Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Naomi Nagaya"'
Publikováno v:
Psychoneuroendocrinology. 141:105776
The increased susceptibility of women to stress and trauma-related disorders compared to men suggests a role for ovarian hormones in modulating fear and anxiety. In both humans and rodents, estrogen and progesterone have been shown to influence fear
Gonadal steroids and their metabolites have been shown to be important modulators of emotional behavior. Allopregnanolone (ALLO), for example, is a metabolite of progesterone that has been linked to anxiety-related disorders such as posttraumatic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba464834ad44a5d9711e18242cdd769d
https://europepmc.org/articles/PMC5381271/
https://europepmc.org/articles/PMC5381271/
Autor:
Stephen Maren, Naomi Nagaya
Publikováno v:
Biological Psychiatry. 78:152-153
Psychiatric illness is not an “equal opportunity” disease. For example, the lifetime prevalence of posttraumatic stress disorder (PTSD) is twice as high in women than in men. In recent years, gonadal steroids have moved into the spotlight as a po
Autor:
Naomi Nagaya, Diane M. Papazian
Publikováno v:
Journal of Biological Chemistry. 272:3022-3027
We have characterized the maturation of Shaker K+ channel protein and the cellular site of assembly of pore-forming alpha and cytoplasmic beta subunits in a transfected mammalian cell line. Shaker protein is made as a partially glycosylated, immature
Autor:
Naomi Nagaya, Albert A. Herrera
Publikováno v:
The Journal of Physiology. 483:141-153
1. The effects of testosterone on synaptic efficacy were studied in the flexor carpi radialis, a sexually dimorphic forelimb muscle involved in frog clasping behaviour. Male Xenopus laevis frogs were castrated and then given either testosterone-fille
Publikováno v:
Journal of Neurocytology. 19:85-99
The fluorescent dye 4-(4-diethylaminostyryl)-N-methylpyridinium iodide was used as a vital stain to study remodelling of motor nerve terminals in sartorius muscles of living frogs (Rana pipiens). Identified terminals were observed twice in vivo at in
Publikováno v:
The Journal of biological chemistry. 280(28)
P2X receptors are ATP-gated ion channels made up of three similar or identical subunits. It is unknown whether ligand binding is intersubunit or intrasubunit, either for agonists or for allosteric modulators. Zinc binds to rat P2X2 receptors and acts
Publikováno v:
International archives of allergy and immunology. 139(1)
Background: In patients with bronchial asthma an effective treatment is required at early stages of the disease to prevent irreversible structural changes of the airways. The objective of this study was to evaluate the beneficial effects of our routi
Autor:
Robert L. Macdonald, Naomi Nagaya
Publikováno v:
The Journal of physiology. 532(Pt 1)
The sensitivity of GABAA receptors (GABARs) to Zn2+ inhibition depends on subunit composition. The predominant neuronal forms of mammalian GABARs, αβγ and αβδ, are differentially sensitive to Zn2+ inhibition; αβγ receptors are substantially
Publikováno v:
The Journal of biological chemistry. 273(40)
In the voltage-dependent Shaker K+ channel, distinct regions of the protein form the voltage sensor, contribute to the permeation pathway, and recognize compatible subunits for assembly. To investigate channel biogenesis, we disrupted the formation o