Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Naoto, Kosuga"'
1
Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as Factor Xa Inhibitors VI. A Series of New Derivatives Containing N,S- and N,SO2-Spiro Acetal Scaffolds
Autor: Fumihiko Saitoh, Hidemitsu Nishida, Yoshitaka Hosaka, Munetaka Ohkouchi, Naoto Kosuga, Ikuya Shiromizu, Tomokazu Matsusue, Ichiro Yamamoto, Miwa Matsumoto, Takafumi Mukaihira
Publikováno v: Chemical and Pharmaceutical Bulletin. 55:317-323
In the course of development of factor Xa (FXa) inhibitors, we have found unique compounds containing an N,O- and an N,N-spiro acetal structure. It appeared that the difference in overall conformation due to the N,X-spiro acetal structure might be im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b781fed7c810a4e565ae830ee7f451b
https://doi.org/10.1248/cpb.55.317
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3
Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors(1-6) VI. A series of new derivatives containing N,S- and N,SO2-spiro acetal scaffolds
Autor: Fumihiko, Saitoh, Hidemitsu, Nishida, Takafumi, Mukaihira, Naoto, Kosuga, Munetaka, Ohkouchi, Tomokazu, Matsusue, Ikuya, Shiromizu, Yoshitaka, Hosaka, Miwa, Matsumoto, Ichiro, Yamamoto
Publikováno v: Chemicalpharmaceutical bulletin. 55(2)
In the course of development of factor Xa (FXa) inhibitors, we have found unique compounds containing an N,O- and an N,N-spiro acetal structure. It appeared that the difference in overall conformation due to the N,X-spiro acetal structure might be im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2bf426d895bdd7e6b9cd5379bc8fec8
https://pubmed.ncbi.nlm.nih.gov/17268108
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