Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Naoya Hatanaka"'
Publikováno v:
Mathematical and Computational Applications, Vol 29, Iss 4, p 62 (2024)
This study analyzed the non-canonical NF-κB pathway, which controls functions distinct from those of the canonical pathway. Although oscillations of NF-κB have been observed in the non-canonical pathway, a detailed mechanism explaining the observed
Externí odkaz:
https://doaj.org/article/8632845285314d8baa26841add8d3dcc
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The LUBAC ubiquitin ligase complex, composed of the HOIP, HOIL-1L, and SHARPIN subunits, stimulates the canonical nuclear factor-κB (NF-κB) activation pathways through its Met1-linked linear ubiquitination activity. Here we performed cellular and m
Externí odkaz:
https://doaj.org/article/e2657da246c14eab95686eafba17f02d
Publikováno v:
Springer Proceedings in Mathematics & Statistics ISBN: 9789811648656
The linear ubiquitin chain assembly complex (LUBAC), composed of the HOIP, HOIL-1L, and SHARPIN subunits, activates the canonical nuclear factor-κB (NF-κB) pathway through the Met1 (M1)-linked linear ubiquitination activity. On the course of the T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e48b1f95e53e34a6baf7ba1bc66255
https://doi.org/10.1007/978-981-16-4866-3_14
https://doi.org/10.1007/978-981-16-4866-3_14
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
The LUBAC ubiquitin ligase complex, composed of the HOIP, HOIL-1L, and SHARPIN subunits, stimulates the canonical nuclear factor-κB (NF-κB) activation pathways through its Met1-linked linear ubiquitination activity. Here we performed cellular and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0621c3073942e1c79f237698a5eb062d
https://doi.org/10.3389/fimmu.2020.601926
https://doi.org/10.3389/fimmu.2020.601926
Publikováno v:
Hepatology international. 12(3)
Safety and effectiveness of daclatasvir (DCV)/asunaprevir (ASV) dual therapy were demonstrated in Japanese patients with chronic hepatitis C (CHC) genotype (GT) 1b in phase III studies. This postmarketing surveillance (PMS) was conducted to assess th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18683b8766287a16d61728c24b679537
https://pubmed.ncbi.nlm.nih.gov/29900486
https://pubmed.ncbi.nlm.nih.gov/29900486
Autor:
Kiyoshi Kubota, Toshiaki Nakamura, Naoya Hatanaka, Kotonari Aoki, Mayumi Mochizuki, Akira Kokan, Hisashi Urushihara, Tatsuo Kagimura, Takeshi Hirakawa, Shigeru Kageyama, Daisuke Koide, Tsugumichi Sato, Ken Nakajima, Kou Miyakawa
Publikováno v:
Japanese Journal of Pharmacoepidemiology/Yakuzai ekigaku. 19:57-74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d60d7ed51d5cb4e438afea97c254c40
https://doi.org/10.3820/jjpe.19.57
https://doi.org/10.3820/jjpe.19.57
Autor:
Satoru Asahi, Noriaki Shimada, Tomoko Komatsu, Mami Nakamura, Tsuyoshi Yokoi, Tsutomu Shimada, Naoya Hatanaka, Hiroshi Yamazaki, F. Peter Guengerich, Katsuhiro Ohyama, Miki Nakajima
Publikováno v:
Protein Expression and Purification. 24:329-337
Drug oxidation activities of 12 recombinant human cytochrome P450s (P450) coexpressed with human NADPH-P450 reductase (NPR) in bacterial membranes (P450/NPR membranes) were determined and compared with those of other recombinant systems and those of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db0c2e33e5dd583bbc490896a60c437
https://doi.org/10.1006/prep.2001.1578
https://doi.org/10.1006/prep.2001.1578
Autor:
Hiroshi Yamazaki, Yoshimitsu Oda, Tsuyoshi Yokoi, Naoya Hatanaka, F. Peter Guengerich, Miki Nakajima
Publikováno v:
Mutation research. 497(1-2)
Metabolic activation of 1-nitropyrene (1-NP) by human cytochrome P450 (P450) family 1 enzymes co-expressed with NADPH-cytochrome P450 reductase (NPR) in Escherichia coli membranes was investigated. 1-NP induced umu gene expression in Salmonella typhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc98f3947b91ca0a80a426520b606e8d
https://pubmed.ncbi.nlm.nih.gov/11525925
https://pubmed.ncbi.nlm.nih.gov/11525925
Autor:
Yasunobu Aoki, Ryoichi Kizu, Naoya Hatanaka, Tsuyoshi Yokoi, Hiroshi Yamazaki, Miki Nakajima, Kazuichi Hayakawa, Masashi Iwanari
Publikováno v:
Scopus-Elsevier
We have shown previously that diesel exhaust particle (DEP) extracts (DEPE) and 1-nitropyrene were genotoxically activated by human cytochrome P450 1B1 in SOS/ umu assay. In this study, the in vivo induction of P450 family 1 enzymes in rats by exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a8a43ebadf698820441f0224c14196
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035681572&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035681572&partnerID=MN8TOARS