Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Naoyuki Homma"'
Autor:
Teiichiro Honda, Teiichi Motoyama, Satoshi Nishizuka, Gen Tamura, Kanji So, Naoyuki Homma, Naoyuki Togawa, Takayoshi Waki
Publikováno v:
Cancer Science. 97:1155-1158
A number of tumor suppressor and tumor-related genes are silenced by promoter hypermethylation in gastric cancer. Hypermethylation is not restricted to cancer cells, but is also present in non-neoplastic cells during aging. Such age-related methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134a43f004a140a9e45b5ec036e57961
https://doi.org/10.1111/j.1349-7006.2006.00302.x
https://doi.org/10.1111/j.1349-7006.2006.00302.x
Autor:
Gen Tamura, Teiichiro Honda, Teiichi Motoyama, Masanori Terashima, Makoto Endoh, Naoyuki Homma, Satoshi Nishizuka
Publikováno v:
British Journal of Cancer
RASSF2, a member of the RASSF1 family, has recently been identified as a potential tumour suppressor. We examined methylation status in multiple regions which included the CpG island and spanned the transcription start site of RASSF2 in 10 gastric ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bac7551f3667c1ebcc7245e81574f41
https://doi.org/10.1038/sj.bjc.6602854
https://doi.org/10.1038/sj.bjc.6602854
Autor:
Gen Tamura, Teiichiro Honda, Teiichi Motoyama, Naoyuki Homma, Satoshi Nishizuka, Makoto Endoh, Naoyuki Togawa, Kanji So
Publikováno v:
Pathology international. 56(10)
Silencing of the RUNX3 gene by hypermethylation of its promoter CpG island plays a major role in gastric carcinogenesis. To quantitatively evaluate RUNX3 methylation, a fiber-type DNA microarray was used on which methylated and unmethylated sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824092a848137cbe69a5b49a22c1cd65
https://pubmed.ncbi.nlm.nih.gov/16984612
https://pubmed.ncbi.nlm.nih.gov/16984612
Autor:
Sumio Kawata, Teiichi Motoyama, Naoyuki Homma, Yutaka Matsumoto, Satoshi Nishizuka, Gen Tamura, Teiichiro Honda
Publikováno v:
Cancer science. 97(1)
RUNX3 is a novel tumor suppressor gene that is frequently silenced by promoter hypermethylation in gastric cancer. The methylation status of multiple regions within the RUNX3 promoter CpG island (3,478 bp) was examined in gastric cancer cell lines, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf34406b1e492f16b4ffb9237e4c28e
https://pubmed.ncbi.nlm.nih.gov/16367921
https://pubmed.ncbi.nlm.nih.gov/16367921
Autor:
Sumio Kawata, Zhe Jin, Kiyonari Ohmura, Naoyuki Homma, Teiichi Motoyama, Teiichiro Honda, Gen Tamura
Publikováno v:
Virchows Archiv : an international journal of pathology. 446(2)
Human tumors are genetically unstable, and the instability exists at two distinct levels—the chromosomal level and the nucleotide level. Chfr and hMLH1 hypermethylation, which may lead to chromosomal instability (CIN) and microsatellite instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e95769b32824d9aaf8b247f9166d32f
https://pubmed.ncbi.nlm.nih.gov/15735977
https://pubmed.ncbi.nlm.nih.gov/15735977