Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Naoya, Ohara"'
Autor:
Amina K. Shaban, Gebremichal Gebretsadik, Mariko Hakamata, Hayato Takihara, Erina Inouchi, Akihito Nishiyama, Yuriko Ozeki, Yoshitaka Tateishi, Yukiko Nishiuchi, Takehiro Yamaguchi, Naoya Ohara, Shujiro Okuda, Sohkichi Matsumoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Survival of the live attenuated Bacillus Calmette-Guérin (BCG) vaccine amidst harsh host environments is key for BCG effectiveness as it allows continuous immune response induction and protection against tuberculosis. Mycobacterial DNA bind
Externí odkaz:
https://doaj.org/article/61dd04c5205849a3bb027beab3339312
Autor:
Keiichi Taniguchi, Daisuke Hayashi, Naomi Yasuda, Mao Nakayama, Kaori Yazawa, Shouta Ogawa, Yuji Miyatake, Saki Suda, Haruka Tomita, Miki Tokuda, Saotomo Itoh, Jun-ichi Maeyama, Naoya Ohara, Saburo Yamamoto, Shigeaki Hida, Kikuo Onozaki, Takemasa Takii
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
This study revealed the difference of in vivoin vitro
Externí odkaz:
https://doaj.org/article/82b91fda4cfe41feb7f66bdef691d50b
Autor:
Eiki Yamachika, Yuichi Matsui, Masakazu Matsubara, Tatsushi Matsumura, Naoki Nakata, Norifumi Moritani, Atsushi Ikeda, Hidetsugu Tsujigiwa, Naoya Ohara, Seiji Iida
Publikováno v:
Journal of Dental Sciences, Vol 12, Iss 4, Pp 333-339 (2017)
Background/purpose: Few studies have investigated the possibility that bisphosphonate-related osteonecrosis of the jaw (BRONJ) might reflect an immune response; however, gamma delta T cells have been shown to significantly decline in the blood of BRO
Externí odkaz:
https://doaj.org/article/55dde2bfe2f64f2e8ce943b8aac9e97f
Autor:
Masaaki Nakayama, Naoya Ohara
Publikováno v:
Japanese Dental Science Review, Vol 53, Iss 4, Pp 134-140 (2017)
Porphyromonas gingivalis (P. gingivalis) is a major oral pathogen and associated with periodontal diseases including periodontitis and alveolar bone loss. In this review, we indicate that two virulence factors, which are hemoglobin receptor protein (
Externí odkaz:
https://doaj.org/article/af8c4be94d494cccaaed943095529db7
Autor:
Takayuki Matsumura, Tadayoshi Ikebe, Koji Arikawa, Masahito Hosokawa, Michio Aiko, Aoi Iguchi, Ikuko Togashi, Sayaka Kai, Sakiko Ohara, Naoya Ohara, Makoto Ohnishi, Haruo Watanabe, Kazuo Kobayashi, Haruko Takeyama, Sho Yamasaki, Yoshimasa Takahashi, Manabu Ato
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 561-571.e6 (2019)
Summary: Severe invasive group A Streptococcus (GAS) infection evades anti-bacterial immunity by attenuating the cellular components of innate immune responses. However, this loss of protection is compensated for by interferon (IFN)-γ-producing imma
Externí odkaz:
https://doaj.org/article/c50eebe37130461e86dfae29f91fefcc
Publikováno v:
The Journal of Immunology. 208:1146-1154
Porphyromonas gingivalis is commonly known as one of the major pathogens contributing to periodontitis, and its persistent infection may increase the risk for the disease. The proinflammatory mediators, including IL-6, TNF-α, and cyclooxygenase-2 (C
Autor:
Naoya Ohara, Norifumi Kawakami, Ryoichi Arai, Naruhiko Adachi, Toshio Moriya, Masato Kawasaki, Kenji Miyamoto
Publikováno v:
Journal of the American Chemical Society.
Protein nanocages are of increasing interest for use as drug capsules, but the encapsulation and release of drug molecules at appropriate times require the reversible association and dissociation of the nanocages. One promising approach to addressing
Autor:
Shoichi Mitsunaka, Kohei Yamazaki, Ajeng K. Pramono, Megumi Ikeuchi, Tomoe Kitao, Naoya Ohara, Tomoko Kubori, Hiroki Nagai, Hiroki Ando
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The serious threats posed by drug-resistant bacterial infections and recent developments in synthetic biology have fueled a growing interest in genetically engineered phages with therapeutic potential. To date, many investigations on engineered phage
Attempt of thyX gene silencing and construction of a thyX deleted clone in a Mycobacterium bovis BCG
Autor:
Yuki Arimura, Nao Hirata, Takayuki Wada, Masaaki Nakayama, Yasuhiko Suzuki, Ayako Ryu-Mon, Chie Nakajima, Naoya Ohara, Seiji Iida, Manabu Ato, Kazuo Kobayashi, Yusuke Minato, Naoko Ohara
Publikováno v:
Microbiology and Immunology. 66(1):10-14
Mycobacterium tuberculosis, the causative agent of tuberculosis, possess flavin-dependent thymidylate synthase, ThyX. Since thyX is absent in humans and was shown to be essential for M. tuberculosis normal growth, ThyX is thought to be an attractive
Publikováno v:
Protein Expression and Purification. 205:106232