Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Naoya Aoo"'
Autor:
Masahiko Funada, Naoya Aoo
Publikováno v:
Folia Pharmacologica Japonica. 130:128-133
薬物が示す多幸感および陶酔感を経験し,薬物乱用を繰り返すことにより「自己制御が困難になった生物学的状況」を薬物依存(drug dependence)という.薬物依存という概念は,薬物を欲
Autor:
Tsuyomu Ikenoue, Katsunori Iwasaki, Naoya Aoo, Kenichi Mishima, Tomoaki Ikeda, An Xin Liu, Nobuaki Egashira, Michihiro Fujiwara
Publikováno v:
American Journal of Obstetrics and Gynecology. 192:719-726
Objective There are no established therapies for preventing or rescuing perinatal infection or inflammation-induced perinatal brain damage. We administered dexamethasone (DEX), a synthetic corticosteroid anti-inflammatory drug, to neonatal rats in a
Autor:
Tomoaki Ikeda, Kenichi Mishima, Tsuyomu Ikenoue, Naoya Aoo, Nobuaki Egashira, Michihiro Fujiwara, Katsunori Iwasaki
Publikováno v:
American Journal of Obstetrics and Gynecology. 191:2132-2141
Objective We assessed the long-term effects of perinatal hypoxia-ischemia and endotoxin on attention and short- and long-term memory in neonatal rats with the use of behavioral tasks and brain histologic results. Study design Four hours after injecti
Autor:
Tsuyomu Ikenoue, Michihiro Fujiwara, Katsunori Iwasaki, Tetsuya Yoshikawa, Kenichi Mishima, Yi X. Xia, Nobuaki Egashira, Naoya Aoo, Tomoaki Ikeda
Publikováno v:
Behavioural Brain Research. 151:209-217
We previously reported that rats exposed to neonatal hypoxic-ischemic (HI) insult showed selective and long-lasting learning and memory impairments in the plus maze, 8-arm radial maze, choice reaction time (CRT) task, and water maze, and that they sh
Autor:
Tsuyomu Ikenoue, Katsunori Iwasaki, Hidenobu Ochiai, Shinichiro Wakisaka, Naoya Aoo, Tomoaki Ikeda, Kenichi Mishima, Michihiro Fujiwara, Shinichi Nakano
Publikováno v:
Neurosurgery. 53:973-978
Objective We sought to evaluate from a behavioral and histological viewpoint the effect of local administration of glial cell line-derived neurotrophic factor (GDNF) on neonatal preganglionic Erb's palsy in rats. Methods The Erb's palsy model was pro
Autor:
Kenichi Mishima, Nobuaki Egashira, Michihiro Fujiwara, Katsunori Iwasaki, Yukihiro Shoyama, Tetsuya Yoshikawa, Megumi Fujii, Yoshihiko Fukue, Naoya Aoo, Yoko Honda
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:1570-1576
Activating the noradrenergic and cholinergic systems is known to enhance attentional processes, while stimulating dopaminergic, serotonergic, and GABAergic systems suppresses them. The objective of the present study was to investigate the pharmacolog
Publikováno v:
Journal of Addiction Research & Therapy.
Background: N-methyl-1-(4-methoxyphenyl)-2-aminopropane (para-methoxymethamphetamine, PMMA) is a structurally abbreviated congener of methamphetamine that is abused as a “designer drug”. The aim of the present study was to investigate the behavio
Autor:
Masahiro Tsuji, Keiichi Irie, Michihiro Fujiwara, Kenichi Mishima, Tomoaki Ikeda, Yoshiharu Akitake, Kazuhiro Harada, Naoya Aoo, Yuya Sakamoto
Publikováno v:
Experimental neurology. 226(2)
Much effort and many resources are being devoted to rehabilitative programs for children with disabilities caused by neonatal hypoxic-ischemic encephalopathy without clear evidence of the efficacy of such programs. We recently reported that rehabilit
Publikováno v:
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studiesdrug dependence. 43(5)
The conditioned place preference paradigm has been used to evaluate the motivational effects of drugs. The primary motivational effects of a drug are conditioned to prominent environmental stimuli of a conditioned place preference box, and after seve
Publikováno v:
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. 28(1)
Abuse of volatile organic solvents among youth remains a major social problem. Organic solvents are cheap and relatively easy to obtain, so they carry the risk of becoming a "gateway drug" for users. The effect of repeated inhalation of toluene on su