Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Naoto, Ito"'
Autor:
Nijiho Kawaguchi, Yukari Itakura, Kittiya Intaruck, Takuma Ariizumi, Michiko Harada, Satoshi Inoue, Ken Maeda, Naoto Ito, William W. Hall, Hirofumi Sawa, Yasuko Orba, Michihito Sasaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Rabies virus (RABV) is the causative agent of rabies, a lethal neurological disease in mammals. RABV strains can be classified into fixed strains (laboratory strains) and street strains (field/clinical strains), which have different properti
Externí odkaz:
https://doaj.org/article/e25253fd096c4d6f9921a52a36893677
Autor:
Miki Ando, Kazuki Nagata, Ryuki Takeshita, Naoto Ito, Sakura Noguchi, Natsuki Minamikawa, Naoki Kodama, Asuka Yamamoto, Takuya Yashiro, Masakazu Hachisu, Gaku Ichihara, Shigenobu Kishino, Masayuki Yamamoto, Jun Ogawa, Chiharu Nishiyama
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Various gut bacteria, including Lactobacillus plantarum, possess several enzymes that produce hydroxy fatty acids (FAs), oxo FAs, conjugated FAs, and partially saturated FAs from polyunsaturated FAs as secondary metabolites. Among these derivatives,
Externí odkaz:
https://doaj.org/article/0e40a4ee1a6a4500ab7dfe998f90a64d
Autor:
Naoki Kodama, Hikaru Okada, Masakazu Hachisu, Miki Ando, Naoto Ito, Kazuki Nagata, Mayuka Katagiri, Yayoi Yasuda, Ikumi Hiroki, Takuya Yashiro, Gaku Ichihara, Masayuki Yamamoto, Chiharu Nishiyama
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
Dendritic cells (DCs), which are typical antigen-presenting cells, localize to various sites in the body, particularly the front line of infection as sentinels, and are involved in innate and adaptive immune responses. Although the functions of DCs,
Externí odkaz:
https://doaj.org/article/ef4cb22f53c24cdaba6c6dc6a6180120
Autor:
Juri Matsuoka, Rina Minohara, Yuko Furuya, Kota Fukai, Haruna Hirosato, Naoto Ito, Kiminori Odagami, Tomohisa Nagata, Masako Nagata, Yuichi Kobayashi, Koji Mori
Publikováno v:
Environmental and Occupational Health Practice, Vol 3, Iss 1, Pp 1-7 (2021)
Objectives: To identify what types of information were useful and/or difficult to obtain for occupational physicians during the COVID-19 epidemic, and how information should be provided to help occupational physicians in the event of future outbreaks
Externí odkaz:
https://doaj.org/article/4963e811e8224761b25fe7cdbdd73b34
Autor:
Kazuki Nagata, Sanae Araumi, Daisuke Ando, Naoto Ito, Miki Ando, Yuki Ikeda, Miki Takahashi, Sakura Noguchi, Yayoi Yasuda, Nobuhiro Nakano, Tomoaki Ando, Mutsuko Hara, Takuya Yashiro, Masakazu Hachisu, Chiharu Nishiyama
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5997 (2023)
In the present study, we evaluated the effects of kaempferol on bone marrow-derived mast cells (BMMCs). Kaempferol treatment significantly and dose-dependently inhibited IgE-induced degranulation, and cytokine production of BMMCs under the condition
Externí odkaz:
https://doaj.org/article/b00c78312a2946548d5d8a506bcdac70
Autor:
Gayathri Manokaran, Michelle D Audsley, Haruka Funakoda, Cassandra T David, Katherine A Garnham, Stephen M Rawlinson, Celine Deffrasnes, Naoto Ito, Gregory W Moseley
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010533 (2022)
Antagonism of the interferon (IFN)-mediated antiviral state is critical to infection by rabies virus (RABV) and other viruses, and involves interference in the IFN induction and signaling pathways in infected cells, as well as deactivation of the ant
Externí odkaz:
https://doaj.org/article/38bb142f9a684fadbe3d07c7a9074010
Autor:
Yukari Itakura, Koshiro Tabata, Kohei Morimoto, Naoto Ito, Herman M. Chambaro, Ryota Eguchi, Ken-ichi Otsuguro, William W. Hall, Yasuko Orba, Hirofumi Sawa, Michihito Sasaki
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104122- (2022)
Summary: The amino acid residue at position 333 of the rabies virus (RABV) glycoprotein (G333) is a major determinant of RABV pathogenicity. Virulent RABV strains possess Arg333, whereas the attenuated strain HEP-Flury (HEP) possesses Glu333. To inve
Externí odkaz:
https://doaj.org/article/def4431757f545d38d1ca7d5829afe70
Autor:
Jingyu Zhan, Angela R Harrison, Stephanie Portelli, Thanh Binh Nguyen, Isshu Kojima, Siqiong Zheng, Fei Yan, Tatsunori Masatani, Stephen M Rawlinson, Ashish Sethi, Naoto Ito, David B Ascher, Gregory W Moseley, Paul R Gooley
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009729 (2021)
Rabies virus phosphoprotein (P protein) is a multifunctional protein that plays key roles in replication as the polymerase cofactor that binds to the complex of viral genomic RNA and the nucleoprotein (N protein), and in evading the innate immune res
Externí odkaz:
https://doaj.org/article/04e7c1bd948047038f0c27a6d86a6c67
Salicylaldehyde Suppresses IgE-Mediated Activation of Mast Cells and Ameliorates Anaphylaxis in Mice
Autor:
Tsubasa Ashikari, Masakazu Hachisu, Kazuki Nagata, Daisuke Ando, Yuki Iizuka, Naoto Ito, Kandai Ito, Yuki Ikeda, Hiroki Matsubara, Takuya Yashiro, Kazumi Kasakura, Chiharu Nishiyama
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8826 (2022)
Mast cells (MCs) play key roles in IgE-mediated immunoresponses, including in the protection against parasitic infections and the onset and/or symptoms of allergic diseases. IgE-mediated activation induces MCs to release mediators, including histamin
Externí odkaz:
https://doaj.org/article/b992f4881cd14db38914bf66d89a713a
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008767 (2020)
Many viruses target signal transducer and activator of transcription (STAT) 1 to antagonise antiviral interferon signalling, but targeting of STAT3, a pleiotropic molecule that mediates signalling by diverse cytokines, is poorly understood. Here, usi
Externí odkaz:
https://doaj.org/article/21d39d5fe9ea4f01af54e6bdda42ec57