Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Naomi Takei-Masuda"'
Autor:
Mari Maeda, Mohamed Mahdi Alshahni, Yuji Tabata, Kazunori Maebashi, Shigeru Abe, Sho Takahata, Kubota Natsuki, Tsuyoshi Yamada, Naomi Takei-Masuda
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:873-880
Despite the existing treatment options for onychomycosis, there remains a strong demand for potent topical medications. ME1111 is a novel antifungal agent that is active against dermatophytes, has an excellent ability to penetrate human nails, and is
Autor:
Sho Takahata, Naomi Takei-Masuda, Makoto Ohyama, Yuji Tabata, Maiko Iida, Kazunori Maebashi, Kubota Natsuki, Kaori Kaneda
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:1035-1039
Fungal nail infection (onychomycosis) is a prevalent disease in many areas of the world, with a high incidence approaching 23%. Available antifungals to treat the disease suffer from a number of disadvantages, necessitating the discovery of new effic
Autor:
Kaori Kaneda, Yuji Tabata, Naomi Takei-Masuda, Sho Takahata, Yu Nagira, Xiaoying Hui, Masahiro Nomoto, Natsuki Kubota-Ishida, Howard I. Maibach, Tsubasa Chikada, Kazunori Maebashi
Publikováno v:
Antimicrobial agents and chemotherapy, vol 62, iss 1
ME1111 is a novel antifungal agent currently under clinical development as a topical onychomycosis treatment. A major challenge in the application of topical onychomycotics is penetration and dissemination of antifungal agent into the infected nail p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9606d621f3ccbe3379f8bba134472b2
https://europepmc.org/articles/PMC5740379/
https://europepmc.org/articles/PMC5740379/
Autor:
Rie Shinei, Naomi Takei Masuda, Yuji Tabata, Kenichi Kurihara, Yasushi Kurata, Shigeru Hoshiko, Tsuneo Okonogi, Yumiko Iizuka
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 313:916-920
We have isolated PF1092A, B, and C, novel nonsteroidal progesterone ligands with preferential affinity for the progesterone receptor, from fermentation broth of a fungus [Tabata Y, Miike N, Hatsu M, Kurata Y, Yaguchi T, Someya A, Miyadoh S, Hoshiko S
Autor:
Yuji Tabata, Rie Shinei, Yasushi Kurata, Ken ichi Kurihara, Tsuneo Okonogi, Yumiko Iizuka, Naomi Takei Masuda, Shigeru Hoshiko
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 82:217-223
We studied the pharmacological effects of novel nonsteroidal progesterone receptor antagonists CP8661 and CP8754, which were synthesized from the fungal metabolite PF1092C. CP8661 possess a tetrahydrobenzindolone skeleton and CP8754 possess a tetrahy
Autor:
Yasushi Kurata, Kenichi Kurihara, Naomi Takei Masuda, Yuji Tabata, Tsuneo Okonogi, Shigeru Hoshiko, Rie Shinei, Yumiko Iizuka, Junko Kashiwa
Publikováno v:
European journal of pharmacology. 430(2-3)
The potential of new nonsteroidal progesterone receptor ligands, the derivatives of PF1092C ((4aR,5R,6R,7S)-6,7-dihydroxy-4a,5,6,7-tetrahydro-3,4a,5-trimethylnaphtho[2,3-b]furan-2(4H)-one) discovered from fungal metabolites, was evaluated. PF1092A ((