Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Naomie Turgeon"'
Publikováno v:
Cells, Vol 10, Iss 2, p 224 (2021)
We have previously reported that histone deacetylase epigenetic regulator Hdac1 and Hdac2 deletion in intestinal epithelial cells (IEC) disrupts mucosal tissue architecture and barrier, causing chronic inflammation. In this study, proteome and transc
Externí odkaz:
https://doaj.org/article/05b5ee53e4d645c6918b9e81845376e7
Autor:
Naomie Turgeon, Mylène Blais, Julie-Moore Gagné, Véronique Tardif, François Boudreau, Nathalie Perreault, Claude Asselin
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73785 (2013)
Acetylation and deacetylation of histones and other proteins depends on histone acetyltransferases and histone deacetylases (HDACs) activities, leading to either positive or negative gene expression. HDAC inhibitors have uncovered a role for HDACs in
Externí odkaz:
https://doaj.org/article/5b0c670079274fc8962398735d3a5b06
Autor:
Christine Jones, Dominique Lévesque, Cassandra Couture, François Boudreau, Naomie Turgeon, François-Michel Boisvert, Alexis Gonneaud, Claude Asselin
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Both HDAC1 and HDAC2 are class I deacetylases acting as erasers of lysine-acetyl marks on histones and non-histone proteins. Several histone deacetylase inhibitors, either endogenous to the cell, such as the ketogenic β-hydroxybutyrate metabolite, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b093159321f579ee29fdad302c7f52c
http://link.springer.com/article/10.1038/s41598-019-41842-6
http://link.springer.com/article/10.1038/s41598-019-41842-6
Publikováno v:
Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 224, p 224 (2021)
Volume 10
Issue 2
Cells, Vol 10, Iss 224, p 224 (2021)
We have previously reported that histone deacetylase epigenetic regulator Hdac1 and Hdac2 deletion in intestinal epithelial cells (IEC) disrupts mucosal tissue architecture and barrier, causing chronic inflammation. In this study, proteome and transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851b29de8706f12a1292c2114f00524a
BACKGROUND: Histone deacetylase Hdac1 and Hdac2 regulate gene expression and protein function by removing acetyl groups on lysines. Hdac1 and Hdac2 influence many biological processes, from chromatin organization and cell differentiation, to cell cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e5d1350e63ff5f1554d528bb369607
https://europepmc.org/articles/PMC6507552/
https://europepmc.org/articles/PMC6507552/
Autor:
C Couture, Alexis Gonneaud, François-Michel Boisvert, Claude Asselin, François Boudreau, Naomie Turgeon, Christine Jones
BACKGROUND: Histone deacetylases HDAC1 and HDAC2 are homologous enzymes removing acetyl groups from histones and non-histone proteins. This epigenetic mark regulates many biological processes including cell proliferation and differentiation. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2f8b2781f7ff5137a0e0cb81f0a240
https://europepmc.org/articles/PMC6508277/
https://europepmc.org/articles/PMC6508277/
Autor:
Naomie Turgeon, Christine Jones, François-Michel Boisvert, Alexis Gonneaud, François Boudreau, Claude Asselin
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 2:284-285
BACKGROUND: INTRODUCTION: Deacetylases HDAC1 and HDAC2 are epigenetic erasers of acetyl marks on histones and transcription factors, among others, and thus regulate gene expression, cell proliferation and differentiation. We have shown that, in contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b199027495a9df1380af9ab5bbae4d
https://doi.org/10.1093/jcag/gwz006.142
https://doi.org/10.1093/jcag/gwz006.142
Autor:
Nathalie Rivard, Claude Asselin, François Boudreau, Alexis Gonneaud, Naomie Turgeon, Nathalie Perreault
Publikováno v:
Journal of Cellular Physiology. 231:436-448
The intestinal epithelium responds to and transmits signals from the microbiota and the mucosal immune system to insure intestinal homeostasis. These interactions are in part conveyed by epigenetic modifications, which respond to environmental change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11edc3a0bb8c12ceb5063fc6ed8c0e90
https://doi.org/10.1002/jcp.25090
https://doi.org/10.1002/jcp.25090
Autor:
François Boudreau, Mylène Blais, Fernand-Pierre Gendron, Claude Asselin, Naomie Turgeon, Julie Moore Gagné
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 306:G594-G605
Histone deacetylases (Hdac) remove acetyl groups from proteins, influencing global and specific gene expression. Hdacs control inflammation, as shown by Hdac inhibitor-dependent protection from dextran sulfate sodium (DSS)-induced murine colitis. Alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1215182cce33d8c3d57850b007d871
https://doi.org/10.1152/ajpgi.00393.2013
https://doi.org/10.1152/ajpgi.00393.2013
Autor:
Claude Asselin, Christine Jones, Alexis Gonneaud, Naomie Turgeon, François Boudreau, François-Michel Boisvert, Dominique Lévesque
Publikováno v:
Scientific Reports
Organoids have the potential to bridge 3D cell culture to tissue physiology by providing a model resembling in vivo organs. Long-term growing organoids were first isolated from intestinal crypt cells and recreated the renewing intestinal epithelial n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6629adc953ec2cd03dd1092d4101069
https://doi.org/10.1038/srep38195
https://doi.org/10.1038/srep38195