Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Naoto Kakinuma"'
Autor:
Takehiro Suzuki, Atsushi Kondo, Naoto Kakinuma, Shiro Kambe, Hirotaka Takahashi, Kazuyuki Maeda, Yuta Matsushima
Publikováno v:
Solid State Ionics. 308:101-106
The oxygen deficiency of SnO 2 was investigated by thermogravimetric analysis (TGA). The powder samples were reduced in 0.5% H 2 /N 2 at 200–500 °C and, their weight changes were evaluated by TGA under flowing O 2 . The results showed that the res
Autor:
Sen Takeda, Soo Hyun Jo, Satoshi Arai, Chihiro Adachi, Yusuke Arai, Takayuki Ishii, Tetsuya Kitaguchi, Takafumi Inoue, Naoto Kakinuma
Publikováno v:
J Biol Chem
Sonic hedgehog (SHH) is important for organogenesis during development. Recent studies have indicated that SHH is also involved in the proliferation and transformation of astrocytes to the reactive phenotype. However, the mechanisms underlying these
Autor:
Miwa Sohda, Naoto Kakinuma, Shinya Ueno, Yoshiko Haga, Kazuyoshi Watanabe, Shinichi Hirose, Yoshio Misumi, Bo Zhang, Sen Takeda, Atsushi Ishii, Takeshi Kanaumi, Motohiro Okada, Sachio Takashima, Sunao Kaneko
Publikováno v:
Epilepsy Research. 108:420-432
Mutations in GABRG2, which encodes the γ2 subunit of GABAA receptors, can cause both genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome. Most GABRG2 truncating mutations associated with Dravet syndrome result in premature termin
Publikováno v:
Experimental cell research. 353(2)
Chromosome instability, frequently found in cancer cells, is caused by a deficiency in cell division, including centrosomal amplification and cytokinesis failure, and can result in abnormal chromosome content or aneuploidy. The small GTPase pathways
Autor:
Naoto Kakinuma, Ryoiti Kiyama
Publikováno v:
Biochemical and Biophysical Research Communications. 386:639-644
Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is associated with heterozygous mutations in the KIF21A gene, including a major (R954W) and a minor (M947T) mutation. Kank1, which regulates actin polymerization, cell migration and neuri
Publikováno v:
The Journal of Cell Biology
In this study, insulin receptor substrate (IRS) p53 is identified as a binding partner for Kank, a kidney ankyrin repeat–containing protein that functions to suppress cell proliferation and regulate the actin cytoskeleton. Kank specifically inhibit
Publikováno v:
Journal of Cell Science. 119:4002-4010
The human Kank protein has a role in controlling the formation of the cytoskeleton by regulating actin polymerization. Besides the cytoplasmic localization as reported before, we observed the nuclear localization of Kank in OS-RC-2 cells. To uncover
Autor:
Chihiro Adachi1, Naoto Kakinuma2, Soo Hyun Jo1, Takayuki Ishii1, Yusuke Arai1, Satoshi Arai3,4, Tetsuya Kitaguchi3,5, Sen Takeda2, Takafumi Inoue1 inoue.t@waseda.jp
Publikováno v:
Journal of Biological Chemistry. 11/1/2019, Vol. 294 Issue 44, p16034-16048. 15p.
Autor:
Tetsu Akiyama, Susumu Ohwada, Motowo Nakajima, Masaaki Sato, Yasuhiko Shibanaka, Kazuyoshi Kohu, Tatsuya Yamada, Naoto Kakinuma
Publikováno v:
Cancer Science. 96:191-196
The improved IGCR (In-Gel Competitive Reassociation) method was applied to the analysis of human gastric cancer genomic DNA to identify its alterations, and it appeared that the IGCR library contained a fragment of 3'-untranslated region (3' UTR) of
Autor:
Motowo Nakajima, Naoto Kakinuma, Tatsuya Yamada, Masaaki Sato, Kazuyoshi Kohu, Susumu Ohwada, Yasuhiko Shibanaka, Tetsu Akiyama
Publikováno v:
SEIBUTSU BUTSURI KAGAKU. 48:25-30
In-gel competitive reassociation (IGCR) technique is one of the DNA subtraction methods with a high capacity. We have improved the IGCR technique and overcame several disadvantages such as time-consuming and complex process with poor reproducibility.