Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Naomi Murai"'
Publikováno v:
Allergology International, Vol 61, Iss 3, Pp 439-449 (2012)
Background: Although budesonide/formoterol (BUD/FORM) is used clinically as a steroid/2-agonist single inhaler, it has not yet been clarified whether BUD/FORM has inotropic effects on diaphragm muscles after inhalation. Methods: We examined the effec
Externí odkaz:
https://doaj.org/article/0ba4eeefd937430cbffb02ce3fddd6dc
Autor:
Masahito Miura, Chiyohiko Shindoh, Tetsuya Handoh, Yuhto Taguchi, Naomi Murai, Tsuyoshi Nagano, Bruno D. Stuyvers, Minami Satoh, Satoshi Miyata, Lawson Miller
Publikováno v:
Circulation Journal. 80:76-84
BACKGROUND Connexin43 (Cx43) is a major connexin that forms gap junction (GJ) channels in the heart and is also present in the cell membrane as unopposed/non-junctional hemichannels and in the inner mitochondrial membrane. By using carbenoxolone (CBX
Publikováno v:
Allergology International, Vol 61, Iss 3, Pp 439-449 (2012)
Background: Although budesonide/formoterol (BUD/FORM) is used clinically as a steroid/2-agonist single inhaler, it has not yet been clarified whether BUD/FORM has inotropic effects on diaphragm muscles after inhalation. Methods: We examined the effec
Autor:
Penelope A. Boyden, Taiki Hattori, Bruno D. Stuyvers, Masahito Miura, Chiyohiko Shindoh, Naomi Murai, Taichi Nishio
Publikováno v:
Circulation. 121:2711-2717
Background— Arrhythmias are benign or lethal, depending on their sustainability and frequency. To determine why lethal arrhythmias are prone to occur in diseased hearts, usually characterized by nonuniform muscle contraction, we investigated the ef
Autor:
Xiao-Ming Guan, Osamu Okamoto, Takahiro Fukuroda, Tomoyuki Ohe, Nagaaki Sato, Akira Gomori, Takehiro Fukami, Masaru Nishikibe, Yuko Mitobe, Hiroko Matsushita, Masaki Ihara, Lex M.T. Van Der Ploeg, Akio Kanatani, Naomi Murai, Hisashi Iwaasa, Masayasu Hidaka, Shin Ichiro Egashira, Takeshi Tanaka, Douglas J. MacNeil, Makoto Jitsuoka, Yasuyuki Ishii, Satoshi Mashiko, Akane Ishihara, Takashi Murai
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7154-7158
Neuropeptide Y (NPY) is thought to have a major role in the physiological control of energy homeostasis. Among five NPY receptors described, the NPY Y5 receptor (Y5R) is a prime candidate to mediate some of the effects of NPY on energy homeostasis, a
Autor:
Takahiro Fukuroda, Tomoyuki Ohe, Naomi Murai, Yuji Haga, Akane Ishihara, Yasuyuki Ishii, Tetsuya Kanno, Satoshi Mashiko, Osamu Okamoto, Akio Kanatani, Masaki Ihara, Mikiko Hata, Takehiro Fukami
Publikováno v:
Molecular Pharmacology. 59:501-505
Neuropeptide Y (NPY) is a potent feeding stimulant. The orexigenic effect of NPY might be caused in part by the action of Y1 receptors. However, the existence of multiple NPY receptors including a possible novel feeding receptor has made it difficult
Autor:
Van der Ploeg Lh, Junko Ito, Masaki Ihara, Satoshi Mashiko, Nishimura S, Takehiro Fukami, Sugimoto N, Naomi Murai, Akio Kanatani, Nancy R. Morin, Saga Y, Douglas J. MacNeil, Takahiro Fukuroda
Publikováno v:
Endocrinology. 141:1011-1016
Neuropeptide Y (NPY) increases food intake through the action of hypothalamic NPY receptors. At least six subtypes of NPY, peptide YY (PYY), and pancreatic polypeptide (PP) receptors have been identified in mice. Although the involvement of Y1 and Y5
Autor:
Masanobu Oshima, Yumiko Saga, Hisashi Ohta, Nami Nakai, Naomi Murai, Masahiko Kobayashi, Makoto Mark Taketo
Publikováno v:
Genes to Cells. 4:219-228
BACKGROUND Retinoid X receptors RXRalpha, beta and gamma exert multiple functions in the genetic regulation of mammalian signalling systems by forming heterodimeric complexes with several nuclear ligand receptors. In contrast to the widespread expres
Autor:
Taiki Hattori, Tsuyoshi Nagano, Chiyohiko Shindoh, Masahito Miura, Naomi Murai, Bruno D. Stuyvers
Publikováno v:
Journal of molecular and cellular cardiology. 56
Ca(2+) waves are initiated not only by Ca(2+) leak from the sarcoplasmic reticulum (SR), but also by Ca(2+) dissociation from the myofilaments in the myocardium with nonuniform contraction. We investigated whether contractile properties and the produ
Autor:
Taichi Nishio, Tsuyoshi Nagano, Taiki Hattori, Naomi Murai, Masahito Miura, Chiyohiko Shindoh, Penelope A. Boyden
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 302(11)
In the ischemic myocardium, extracellular potassium ([K+]o) increases to ≥20 mmol/l. To determine how lethal arrhythmias occur during ischemia, we investigated whether the increased spatial pattern of [K+]o, i.e., a regional or a global increase, a