Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Naoshi Ishikawa"'
Autor:
Yoko Matsuda, Toshiyuki Ishiwata, Naotaka Izumiyama-Shimomura, Hideki Hamayasu, Mutsunori Fujiwara, Ken-Ichiro Tomita, Naoki Hiraishi, Ken-Ichi Nakamura, Naoshi Ishikawa, Junko Aida, Kaiyo Takubo, Tomio Arai
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117575 (2015)
A large body of evidence supports a key role for telomere dysfunction in carcinogenesis due to the induction of chromosomal instability. To study telomere shortening in precancerous pancreatic lesions, we measured telomere lengths using quantitative
Externí odkaz:
https://doaj.org/article/84ee9315b8e14c51bcdf888cf5aaffce
Autor:
Youichi Kawano, Naoshi Ishikawa, Junko Aida, Yukihiro Sanada, Naotaka Izumiyama-Shimomura, Ken-ichi Nakamura, Steven S S Poon, Koshi Matsumoto, Koichi Mizuta, Eiji Uchida, Takashi Tajiri, Hideo Kawarasaki, Kaiyo Takubo
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93749 (2014)
Along with the increasing need for living-donor liver transplantation (LDLT), the issue of organ shortage has become a serious problem. Therefore, the use of organs from elderly donors has been increasing. While the short-term results of LDLT have gr
Externí odkaz:
https://doaj.org/article/2fda46b8d3df4ba0bd19fd27e03951f8
Autor:
Junko Aida, Akira Yokoyama, Naotaka Shimomura, Ken-ichi Nakamura, Naoshi Ishikawa, Masanori Terai, Steven Poon, Masaaki Matsuura, Mutsunori Fujiwara, Motoji Sawabe, Tomio Arai, Kaiyo Takubo
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63860 (2013)
Chromoendoscopy with Lugol iodine staining provides important information on the development of squamous cell carcinoma (SCC). In particular, distinct iodine-unstained lesions (DIULs) larger than 10 mm show a high prevalence in high-grade intraepithe
Externí odkaz:
https://doaj.org/article/87f560469ec34380bfd6e7f4e10cc64f
Autor:
Yuto Yamazaki, Keisuke Nonaka, Yoko Matsuda, Ja Mun Chong, Kaiyo Takubo, Naoshi Ishikawa, Tomio Arai, Hironobu Sasano, Junko Aida, Toshiyuki Ishiwata, Shoichiro Takakuma, Mototsune Kakizaki
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:5642-5650
Context Adrenocortical zonation is associated with a markedly complex developmental process, and the pathogenesis and/or etiology of many disorders of adrenocortical zonal development have remained unknown. Cells from the three adrenocortical zones a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201ae163b4f443c6954c35b2fc2c8632
https://doi.org/10.1210/jc.2019-00592
https://doi.org/10.1210/jc.2019-00592
Autor:
Yoko Matsuda, Ken-ichiro Tomita, Tomio Arai, Kaiyo Takubo, Misaki Yamada, Toshio Kumasaka, Kenichi Nakamura, Naoshi Ishikawa, Mutsunori Fujiwara, Junko Aida, Naotaka Izumiyama-Shimomura, Toshiyuki Ishiwata, Junko Takahashi-Fujigasaki, Naoki Hiraishi
Publikováno v:
Geriatrics & Gerontology International. 18:1507-1512
Aim The telomere is a structure present at the ends of chromosomes, and is known to shorten with aging and successive rounds of cell division. However, very little is known about telomere attrition in post-mitotic cells, such as neurons. Methods Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448d3af95f35b2040f1dbb5d12d5e2d4
https://doi.org/10.1111/ggi.13500
https://doi.org/10.1111/ggi.13500
Autor:
Naoshi Ishikawa, Tomio Arai, Kaiyo Takubo, Norihiko Sasaki, Yoko Matsuda, Hisashi Yoshimura, Junko Aida, Toshiyuki Ishiwata, Shunji Ishiwata
Publikováno v:
Pathology & Oncology Research. 24:797-805
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high incidence of distant metastasis and recurrence. Cancer stem cells (CSCs), which are pluripotent, self-renewable, and capable of forming tumors, contribute to PDAC initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c407cd512b63e1826695fd20860fe8
https://doi.org/10.1007/s12253-018-0420-x
https://doi.org/10.1007/s12253-018-0420-x
Autor:
Kaiyo Takubo, Yoko Matsuda, Junko Aida, Toshiyuki Ishiwata, Kimimasa Takahashi, Hisashi Yoshimura, Masami Yamamoto, Norihiko Sasaki, Tomio Arai, Masaki Michishita, Naoshi Ishikawa
Publikováno v:
Laboratory Investigation. 98:814-824
H19 is an oncofetal RNA expressed in the developing embryo as well as in bladder, breast, gastric, pancreatic, hepatocellular, and prostate cancers. Recent studies have shown that H19 enhances cancer invasion and metastasis; however, its roles in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4972e7c63661e0608c6283571746f05
https://doi.org/10.1038/s41374-018-0048-1
https://doi.org/10.1038/s41374-018-0048-1
Autor:
Norihiko Sasaki, Yoko Matsuda, Junko Aida, Toshiyuki Ishiwata, Fumio Hasegawa, Hiroki Kawai, Naoshi Ishikawa, Masaki Michishita, Tomio Arai, Masashi Toyoda, Kaiyo Takubo
Publikováno v:
Cancer Science
The expression of ATP‐binding cassette subfamily G member 2 (ABCG2) is related to tumorigenic cancer stem cells (CSC) in several cancers. However, the effects of ABCG2 on CSC‐related malignant characteristics in pancreatic ductal adenocarcinoma (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e0e92daa692a4966bea63cf9526bb6
https://doi.org/10.1111/cas.13533
https://doi.org/10.1111/cas.13533
Autor:
Yuto Aoki, Junko Aida, Youichi Kawano, Ken-ichi Nakamura, Naotaka Izumiyama-Shimomura, Naoshi Ishikawa, Tomio Arai, Yoshiharu Nakamura, Nobuhiko Taniai, Eiji Uchida, Kaiyo Takubo, Toshiyuki Ishiwata
Publikováno v:
Journal of Gastroenterology. 53:291-301
Congenital biliary dilatation (CBD) is a congenital malformation involving both dilatation of the extrahepatic bile duct and pancreaticobiliary maljunction. Persistent reflux of pancreatic juice injures the biliary tract mucosa, resulting in chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357212c9c5cbc1e2dbbc7c01ea04433f
https://doi.org/10.1007/s00535-017-1411-5
https://doi.org/10.1007/s00535-017-1411-5
Autor:
Tomio Arai, Tadayuki Takata, Yoko Matsuda, Atsuko Seki, Yuta Nakano, Daita Kaneda, Junko Takahashi-Fujigasaki, Kaiyo Takubo, Naoshi Ishikawa, Tan Wang, Junko Aida, Toshiyuki Ishiwata, Mototsune Kakizaki, Shigeo Murayama, Keisuke Nonaka, Motoji Sawabe
Publikováno v:
Geriatrics & Gerontology International. 18:211-215
Aim We aimed to clarify the characteristics of malignancies in older adults focusing on distant metastasis in the whole body. Methods We retrospectively evaluated 7710 cases of autopsies (4011 men, 3699 women, median age of 80 years), and analyzed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::505e3511d11c7f52bd48f4e25acb0a1f
https://doi.org/10.1111/ggi.13165
https://doi.org/10.1111/ggi.13165