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pro vyhledávání: '"Naomi W. Court"'
Autor:
Vinochani Pillay, Layal Allaf, Alexander L. Wilding, Jacqui F. Donoghue, Naomi W. Court, Steve A. Greenall, Andrew M. Scott, Terrance G. Johns
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 5, Pp 448-458 (2009)
A common mutation of the epidermal growth factor receptor (EGFR) in glioblastoma multiforme (GBM) is an extracellular truncation known as the de2-7 EGFR (or EGFRvIII). Hepatocyte growth factor (HGF) is the ligand for the receptor tyrosine kinase (RTK
Externí odkaz:
https://doaj.org/article/1086668e9fe3428ba71bc3f816ce02a5
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1744:68-75
Stress-activated protein kinase-3 (SAPK3) is unique amongst the mitogen-activated protein kinase (MAPK) family with its C-terminal 5 amino acids directing interaction with the PDZ domain-containing substrates alpha1-Syntrophin and SAP90/PSD95. Here,
Autor:
Marie A. Bogoyevitch, Naomi W. Court
Publikováno v:
Cellular Signalling. 16:1345-1354
Signal transduction pathways in eukaryotic cells integrate diverse extracellular signals, and regulate complex biological responses such as growth, differentiation and death. One group of proline-directed Ser/Thr protein kinases, the mitogen-activate
Publikováno v:
Cardiovascular Research. 57:333-346
Objectives: The signal transduction pathways mediating the progression to failure have been intensively studied in a variety of in vitro and in vivo animal models. Recently, acute activation of the Janus kinases (JAKs) and signal transducers and acti
Publikováno v:
Journal of Molecular and Cellular Cardiology. 34:413-426
Cardiac expression and subcellular localisation of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK-3). . Cardiac Expression and Subcellular Localization of the p38 Mitogen-activated Protein Kinase Member, Stre
Autor:
Karen A. Draper, Marie A. Bogoyevitch, Lindy Abas, Naomi W. Court, Dominic C.H. Ng, Amardeep S. Dhillon
Publikováno v:
Journal of Molecular and Cellular Cardiology. 32:1469-1480
Oxidative stress has been proposed as a mediator of cardiac injury during ischemia and reperfusion. We examined the signalling events initiated by short-term exposure of cardiac myocytes to oxidative stress elicited by hydrogen peroxide. A potent sti