Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Naotaka Nakazawa"'
Autor:
Yukari Fujimoto, Naotaka Nakazawa
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The cell has multiple mechanisms for sensing and responding to dynamic changes in the mechanical environment. In the process, intracellular signaling is activated to modulate gene expression. Recent studies have shown that multifunctional signaling m
Externí odkaz:
https://doaj.org/article/ec1b7373d5f64b45863c1458d6e982e2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/1fd29d48e09e4a35b5056159847fc117
Autor:
Naotaka Nakazawa, Mineko Kengaku
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neuronal migration is a critical step during the formation of functional neural circuits in the brain. Newborn neurons need to move across long distances from the germinal zone to their individual sites of function; during their migration, they must
Externí odkaz:
https://doaj.org/article/393d7d9127944d68ac115ac04cfc42f7
Autor:
Shimin Le, Xian Hu, Mingxi Yao, Hu Chen, Miao Yu, Xiaochun Xu, Naotaka Nakazawa, Felix M. Margadant, Michael P. Sheetz, Jie Yan
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2714-2723 (2017)
Summary: α-Actinins, a family of critical cytoskeletal actin-binding proteins that usually exist as anti-parallel dimers, play crucial roles in organizing the framework of the cytoskeleton through crosslinking the actin filaments, as well as in foca
Externí odkaz:
https://doaj.org/article/2bb50e12db49420da3892aa3fc69e6f2
Autor:
Mikiko Inaki, Ryo Hatori, Naotaka Nakazawa, Takashi Okumura, Tomoki Ishibashi, Junichi Kikuta, Masaru Ishii, Kenji Matsuno, Hisao Honda
Publikováno v:
eLife, Vol 7 (2018)
Polarized epithelial morphogenesis is an essential process in animal development. While this process is mostly attributed to directional cell intercalation, it can also be induced by other mechanisms. Using live-imaging analysis and a three-dimension
Externí odkaz:
https://doaj.org/article/2c2433d324fb4edca16a6de7529ca89c
Autor:
Yi-Ting Lai, Takeshi Sasamura, Junpei Kuroda, Reo Maeda, Mitsutoshi Nakamura, Ryo Hatori, Tomoki Ishibashi, Kiichiro Taniguchi, Masashi Ooike, Tomohiro Taguchi, Naotaka Nakazawa, Shunya Hozumi, Takashi Okumura, Toshiro Aigaki, Mikiko Inaki, Kenji Matsuno
Publikováno v:
Development. 150
Many internal Drosophila organs show stereotypical left-right (LR) asymmetry, for which the underlying mechanisms remain elusive. Here, we identified an evolutionarily conserved ubiquitin-binding protein, AWP1/Doctor no (Drn), as a novel factor requi
Autor:
Naotaka Nakazawa, Gianluca Grenci, Yoshitaka Kameo, Noriko Takeda, Tsuyoshi Sawada, Junko Kurisu, Zhejing Zhang, Taiji Adachi, Keiko Nonomura, Mineko Kengaku
Migration of newborn neurons is essential for brain morphogenesis and circuit formation, yet controversy exists regarding how neurons generate the driving force against strong mechanical stresses in crowded neural tissues. We found that cerebellar gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3db44d548f94a4c5ab35ed6453db22
https://doi.org/10.1101/2023.01.17.524464
https://doi.org/10.1101/2023.01.17.524464
Autor:
Tanita Frey, Tomonari Murakami, Koichiro Maki, Takumi Kawaue, Ayaka Sugai, Naotaka Nakazawa, Taiji Adachi, Mineko Kengaku, Kenichi Ohki, Yukiko Gotoh, Yusuke Kishi
Neurons decline in their functionality over time, and age-related neuronal alterations are associated with phenotypes of neurodegenerative diseases. In non-neural tissues, an infolded nuclear shape has been proposed as a hallmark of aged cells and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6653ff836bcaf7dba50356539c1aa245
https://doi.org/10.1101/2022.08.22.504704
https://doi.org/10.1101/2022.08.22.504704
Autor:
Bo Yang, Naotaka Nakazawa, Haguy Wolfenson, Shuaimin Liu, Junqiang Hu, Vin Yee Chung, Michael P. Sheetz, Ruby Yun-Ju Huang
Publikováno v:
Nature Materials. 19:239-250
A common feature of cancer cells is the alteration of kinases and biochemical signalling pathways enabling transformed growth on soft matrices, whereas cytoskeletal protein alterations are thought to be a secondary issue. However, we report here that
Autor:
Nobuyuki Kakiuchi, Shinichi Kotani, Naotaka Nakazawa, Hiroshi I. Suzuki, Ryunosuke Saiki, Daisuke Morishita, Toyonori Sakata, Yasunori Kogure, Masashi Sanada, Katsuhiko Shirahige, Rurika Okuda, Masanori Kakuta, Kengo Takeuchi, Akifumi Takaori-Kondo, Luca Malcovati, Eiji Sugihara, Tatsuaki Tsuruyama, Manabu Nakayama, Haruhiko Koseki, Satoru Miyano, Akihiko Yokoyama, Kenichi Yoshida, Mineko Kengaku, Keisuke Kataoka, Tetsuichi Yoshizato, Ayana Kon, Seishi Ogawa, Yusuke Shiozawa, Mario Cazzola, Takaaki Sato, Akinori Yoda, Hideki Makishima, Yasuhito Nannya, Yotaro Ochi, Masahiro Nakagawa, Tomomi Nishimura
Publikováno v:
Cancer Discov
STAG2 encodes a cohesin component and is frequently mutated in myeloid neoplasms, showing highly significant comutation patterns with other drivers, including RUNX1. However, the molecular basis of cohesin-mutated leukemogenesis remains poorly unders