Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Naoya Yamada"'
Autor:
Naoya Yamada, Tadayoshi Karasawa, Junya Ito, Daisuke Yamamuro, Kazushi Morimoto, Toshitaka Nakamura, Takanori Komada, Chintogtokh Baatarjav, Yuma Saimoto, Yuka Jinnouchi, Kazuhisa Watanabe, Kouichi Miura, Naoya Yahagi, Kiyotaka Nakagawa, Takayoshi Matsumura, Ken-ichi Yamada, Shun Ishibashi, Naohiro Sata, Marcus Conrad, Masafumi Takahashi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Recent evidence indicates ferroptosis is implicated in the pathophysiology of various liver diseases; however, the organ-specific regulation mechanism is poorly understood. Here, we demonstrate 7-dehydrocholesterol reductase (DHCR7), the ter
Externí odkaz:
https://doaj.org/article/cf67912edd5e4955a7683d3553f31fd5
Autor:
Akihiko Miyauchi, Chika Watanabe, Naoya Yamada, Eriko F. Jimbo, Mizuki Kobayashi, Natsumi Ohishi, Atsuko Nagayoshi, Shiho Aoki, Yoshihito Kishita, Akira Ohtake, Nobuhiko Ohno, Masafumi Takahashi, Takanori Yamagata, Hitoshi Osaka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Originally, apomorphine was a broad-spectrum dopamine agonist with an affinity for all subtypes of the Dopamine D1 receptor to the D5 receptor. We previously identified apomorphine as a potential therapeutic agent for mitochondrial diseases
Externí odkaz:
https://doaj.org/article/4c4ab5e04fb84b9b860c3d9589244955
Autor:
Hiroshi Maeda, Kouichi Miura, Kenichi Aizawa, Oyunjargal Bat-Erdene, Miho Sashikawa-Kimura, Eri Noguchi, Masako Watanabe, Naoya Yamada, Hitoshi Osaka, Naoki Morimoto, Hironori Yamamoto
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 805 (2024)
The role of ferroptosis in steatohepatitis development is largely unknown. We investigated (1) whether hepatocyte ferroptosis occurs in a gene-modified steatohepatitis model without modifying dietary components, (2) whether ferroptosis occurs at an e
Externí odkaz:
https://doaj.org/article/5891026946694f0a9fb4b82f3f8875c0
Autor:
Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Emi Aizawa, Yoshiko Mizushina, Sachiko Watanabe, Chintogtokh Baatarjav, Takayoshi Matsumura, Masafumi Takahashi
Publikováno v:
eLife, Vol 11 (2022)
Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory syndrome caused by mutations of NLRP3 gene encoding cryopyrin. Familial cold autoinflammatory syndrome, the mildest form of CAPS, is characterized by cold-induced inflammation induc
Externí odkaz:
https://doaj.org/article/54eab856f68542b9915d303cd6a17e23
Autor:
Yuta Hirata, Yukihiro Sanada, Takahiko Omameuda, Takumi Katano, Go Miyahara, Naoya Yamada, Noriki Okada, Yasuharu Onishi, Yasunaru Sakuma, Naohiro Sata
Publikováno v:
Surgical Case Reports, Vol 6, Iss 1, Pp 1-4 (2020)
Abstract Background There have been no reports on the effectiveness of the administration of antithrombin III (AT III) for post-transplant portal vein thrombosis (PVT). We herein report a case of post-transplant PVT that was resolved by AT III treatm
Externí odkaz:
https://doaj.org/article/0a1c9e8315e243c9b4cd74f2fca1c821
Autor:
Naoya Yamada, Tadayoshi Karasawa, Hiroaki Kimura, Sachiko Watanabe, Takanori Komada, Ryo Kamata, Ariunaa Sampilvanjil, Junya Ito, Kiyotaka Nakagawa, Hiroshi Kuwata, Shuntaro Hara, Koichi Mizuta, Yasunaru Sakuma, Naohiro Sata, Masafumi Takahashi
Publikováno v:
Cell Death and Disease, Vol 11, Iss 2, Pp 1-16 (2020)
Abstract Acetaminophen (APAP) overdose is a common cause of drug-induced acute liver failure. Although hepatocyte cell death is considered to be the critical event in APAP-induced hepatotoxicity, the underlying mechanism remains unclear. Ferroptosis
Externí odkaz:
https://doaj.org/article/4c3e813c18814f5e811902c02c3b7717
Autor:
Emi Aizawa, Tadayoshi Karasawa, Sachiko Watanabe, Takanori Komada, Hiroaki Kimura, Ryo Kamata, Homare Ito, Erika Hishida, Naoya Yamada, Tadashi Kasahara, Yoshiyuki Mori, Masafumi Takahashi
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Pyroptosis is a form of regulated cell death that is characterized by gasdermin processing and increased membrane permeability. Caspase-1 and caspase-11 have been considered to be essential for gasdermin D processing associated with inflamma
Externí odkaz:
https://doaj.org/article/b76dceaede2544eaac2ccc4136359c28
Autor:
Kenta Fujimura, Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Yoshiko Mizushina, Chintogtokh Baatarjav, Takayoshi Matsumura, Kinya Otsu, Norihiko Takeda, Hiroaki Mizukami, Kazuomi Kario, Masafumi Takahashi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 180:58-68
Autor:
Chintogtokh Baatarjav, Takanori Komada, Tadayoshi Karasawa, Naoya Yamada, Ariunaa Sampilvanjil, Takayoshi Matsumura, Masafumi Takahashi
Publikováno v:
Cell Death & Differentiation. 29:2487-2502
Rhabdomyolysis is a severe condition that commonly leads to acute kidney injury (AKI). While double-stranded DNA (dsDNA) released from injured muscle can be involved in its pathogenesis, the exact mechanism of how dsDNA contributes to rhabdomyolysis-
Autor:
Yoshiyuki Watanabe, Mutsuto Kato, Toru Yahagi, Hiroki Murayama, Naoya Yamada, Kenichi Yoshida, Kenichi Maehara, Yusuke Fukuda, Kazuyuki Sashida, Katsuya Ikeda, Kosuke Ikeda, Toshiyuki Takemori
Publikováno v:
Electrical Engineering in Japan. 215