Inhibition of p38 Mitogen-Activated Protein Kinase and Transforming Growth Factor-β1/Smad Signaling Pathways Modulates the Development of Fibrosis in Adriamycin-Induced Nephropathy

Autor: Sharon D. Ricardo, Rong Jiao Liang, James A. Deane, John F. Bertram, Naomi Vittoria Campanale, Jinhua Li

Publikováno v: The American Journal of Pathology. 169:1527-1540

Inflammation and fibrogenesis are the two determinants of the progression of renal fibrosis, the common pathway leading to end-stage renal disease. The p38 mitogen-activated protein kinase (MAPK) and transforming growth factor (TGF)-beta1/Smad signal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f58c7f4e53ddd1ab30bc7263004d7a6
https://doi.org/10.2353/ajpath.2006.060169

Renal Structural and Functional Repair in a Mouse Model of Reversal of Ureteral Obstruction

Autor: Melissa H. Little, John F. Bertram, Anita Louise Cochrane, David A. Hume, Michelle M Kett, Sharon D. Ricardo, Chrishan S. Samuel, Warwick P Anderson, Naomi Vittoria Campanale

Publikováno v: Journal of the American Society of Nephrology. 16:3623-3630

The end point of immune and nonimmune renal injury typically involves glomerular and tubulointerstitial fibrosis. Although numerous studies have focused on the events that lead to renal fibrosis, less is known about the mechanisms that promote cellul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe9976b6d5c951df9c875d83e62da72
https://doi.org/10.1681/asn.2004090771

Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis

Autor: Sharon D. Ricardo, Claire E Hirst, Mary A Tonta, Bi Song, Martin A Short, Benjamin Reubinoff, Harold A. Coleman, Naomi Vittoria Campanale, Daniella Herszfeld, Sally Caine, Helena C. Parkington, Aude Sylvain, Claude C.A. Bernard, Guizhi Sun

Publikováno v: Stem cell research. 8(2)

The recent introduction of technologies capable of reprogramming human somatic cells into induced pluripotent stem (iPS) cells offers a unique opportunity to study many aspects of neurodegenerative diseases in vitro that could ultimately lead to nove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd118038f3e5435ac00cc772febc7dca
https://pubmed.ncbi.nlm.nih.gov/22265745

Early detection of the chemical changes occurring during the induction and prevention of autoimmune-mediated demyelination detected by FT-IR imaging

Autor: Naomi Vittoria Campanale, Mark J. Tobin, Sally Caine, Claude C.A. Bernard, Bayden R. Wood, Donald McNaughton, Philip Heraud, Tara Karnezis

Publikováno v: NeuroImage. 49(2)

Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS). Despite progress in understanding immunogenetic aspects of this disease, the mechanisms involved in lesion formation are unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2045bfcc254bb8913b975df3b3fcc70f
https://pubmed.ncbi.nlm.nih.gov/19796690

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter

Autor: Tedjo Sasmono, Melissa H. Little, Kyra Woods, Darrin Taylor, Sharon D. Ricardo, David A. Hume, Sean M. Grimmond, Dmitry A. Ovchinnikov, Naomi Vittoria Campanale, Fiona K. Rae

Publikováno v: Rae, F, Woods, K, Sasmono, T, Campanale, N, Taylor, D, Ovchinnikov, D A, Grimmond, S M, Hume, D A, Ricardo, S D & Little, M H 2007, ' Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter ', Developmental Biology, vol. 308, no. 1, pp. 232-46 . https://doi.org/10.1016/j.ydbio.2007.05.027
Monash University

All solid organs contain resident monocyte-derived cells that appear early in organogenesis and persist throughout life. These cells are critical for normal development in some organs. Here we report the use of a previously described transgenic line,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bba5b8797aacfb71201464b888f677
https://pubmed.ncbi.nlm.nih.gov/17597598