Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease.

Autor: Naoto Kadoguchi¹ naoto_kadoguchi@khsc.or.jp, Shinji Okabe¹ action_0ru3r01578x1f1v@yahoo.co.jp, Yukio Yamamura¹ c401331031@tokushima-u.ac.jp, Misaki Shono¹ c401103042@tokushima-u.ac.jp, Tatsuya Fukano¹ qqq645gd@gmail.com, Akie Tanabe¹ t-aki-falcon@kmail.plala.or.jp, Hironori Yokoyama¹ nokky1219@yahoo.co.jp, Jiro Kasahara¹ awajiro@tokushima-u.ac.jp

Publikováno v: BMC Neuroscience. 2014, Vol. 15 Issue 1, p1-27. 27p. 1 Black and White Photograph, 1 Diagram, 1 Chart, 6 Graphs.

Systemic Administration of Proteasome Inhibitor Protects Against MPTP Neurotoxicity in Mice

Autor: Hayato Kuroiwa, Naoto Kadoguchi, Ryohei Yano, Takuya Oshikawa, Hironori Yokoyama, Hiroyuki Kato, Tsutomu Araki

Publikováno v: Cellular and Molecular Neurobiology. 29:769-777

Dysfunction of the proteasome has been suggested to contribute in the degeneration of nigrostriatal dopaminergic neurons. Here, we investigated to determine whether systematic administration of proteasome inhibitor, carbobenzoxy-L: -gamma-t-butyl-L:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148c9d8b8bc29942c5bdd1fcfcfa8a83
https://doi.org/10.1007/s10571-009-9402-6

Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity

Autor: Tsutomu Araki, Naoto Kadoguchi, Hitoshi Maegawa, Toshiki Himeda, Yuko Kamiyama, Hiroyuki Kato

Publikováno v: Neuropharmacology. 50:329-344

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes the damage of dopaminergic neurons as seen in Parkinson's disease. Oxidative stress has been as one of several pathogenic hypotheses for Parkinson's disease. Here we investigated whether arun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57be1dc213983439366e337d6fb57e6
https://doi.org/10.1016/j.neuropharm.2005.09.014

List of Contributors

Autor: Bernhard Aigner, Akira Andoh, Lina Badimon, Alexandre Benani, Ross A. Breckenridge, Daniel Butzke, Andrew V. Caprariello, Laura Casani, Lucas M. Chaible, Li Chen, Mengqi Chen, K. Yeon Choi, Mohammed Emamussalehin Choudhury, Iain J. Clarke, Kristine Coleman, John L. Daiss, Frédérique Datiche, Catherine M. Davis, Geoffrey A. Donnan, David Feifel, Peter Fickert, Marcus A. Finzi Corat, Xavier Fioramonti, Christopher H. Fry, Sharyl Fyffe-Maricich, Ann-Christin Gaupel, Steven R. Goldberg, Yoichi Gondo, Barbara Grune, Belinda A. Henry, David W. Howells, Joshua G. Hunter, Soudabeh Imanikia, Rita I. Jabr, Naoto Kadoguchi, Lixin Kan, Jiro Kasahara, Stephen L. Kates, Matthew W. Kemp, Barbara Kessler, Saeed R. Khan, Denise Kinoshita, Nikolai Klymiuk, Ryuta Koyama, Doris Kretzschmar, Josephine Kugler, Jitka Kuncova, Maki Kuro, Mayuko Kurome, Michael Lardelli, Heather A. Lawson, Edmund Chun Yu Lee, Corinne Leloup, Lars Lewejohann, Manfred Liebsch, Fabienne Lienard, James Lokensgard, Andreas Luch, Malcolm R. Macleod, Meghan E. McGee-Lawrence, Alistair McGregor, Robert H. Miller, Atsushi Mizoguchi, Sarah Mordan-McCombs, Gabrielle C. Musk, Aysegul Nalca, Masahiro Nomoto, Victoria E. O’Collins, Michael Oelgeschläger, Christoph H. Österreicher, Luc Penicaud, Marion J. Pollheimer, Simone Renner, Sara I. Ruiz, Masatoshi Saito, Scott Schachtele, Steven J. Schapiro, Charles W. Schindler, Edward M. Schwarz, Frank J. Secreto, Andrea Seiler, Angela L. Shamchuk, Richard P. Shannon, You-Tang Shen, Paul D. Shilling, Dana Sittner, Gideon P. Smith, Milan Stengl, Stephen R. Stürzenbaum, Jitka Sviglerova, Farhan A. Syed, Jerrold Tannenbaum, Martin Tenniswood, Louise Thibault, Keith B. Tierney, Michael Trauner, Airo Tsubura, Judith Axler Turner, Giuseppe Verdile, Gemma Vilahur, Wei-Lin Winnie Wang, James L. Weed, JoEllen Welsh, Steffi Werler, Joachim Wistuba, Eckhard Wolf, Annegret Wünsch, Toshiyuki Yamamoto, Hironori Yokoyama, Katsuhiko Yoshizawa, Maria L. Zaidan Dagli, Caroline J. Zeiss, Elizabeth E. Zumbrun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16f8e600be6cf2585fa623d35f190cc0
https://doi.org/10.1016/b978-0-12-415894-8.01002-2

Failure of acute administration with proteasome inhibitor to provide a model of Parkinson's disease in mice

Autor: Hiroki Kimoto, Naoto Kadoguchi, Hiroyuki Kato, Ryohei Yano, Tsutomu Araki

Publikováno v: Metabolic brain disease. 23(2)

We investigated to determine whether acute administration of proteasome inhibitor can cause dopaminergic cell loss in mice, in comparison with that of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The four intraperitoneally administrations of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b2e4d507ee5fcaeab225dd47074dce
https://pubmed.ncbi.nlm.nih.gov/18425568