Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Naouale El Yamani"'
Autor:
Marc Audebert, Ann-Sophie Assmann, Amaya Azqueta, Pavel Babica, Emilio Benfenati, Sylvie Bortoli, Peter Bouwman, Albert Braeuning, Tanja Burgdorf, Xavier Coumoul, Kloé Debizet, Maria Dusinska, Norman Ertych, Jörg Fahrer, Verena Fetz, Ludovic Le Hégarat, Adela López de Cerain, Harm J. Heusinkveld, Kevin Hogeveen, Miriam N. Jacobs, Mirjam Luijten, Giuseppa Raitano, Cynthia Recoules, Elise Rundén-Pran, Mariam Saleh, Iva Sovadinová, Martina Stampar, Lea Thibol, Céline Tomkiewicz, Ariane Vettorazzi, Bob Van de Water, Naouale El Yamani, Bojana Zegura, Michael Oelgeschläger
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays. Fo
Externí odkaz:
https://doaj.org/article/bb67b7cd857c45a58747146a121d489d
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The Alamar Blue (AB) assay is widely used to investigate cytotoxicity, cell proliferation and cellular metabolic activity within different fields of toxicology. The use of the assay with nanomaterials (NMs) entails specific aspects including the pote
Externí odkaz:
https://doaj.org/article/0a3f2ab915a34481af0b110bfb87f664
Autor:
Elise Rundén-Pran, Espen Mariussen, Naouale El Yamani, Elisabeth Elje, Eleonora Marta Longhin, Maria Dusinska
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
To cope with the high number of nanomaterials manufactured, it is essential to develop high-throughput methods for in vitro toxicity screening. At the same time, the issue with interference of the nanomaterial (NM) with the read-out or the reagent of
Externí odkaz:
https://doaj.org/article/323d16bd0a264659a179d9d682a3f63d
Autor:
Verona Buocikova, Eleonora Marta Longhin, Eleftherios Pilalis, Chara Mastrokalou, Svetlana Miklikova, Marina Cihova, Alexandra Poturnayova, Katarina Mackova, Andrea Babelova, Lenka Trnkova, Naouale El Yamani, Congying Zheng, Ivan Rios-Mondragon, Martina Labudova, Lucia Csaderova, Kristina Mikus Kuracinova, Peter Makovicky, Lucia Kucerova, Miroslava Matuskova, Mihaela Roxana Cimpan, Maria Dusinska, Pavel Babal, Aristotelis Chatziioannou, Alena Gabelova, Elise Rundén-Pran, Bozena Smolkova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 147, Iss , Pp 112662- (2022)
Acquired drug resistance and metastasis in breast cancer (BC) are coupled with epigenetic deregulation of gene expression. Epigenetic drugs, aiming to reverse these aberrant transcriptional patterns and sensitize cancer cells to other therapies, prov
Externí odkaz:
https://doaj.org/article/1345e26c32b84eee948affb57a4afc4c
Autor:
Antreas Afantitis, Georgia Melagraki, Panagiotis Isigonis, Andreas Tsoumanis, Dimitra Danai Varsou, Eugenia Valsami-Jones, Anastasios Papadiamantis, Laura-Jayne A. Ellis, Haralambos Sarimveis, Philip Doganis, Pantelis Karatzas, Periklis Tsiros, Irene Liampa, Vladimir Lobaskin, Dario Greco, Angela Serra, Pia Anneli Sofia Kinaret, Laura Aliisa Saarimäki, Roland Grafström, Pekka Kohonen, Penny Nymark, Egon Willighagen, Tomasz Puzyn, Anna Rybinska-Fryca, Alexander Lyubartsev, Keld Alstrup Jensen, Jan Gerit Brandenburg, Stephen Lofts, Claus Svendsen, Samuel Harrison, Dieter Maier, Kaido Tamm, Jaak Jänes, Lauri Sikk, Maria Dusinska, Eleonora Longhin, Elise Rundén-Pran, Espen Mariussen, Naouale El Yamani, Wolfgang Unger, Jörg Radnik, Alexander Tropsha, Yoram Cohen, Jerzy Leszczynski, Christine Ogilvie Hendren, Mark Wiesner, David Winkler, Noriyuki Suzuki, Tae Hyun Yoon, Jang-Sik Choi, Natasha Sanabria, Mary Gulumian, Iseult Lynch
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 583-602 (2020)
Nanotechnology has enabled the discovery of a multitude of novel materials exhibiting unique physicochemical (PChem) properties compared to their bulk analogues. These properties have led to a rapidly increasing range of commercial applications; this
Externí odkaz:
https://doaj.org/article/81b6870ad37945198bc7dfd358f34de2
Autor:
Yvonne Kohl, Elise Rundén-Pran, Espen Mariussen, Michelle Hesler, Naouale El Yamani, Eleonora Marta Longhin, Maria Dusinska
Publikováno v:
Nanomaterials, Vol 10, Iss 10, p 1911 (2020)
Changes in the genetic material can lead to serious human health defects, as mutations in somatic cells may cause cancer and can contribute to other chronic diseases. Genotoxic events can appear at both the DNA, chromosomal or (during mitosis) whole
Externí odkaz:
https://doaj.org/article/8cc53abe0f394ff7b215d8563aa07897
Autor:
Alena Kazimirova, Naouale El Yamani, Laura Rubio, Alba García-Rodríguez, Magdalena Barancokova, Ricard Marcos, Maria Dusinska
Publikováno v:
Nanomaterials, Vol 10, Iss 3, p 465 (2020)
The genotoxicity of anatase/rutile TiO2 nanoparticles (TiO2 NPs, NM105 at 3, 15 and 75 µg/cm2) was assessed with the mammalian in-vitro Hypoxanthine guanine phosphoribosyl transferase (Hprt) gene mutation test in Chinese hamster lung (V79) fibroblas
Externí odkaz:
https://doaj.org/article/6c87b382ab3e48bda1d4eeb5fb0cf2a3
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
We used the alkaline protocol of the modified plant comet assay for rapid detection of DNA damage in potato plants exposed to low (50 mmol l-1), moderate (100 mmol l-1) and high (200 mmol l-1) NaCl stress in hydroponic conditions. DNA damage was meas
Externí odkaz:
https://doaj.org/article/66f1ebe5b6e94310be70981a4f48b9d1
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
The unique physicochemical properties of engineered nanomaterials (NMs) have accelerated their use in diverse industrial and domestic products. Although their presence in consumer products represents a major concern for public health safety, their po
Externí odkaz:
https://doaj.org/article/ebb2290d74e14d2e8d768c71a5f71e7b
Autor:
Andrew Collins, Peter Møller, Goran Gajski, Soňa Vodenková, Abdulhadi Abdulwahed, Diana Anderson, Ezgi Eyluel Bankoglu, Stefano Bonassi, Elisa Boutet-Robinet, Gunnar Brunborg, Christy Chao, Marcus S. Cooke, Carla Costa, Solange Costa, Alok Dhawan, Joaquin de Lapuente, Cristian Del Bo’, Julien Dubus, Maria Dusinska, Susan J. Duthie, Naouale El Yamani, Bevin Engelward, Isabel Gaivão, Lisa Giovannelli, Roger Godschalk, Sofia Guilherme, Kristine B. Gutzkow, Khaled Habas, Alba Hernández, Oscar Herrero, Marina Isidori, Awadhesh N. Jha, Siegfried Knasmüller, Ingeborg M. Kooter, Gudrun Koppen, Marcin Kruszewski, Carina Ladeira, Blanca Laffon, Marcelo Larramendy, Ludovic Le Hégarat, Angélique Lewies, Anna Lewinska, Guillermo E. Liwszyc, Adela López de Cerain, Mugimane Manjanatha, Ricard Marcos, Mirta Milić, Vanessa Moraes de Andrade, Massimo Moretti, Damian Muruzabal, Matjaž Novak, Rui Oliveira, Ann-Karin Olsen, Norah Owiti, Mário Pacheco, Alok K. Pandey, Stefan Pfuhler, Bertrand Pourrut, Kerstin Reisinger, Emilio Rojas, Elise Rundén-Pran, Julen Sanz-Serrano, Sergey Shaposhnikov, Ville Sipinen, Karen Smeets, Helga Stopper, João Paulo Teixeira, Vanessa Valdiglesias, Mahara Valverde, Frederique van Acker, Frederik-Jan van Schooten, Marie Vasquez, Johannes F. Wentzel, Maciej Wnuk, Annelies Wouters, Bojana Žegura, Tomas Zikmund, Sabine A. S. Langie, Amaya Azqueta
Publikováno v:
Nature Protocols
Nature Protocols, 2023, ⟨10.1038/s41596-022-00754-y⟩
Nature Protocols. Nature Publishing Group
Nat Protoc
Nature Protocols, 2023, ⟨10.1038/s41596-022-00754-y⟩
Nature Protocols. Nature Publishing Group
Nat Protoc
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. The types of damage detected encompass DNA strand breaks and alkali-labile sites (e.g., apurinic/apyrimidinic sites), alkylated an