamaue, Yasushi Nakamura, Naoki Shingaki, Hisanobu Deguchi, Hideyuki Tamai
Publikováno v:
Internal Medicine. 50:1689-1694
A 53-year-old woman was admitted because of a giant pancreatic tumor. Hypercalcemia and a high serum parathyroid hormone-related peptide (PTHrP) level were observed. A hypoglycemic attack occurred during pancreatectomy, and the surgical specimen reve
Autor:
Masumi Hara, Takashi Kadowaki, Naoyuki Iso-O, Kazuhisa Tsukamoto, Eisei Noiri, Kazuhiko Koike, Makoto Kurano
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 18:373-383
Aim Phytosterolemia is an inherited disorder characterized by hypercholesterolemia and premature atherosclerosis, together with increased inflammatory states in some cases. The underlying mechanisms of atherogenesis in phytosterolemia, however, have
Autor:
Makoto Watanabe, Yusuke Inoue, Takashi Nakaoka, Masaru Shinozaki, Hideki Ohno, Naoyuki Takahashi, Hitomi Nagayama, Naoki Oyaizu, Naohide Yamashita, Kazufumi Matsumoto, Fumitaka Nagamura, Naoyuki Iso-O
Publikováno v:
Clinical Journal of Gastroenterology. 3:307-317
Most pancreatic cancer patients are diagnosed at the advanced stages, and no therapy is superior to gemcitabine alone. To confirm the feasibility and efficacy of a novel clinical intervention using tumor vessel-specific anti-angiogenic peptide vaccin
Autor:
Naoyuki Iso-O, Kazuhiko Koike, Kazuhisa Tsukamoto, Masako Togo, Makoto Kurano, Masumi Hara, Yoshiaki Hashimoto, Takashi Kadowaki
Publikováno v:
Clinica Chimica Acta. 401:165-169
Background Phytosterolemia is one of the genetic disorders causing hypercholesterolemia and atherosclerosis together with the accumulation of plant sterol in plasma and tissues. The mutations in ABCG5 and ABCG8 genes, encoding sterolin-1 and -2, resp