Zobrazeno 1 - 10
of 551
pro vyhledávání: '"Naoto Oku"'
Autor:
Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu, Kazuhiro Saito, Ikumi Yamauchi, Saki Ariizumi, Yuqi Zhou, Ting-Hui Xiao, Keisuke Goda, Naoto Oku, Tomohiro Asai, Kenneth J. Shea
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Sepsis caused by the release of inflammatory mediators into the blood is a life threatening disease. Here, the authors report on the development of hydrogel nanoparticles for the capture and neutralisation of histones, major inflammatory mediators, a
Externí odkaz:
https://doaj.org/article/eb612ef6ea67468793984170be09b6f2
Autor:
Hiroyuki Koide, Kazuhiro Saito, Keiichi Yoshimatsu, Beverly Chou, Yu Hoshino, Sei Yonezawa, Naoto Oku, Tomohiro Asai, Kenneth J. Shea
Publikováno v:
Journal of Controlled Release. 355:745-759
Autor:
Minoru Numata, Akane Hirano, Yukika Yamamoto, Michiko Yasuda, Nobuhiko Miura, Kazutoshi Sayama, Masa-Aki Shibata, Tomohiro Asai, Naoto Oku, Noriyuki Miyoshi, Kayoko Shimoi
Publikováno v:
Journal of Circadian Rhythms, Vol 19, Iss 1 (2021)
Epidemiological studies have indicated that a disturbed circadian rhythm resulting from night-shift work is a potential risk factor for breast cancer. However, the mechanism of increased risk of breast cancer by night-shift work remains unclear, and
Externí odkaz:
https://doaj.org/article/04e209f79b64459b8c60ccc245e848e8
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 361 (2022)
Ischemic stroke is still one of the leading causes of high mortality and severe disability worldwide. Therapeutic options for ischemic stroke and subsequent cerebral ischemia/reperfusion injury remain limited due to challenges associated with drug pe
Externí odkaz:
https://doaj.org/article/b3c27f17c4064d0eb3160f8399ae9b2b
Autor:
Liqing Zang, Yasuhito Shimada, Hiroko Nakayama, Wenbiao Chen, Ayaka Okamoto, Hiroyuki Koide, Naoto Oku, Takehisa Dewa, Masayuki Shiota, Norihiro Nishimura
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Type 2 diabetes mellitus (T2DM) is characterized by persistent hyperglycemia and is influenced by genetic and environmental factors. Optimum T2DM management involves early diagnosis and effective glucose-lowering therapies. Further research is warran
Externí odkaz:
https://doaj.org/article/a6d9febec8aa4a38b51628dd248b7115
Autor:
Tomohiro Asai, Masafumi Yokota, Hideki Isomura, Hiroyuki Koide, Naoyuki Sakurai, Ayaka Okamoto, Hidenori Ando, Takehisa Dewa, Naoto Oku
Publikováno v:
Journal of Pharmaceutical Sciences.
Autor:
Ken-ichi Mawatari, Yuika Tanikawa, Makoto Yasuda, Tomoko Fukuuchi, Noriko Yamaoka, Kiyoko Kaneko, Kazuya Nakagomi, Naoto Oku
Publikováno v:
International Journal of Tryptophan Research; Jan-Dec2023, Vol. 16, p1-6, 6p
Autor:
Naoto Oku, Shungo Goto, Kazuki Agata, Yasuhiro Magata, Yudai Narita, Tomohiro Asai, Shohei Takasugi, Kosuke Shimizu
Publikováno v:
Journal of Controlled Release. 335:389-397
As current treatments for multiple sclerosis (MS) remain chemotherapeutic ones directed toward symptoms, the development of a curative treatment is urgently required. Herein, we show an autoreactive immune celltargetable approach using autoantigen-mo
Autor:
Hiromichi Egami, Naoto Oku, Anna Okishima, Yoshitaka Hamashima, Go Yasuno, Hiroyuki Koide, Yu Hoshino, Tomohiro Asai, Naoki Hayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 561:1-6
Synthetic polymers prepared using several functional monomers have attracted attention as cost-effective protein affinity reagents and alternative to antibodies. We previously reported the synthesis of poly NIPAm-based nanoparticles (NPs) using sever
Autor:
Yoshitaka Hamashima, Hiroyuki Koide, Hikaru Suzuki, Hiroki Ochiai, Naoto Oku, Tomohiro Asai, Hiromichi Egami
Publikováno v:
Biochemical and Biophysical Research Communications. 555:32-39
Protein–protein (e.g., antibody–antigen) interactions comprise multiple weak interactions. We have previously reported that lipid nanoparticles (LNPs) bind to and neutralize target toxic peptides after multifunctionalization of the LNP surface (M